21 replies to this topic

[rhodeder]

I was interested in what drugs are the most powerful to enhance self-awareness, cognitive power and memory.

[rhodeder]

I'll just go ahead and add some that i found through some searching:
Adderall, Ritalin, Dexadrine, Modafinil seem like all good cognitive enhancers that are commonly used among large universities like oxford and harvard by people without ADHD or Narcolepsy. The only thing i can think that is illegal based cognitive enhancers are methampetamines which are really similar to amphetamine salt based cognitive enhancing prescription medicine. All these drugs though have some nasty side effects when you stop taking them and should be taken with caution.

[russianBEAR]

Wait, are we talking about "temporary high" or actual "cognitive enhancement"?

There's no way any amphetamine is an enhancer because they all cause dopamine toxicity in the brain (meth especially) and leads to very bad heart problems. They're also not exactly a caress to the liver and kidneys...Great for your teeth also!

As far as the effects, it simply creates an illusion that you're thinkin more clear and are in control, while in reality most of your actions indicate that you are completely delusional. I'm not talkin low time-release dosages of Adderall here...

Sure it's easy to zone in on some study when you're so high you think it's the best thing ever...Wouldn't say it's an enhancer since it's long term effects are degrading...



I'd say Cerebrolysine and Cortexin are the strongest enhancers that I've tried, but they don't work in a conventional way, so you may be better off getting your brain acquainted with some basics like GABA and Piracetam first to understand the mechanism of action etc.

[NootropicEU]

Wait, are we talking about "temporary high" or actual "cognitive enhancement"?

There's no way any amphetamine is an enhancer because they all cause dopamine toxicity in the brain (meth especially) and leads to very bad heart problems. They're also not exactly a caress to the liver and kidneys...Great for your teeth also!

As far as the effects, it simply creates an illusion that you're thinkin more clear and are in control, while in reality most of your actions indicate that you are completely delusional. I'm not talkin low time-release dosages of Adderall here...

Sure it's easy to zone in on some study when you're so high you think it's the best thing ever...Wouldn't say it's an enhancer since it's long term effects are degrading...



I'd say Cerebrolysine and Cortexin are the strongest enhancers that I've tried, but they don't work in a conventional way, so you may be better off getting your brain acquainted with some basics like GABA and Piracetam first to understand the mechanism of action etc.

Is Cerebrolysat as effective as Cerebrolysin? It seems to be much cheaper...

[rhodeder]

Wait, are we talking about "temporary high" or actual "cognitive enhancement"?

There's no way any amphetamine is an enhancer because they all cause dopamine toxicity in the brain (meth especially) and leads to very bad heart problems. They're also not exactly a caress to the liver and kidneys...Great for your teeth also!

As far as the effects, it simply creates an illusion that you're thinkin more clear and are in control, while in reality most of your actions indicate that you are completely delusional. I'm not talkin low time-release dosages of Adderall here...

Sure it's easy to zone in on some study when you're so high you think it's the best thing ever...Wouldn't say it's an enhancer since it's long term effects are degrading...



I'd say Cerebrolysine and Cortexin are the strongest enhancers that I've tried, but they don't work in a conventional way, so you may be better off getting your brain acquainted with some basics like GABA and Piracetam first to understand the mechanism of action etc.

H

How did you manage to try out Cerebrolysine? Well i think the release of Dopamine is the whole point. Heres a excerpt from wikipedia: Psychological effects of dextroamphetamine can include euphoria (via increased dopamine and serotonin), anxiety (via increased norepinephrine), altered libido, increased alertness, increased concentration, increased energy, increased self-esteem, increased self-confidence, increased excitation, increased orgasmic intensity, increased sociability, increased irritability, increased aggression, psychomotor agitation, hubris, excessive feelings of power and/or superiority, repetitive and/or obsessive behaviors, paranoia and amphetamine psychosis can occur.

[bgwithadd]

I was interested in what drugs are the most powerful to enhance self-awareness,

What a laugh.

cognitive power and memory.

None really do much usefully in this respect. They can increase concentration (often too much) but unless you have poor concentration that is not helpful in any way. basically it makes you more OCd. When viewed in that light it's a really stupid thing to want its effects unless you have an extreme tendency in the other direction. of course if you just want to get euphoria then adderall is the best but you will eat through brain cells fast at the doses needed for that.

[outsider]

I was interested in what drugs are the most powerful to enhance self-awareness, cognitive power and memory.

Well today I snorted 100 mg nefiracetam and I was amazed at the level of "self-awareness", the term is really good here, of my surrounding, it's like I could see more with better concentration.

My best stack was with Pyritinol 800 mg and piracetam. Very good for understanding, I was surprised that it worked so well. Now I will combine them in future for a powerful basic stack (100 mg intranasal nefiracetam, 800 mg Pyritinol and piracetam, I believe it will give great results). I'm out of pyritinol.

I'm talking about intranasal for minimizing nefiracetam potential toxicity, I don't think 100 mg is any treat. I'm taking aphrodisiacs and antioxidants so my balls are being taken care of.

[meursault]

Well today I snorted 100 mg nefiracetam

Pretty dumb. Please don't do it again. You could do some pretty bad damage to your nasal passages...also consider that these drugs are not meant to be metabolized that way.

Edited by czukles, 05 July 2009 - 11:26 PM.

[rhodeder]

I read up on amphetamine based medication and illegal drugs I recommend you stay far away. Some amphetamine based medication can be helpful but can become addictive and produce lots of bad side effects.

[jackinbox]

I never tried it but 4-methylaminorex might be one those illegal substances you ask about. I don't think it's very common on the street market.

[outsider]

Pretty dumb. Please don't do it again. You could do some pretty bad damage to your nasal passages...also consider that these drugs are not meant to be metabolized that way.

Why ? Because you snorted cocaine and damaged your nose and your brain ? (joke, don't worry)

Snorting is a practice used in healing science like ayurveda in India. I don't believe that something that is absorbed through digestion could be damaging to your nose. There existe many ways to absorbs molecules in your body like DHEA or pregnenolone through the skin with a patch.

Vacha, which is an ayurvedic nootropic, can be snorted.

Edited by outsider, 08 July 2009 - 08:14 AM.

[russianBEAR]

Is Cerebrolysat as effective as Cerebrolysin? It seems to be much cheaper...

Mm...could have sworn I posted a reply to you earlier on this...I guess maybe not


Anyways cerebrolysat is a pain in the butt to inject (literally) unlike cerebrolysine which I'm convinced is laced with some kind of a painkiller. There's also a higher risk of gettin some mad cow encephalopathy from it since it's made out of a bull's brain basically  

It also didnt seem as powerful too me, there's a clear price to quality correlation here, cerebrolysine is about 10-15 times more expensive (dependin on ampule size) but it IS worth it all the way.

And since we're apparently now on the topic of illegal black market stimulants (hey I made up that black market part but I just like typing that) then the most cognitively-enhancing ones are IAP, PPP etc. The latter one is quite dangerous but the former apparently is great, I haven't tried either but erowid has some reports. Again I suggest DONT do drugs!

Edited by russianBEAR, 08 July 2009 - 12:35 PM.

[meursault]

Why ? Because you snorted cocaine and damaged your nose and your brain ? (joke, don't worry)

Snorting is a practice used in healing science like ayurveda in India. I don't believe that something that is absorbed through digestion could be damaging to your nose. There existe many ways to absorbs molecules in your body like DHEA or pregnenolone through the skin with a patch.

Vacha, which is an ayurvedic nootropic, can be snorted.

These are poor reasons to advocate intranasal ingestion of a drug that has no studies involving that kind of administration.

[outsider]

These are poor reasons to advocate intranasal ingestion of a drug that has no studies involving that kind of administration.

I know a couple of people who did it and had great results.

For exemple when you think about it everyone makes there own stack and it's never backed up by science completely because it would be impossible to do studies with all the possible combination but we do it anyway because it works and it is within common sense. And even more subtle everyone react differently to each substance; some people would feel completely miserable with medication X while 80% people respond well to that same treatment.

It doesn't go through the liver first, I'm aware about that.

I know what you mean, I know where you come from. It's just not my philosophy.

[russianBEAR]

Intranasal administration is quite pointless, even when it comes to cocaine. 

It is the preferred method, since it's been shown in movies and "promoted" the most really, but you can just as easily dip your pinkie in the bag and eat it up for the same, if not stronger effect. Noone does it though since they only see coke being snorted in popular culture.

When you snort, it gives you a shorter effect duration in some cases as well, plus you kind of do want to study whatever it is you're snorting and make sure there's no filler etc.  

Doing pure chemicals which are ok for that method is still better than cocoa leves extracted with kerosene, or whatever them Columbian drug lords use nowadays

[supernoober]

Does the liver first pass reduce the effectiveness of all drugs/supplements?

[outsider]

Intranasal administration is quite pointless, even when it comes to cocaine. 

It is the preferred method, since it's been shown in movies and "promoted" the most really, but you can just as easily dip your pinkie in the bag and eat it up for the same, if not stronger effect. Noone does it though since they only see coke being snorted in popular culture.

When you snort, it gives you a shorter effect duration in some cases as well, plus you kind of do want to study whatever it is you're snorting and make sure there's no filler etc.  

Doing pure chemicals which are ok for that method is still better than cocoa leves extracted with kerosene, or whatever them Columbian drug lords use nowadays

http://www.alandiash...s/tinnitus.html

"Treatment
Nasya
Vacha (Acorus calamus) oil nasya, has a powerful effect in calming and balancing the prana vayu. To obtain the maximum effect at the head (the seat of prana vayu), and to circumvent any side effects of hyperacidity or nausea which occasionally occur when vacha is ingested, vacha is used in this case as a nasal medication. A preparation of sesame oil medicated with calamus root is taken nasally, five drops per nostril, at night and in the morning. The nasya should be warmed to blood heat before administration."

And for Vacha, Gotu kola and Jatamansi

http://www.ayurveda....l_cleansing.pdf


The oldest science says that to obtain maximum effect in the head without the side effects is to use the intranasal way in some cases.

There is real evidence of intranasal administration.

Edited by outsider, 11 July 2009 - 08:05 AM.

[supernoober]

http://www.alandiash...s/tinnitus.html

"Treatment
Nasya
Vacha (Acorus calamus) oil nasya, has a powerful effect in calming and balancing the prana vayu. To obtain the maximum effect at the head (the seat of prana vayu), and to circumvent any side effects of hyperacidity or nausea which occasionally occur when vacha is ingested, vacha is used in this case as a nasal medication. A preparation of sesame oil medicated with calamus root is taken nasally, five drops per nostril, at night and in the morning. The nasya should be warmed to blood heat before administration."

And for Vacha, Gotu kola and Jatamansi

http://www.ayurveda....l_cleansing.pdf


The oldest science says that to obtain maximum effect in the head without the side effects is to use the intranasal way in some cases.

There is real evidence of intranasal administration.

Just wondering. What's wrong with swallowing it?

[outsider]

Just wondering. What's wrong with swallowing it?

Nothing. It's just that in some cases it is more appropriate to take it intranasally. 99% of the time it is best to take it the normal way. I was talking about taking nefiracetam intranasally to reduce the possible toxicity of this molecule. 100mg instead of 1g.

[russianBEAR]

http://www.alandiash...s/tinnitus.html

"Treatment
Nasya
Vacha (Acorus calamus) oil nasya, has a powerful effect in calming and balancing the prana vayu. To obtain the maximum effect at the head (the seat of prana vayu), and to circumvent any side effects of hyperacidity or nausea which occasionally occur when vacha is ingested, vacha is used in this case as a nasal medication. A preparation of sesame oil medicated with calamus root is taken nasally, five drops per nostril, at night and in the morning. The nasya should be warmed to blood heat before administration."

And for Vacha, Gotu kola and Jatamansi

http://www.ayurveda....l_cleansing.pdf


The oldest science says that to obtain maximum effect in the head without the side effects is to use the intranasal way in some cases.

There is real evidence of intranasal administration.

Sure, this is a nasal-specific preparation and it is oil-based. I was talking about snorting as a practice applied to powders, like most of the substances nowadays in hydrochloride or sulfate form. We're also talking about 5 drops per nostril versus snorting anything from 100mg to a gram or more depending on a substance.

Plus it's not really snorting is it, it's nose drops ? 

[X_Danny_X]

What a laugh.


None really do much usefully in this respect. They can increase concentration (often too much) but unless you have poor concentration that is not helpful in any way. basically it makes you more OCd. When viewed in that light it's a really stupid thing to want its effects unless you have an extreme tendency in the other direction. of course if you just want to get euphoria then adderall is the best but you will eat through brain cells fast at the doses needed for that.

so you are saying that these drugs and nootropics such Pyritinol, L-Huperzine A, Pramiracetam, etc. dont work if you have good concentration?

[SmartDrugs Mexico]

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