Highest Quality Piracetam?

Started by mercury , Mar 10 2004 01:57 AM

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#1 mercury

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Posted 10 March 2004 - 01:57 AM

I'm about to experiment with Piracetam for the first time, but I am leery of generic versions which are said to be less effective.

Perhaps we can list which brands we've taken and comment on their efficacy?

#2 LifeMirage

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Posted 10 March 2004 - 10:42 AM

Sherwyn's, UNI's, and Smart Nutrition are the current generic nootropil pills on the market.

Sherwyn's did not have a COA on file.
UNI's COA tested at 99.72%.
Smart Nutriton I'm awaiting their reply.

Below are the bulk Piracetam's.

Bulk Nutrition COA tested at 99.6%
Beyond-A-Century I'm waiting their reply.

#3 shpongled

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Posted 10 March 2004 - 06:50 PM

http://www.bulknutri...products_id=912

All the products we carry are tested for purity

#4 anjatalker

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Posted 11 March 2004 - 01:49 AM

Are you sure that Sherwyn's has a COA?

Even if it doesn't shouldn't the fact that there exists an actual Sherwyn's store (in Chicago, I think) lend their piracetam a bit more credibility that that of, say, Unique Nutrition, which only has an online presence?

#5 mercury

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Posted 11 March 2004 - 03:34 AM

Thanks for the info (and the info from those suppliers when you get it, LifeMirage).

#6 storm

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Location:Seattle, Wa.

Posted 11 March 2004 - 03:47 AM

http://www.bulknutri...products_id=912

All the products we carry are tested for purity

Also have great prices and service.... [lol]

#7 LifeMirage

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Posted 12 March 2004 - 03:15 AM

Even if it doesn't shouldn't the fact that there exists an actual Sherwyn's store (in Chicago, I think) lend their piracetam a bit more credibility that that of, say, Unique Nutrition, which only has an online presence?

Actually Sherwyn's Piracetam was being originally made by UNI first in 2003 until Sherwyn’s switch to a different supplier & stopped wholesaling their product to Nubrain, which in return Nubrain currently carries UNI’s Piracetam.

I obtained this information directly from all 3 sources.

Company/Contact person

Sherwyn’s/Edward.
Nubrain/George.
UNI/Steve.

#8 anjatalker

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Posted 12 March 2004 - 07:39 PM

Thanks for the info.

So do we know anything about Sherwyn's new supplier?

#9 chomsky

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Posted 12 March 2004 - 11:05 PM

Well, I would say the highest quality Piracetam is the UCB Pharmaceuticals brand, which have an "N" on each half of an orange 800 mg tablet. I have also used Sherywn's Piracetam, which didn't seem to have much qualitative difference with respect to subjective effects. I opened one of the caps up and tasted it, and it tasted just like the Piracetam powder Bulk Nutrition sells.

#10 anjatalker

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Posted 13 March 2004 - 08:57 PM

But don't most of those powders taste the same? (very bitter) According to someone else Sherwyn's stuff used to come from UNI and is now made by themselves, correct? Or are they actually using Bulk Nutrition's?

#11 axiombiological

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Posted 31 March 2004 - 06:13 AM

But don't most of those powders taste the same? (very bitter) According to someone else Sherwyn's stuff used to come from UNI and is now made by themselves, correct? Or are they actually using Bulk Nutrition's?

More than likely they are buying from a raw material supplier in California. I purchase my piracetam from them, as well as buy directly from Chinese suppliers. Aniracetam, oxiracetam, pyritinol, etc. are all easily sourced.

Hit me for prices.

#12

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Posted 31 March 2004 - 06:51 AM

Pramiracetam is what I think most people would use if it was more widely available, apparently it's the best analogue of Piracetam, the most potent.

#13 chomsky

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Posted 31 March 2004 - 06:12 PM

Pramiracetam is what I think most people would use if it was more widely available, apparently it's the best analogue of Piracetam, the most potent.

You're quite right about that, if only someone would carry it. I think it has been long enough for the demand to build, and whichever company gets it first will more likely than not see a large volume of sales requests.

#14

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Posted 01 April 2004 - 02:34 AM

Well while I want Pramiractam myself I think that a very high attack dose of Piracetam will give a similar effect. Besides Piracetam can be bought pretty cheap now.

#15 axiombiological

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Posted 04 April 2004 - 07:19 PM

Pramiracetam is what I think most people would use if it was more widely available, apparently it's the best analogue of Piracetam, the most potent.

There are newer racetams, such as nefiracetam, which has some nicotinic activity. Pramiracetam is very hard to source, I don't know if it is still being made.

#16

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Posted 04 April 2004 - 10:10 PM

What does nicotinic activity mean? Activity mimicing nicotine in the body? I did a quick search on nefiracetam and didn't find much other than a few studies and existential websites. So I guess nefiracetam is also unavailable, which leaves us in the same position as Pramiracetam at the moment.

Here's another interesting study on the cetams.

http://www.biopsychi...nefiracetam.htm

"Cellular mechanisms underlying the cognition-enhancing actions of piracetam-like nootropics were studied by recording Ca2+ channel currents from neuroblastoma x glioma hybrid (NG108-15) cells and Xenopus oocytes expressing Ca2+ channels. In NG108-15 cells, nefiracetam (1 microM) produced a twofold increase in L-type Ca2+ channel currents. A similar, but slightly less potent effect was observed with aniracetam, whereas piracetam and oxiracetam exerted no such effects. Cyclic AMP analogs mimicked the nefiracetam action. N-type Ca2+ channel currents inhibited by leucine (Leu)-enkephalin by means of inhibitory G proteins (Go/Gi) were recovered promptly by nefiracetam, whereas those inhibited by prostaglandin E1 via stimulatory G proteins were not affected by nefiracetam. Cells treated with pertussis toxin (500 ng/mL, > 20 hours) were insensitive to nefiracetam. In Xenopus oocytes functionally expressing N-type (alpha1B) Ca2+ channels and delta-opioid receptors, nefiracetam was also effective in facilitating the recovery from Leu-enkephalin-induced inhibition. These results suggest that nefiracetam, and possibly aniracetam, may activate N- and L-type Ca2+ channels in a differential way depending on how they recover from Go/Gi-mediated inhibition."

It's rather technical but from what I can make from it nefiracetam is the most potent of the an-, ox- and piracetams. The "twofold increase in L-type Ca2+ channel currents" from nefiracetam, and aniracetam's same result to a lesser extent demostrate this. The ox- and piracetams apparently have no effect in that area. So assuming an increase in L-type Ca2+ channel currents produces some sort of cognition enhancing effect then aniracetam is the most potent commercially available -racetam today. Of course my analysis could be flawed so that's why I have it sourced for others to decide.

#17 axiombiological

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Posted 05 April 2004 - 05:13 AM

What does nicotinic activity mean? Activity mimicing nicotine in the body? I did a quick search on nefiracetam and didn't find much other than a few studies and existential websites. So I guess nefiracetam is also unavailable, which leaves us in the same position as Pramiracetam at the moment.

It activates the same profile of cholinergic receptors, i.e. nicotinic vs. muscarinic, as nicotine. I don't think that nefiracetam is available for human use.

#18 pSimonKey

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Posted 05 April 2004 - 09:33 AM

http://www.mezziah.c...racetam_raw.htm

#19 chomsky

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Posted 09 April 2004 - 07:30 PM

I just got a bottle of Aniracetam from Nubrain (who is supplied by UNI). Where can I get a copy of the CoA?

#20 chomsky

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Posted 10 April 2004 - 05:41 PM

Just took the Aniracetam I got and all I can say is wow, definetley felt noticable effects from the first 750 mg.

#21

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Posted 10 April 2004 - 06:30 PM

How does it compare to Piracetam in your body? I know you're one to be skeptical about testimonials but hopefully that nature in you will make you a more objective self-experimenter in this case.

#22 chomsky

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Posted 11 April 2004 - 04:56 AM

Aniracetam, for me, seems to increase the fluidity of thought processes and stimulate overall mental capacity for abstraction (good to take for understanding philosophy). Whereas Piracetam would mostly tend to transiently increase creativity (which is a hard thing to measure), and at times increased attention span very mildly. To tell you the truth, most of the time of taking Piracetam, I had to really scrutinize as to whether or not my cognitive abilities had actually improved. Aniracetam seems to give a more noticable effect than any other smart drug I've tried... too bad it's so damn expensive, but you get what you pay for I guess.

#23

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Posted 11 April 2004 - 05:29 AM

Well if you'd be willing to show your support in getting Aniracetam bulk powder:

Http://forums.1fast400.com/? Showtopic=1183

If we get enough support, and if they can get a cheaper supplier, then Aniracetam might be attainable for the rest of us.

Otherwise if you want to go through the bulk chinese suppliers Aniracetam remains quite expensive. From what I've seen they sell in 1kg and 25kg amounts.

#24 chomsky

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Posted 11 April 2004 - 07:50 AM

I've also noticed that Chinese chemical suppliers are starting to manufacture and sell Pramiracetam. Won't be long until smart drug companies start selling it again.

I read on rec.smart.drugs that UNI will sell Aniracetam powder for cheaper than the capsules if you just contact them about it.

#25

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Posted 11 April 2004 - 05:15 PM

I just got a quote for Aniracetam from an asian supplier, needless to say I would bankrupt myself buying bulk from them. I'm really pulling for Bulk Nutrition to carry bulk Aniracetam.

I also emailed UNI a few minutes ago with hopes that they would sell me powder Aniracetam at a more reasonable price.

#26 D Sade

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Posted 16 April 2004 - 01:46 AM

Pramiracetam is still available in China. I'm working on an arrangement right now.

#27 rizzer

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Posted 22 April 2004 - 01:15 AM

I've got aniracetam (99.75%)

I'll sell it to any of the people in this thread for $100 for 240 grams including shipping to the U.S. ($115 for other countries)
$55 shipped for 120 grams.

I'm currently getting oxiracetam; should be here in 7-10 days; and pramiracetam I've been trying hard to get; but haven't been able to get samples supplied yet. One supplier claims he can get it though; but still haven't got a price back from him.

Mike
Smi2le.biz

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Highest Quality Piracetam?

#1 mercury

#2 LifeMirage

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#3 shpongled

#4 anjatalker

#5 mercury

#6 storm

#7 LifeMirage

#8 anjatalker

#9 chomsky

#10 anjatalker

#11 axiombiological

#12

#13 chomsky

#14

#15 axiombiological

#16

#17 axiombiological

#18 pSimonKey

#19 chomsky

#20 chomsky

#21

#22 chomsky

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