8 replies to this topic

[darla]

Hi,

What would be the best supplements out there for this condition? Particularly rotator cuff and achillies tendon.

thanks!

[kismet]

How old are you? Did you take a course of antibiotics in the last 12m? Did they happen to be quinolones?

I'd wager that physiotherapy might help and rot. cuff training ASAP.

Edited by kismet, 10 September 2009 - 10:41 PM.

[Centurion]

On the ball as always kismet.

Provided you haven't recently taken a quinolone, as kismet suggested (hope not!) I would recommend Cissus Quadrangularis, Vitamin C, White Tea and Bromelain

Physiotheraphy (if suitable, have those tendons ultrasounded first) would be a good idea

[Lufega]

Manganese will help your tendons and ligaments heal faster.

[Matt]

after having bilateral achilles tendinitis and tendinitis of both wrists from taking Ciprofloxacin, they took around 18 months to 'completely recover' (I think they have!). Consuming plenty of whey protein supplement, I took 3 x 25g servings a day (around 60g of whey), also good stretching is important.

[Lufega]

Manganese will help your tendons and ligaments heal faster.

Seems like Cipro interacts with some metals like manganese and magnesium. Could some of the side effects be caused because of lowered Mn in blood? Manganese is important for tendon and cartilage function and this could be a mechanism that leads to tears.

This study seems to imply that extra manganese, but not Iron, promotes tendon healing.

Regulation of the glycosylations of collagen hydroxylysine in chick embryo tendon and cartilage cells.

Anttinen H, Hulkko A.
The regulation of the glycosylations of hydroxylysine was studied in isolated chick-embryo cells by labelling with a [14C]lysine pulse. The course of the procollagen lysyl modifications was compared in tendon and cartilage cells, and the effect on the gycosylations of the degree of lysyl hydroxylation and the concentration of Mn2+ and Fe2+ were also studied, in tendon cells. Procollagen triple helix formation was inhibited in most experiments in order to eliminate the effect of this process on the continuation of the reactions. Both in the tendon and cartilage cells the intracellular lysyl modifications proceeded in a biphasic fashion. After an initial sharp linear increase, the reactions did not cease but were protracted at a slower but constant rate. Lysyl hydroxylation was followed by rapid galactosylation in both cell types and this was followed almost immediately by rapid glucosylation, suggesting a close association of the corresponding enzymes. The data further suggest that other factors must also exist, in addition to the differences in the timing of triple helix formation and the actual hydroxylysine content, which are responsible for the different amounts of galactose in the collagens synthesized by these cell types. The amount of glucosylgalactosylhydroxylysine nevertheless seemed to be determined by the available acceptor sites, i.e., the amount of galactosylhydroxylysine. In further experiments with tendon cells the oxygen participating in lysyl hydroxylation was displaced by nitrogen at various points in time. When the degree of lysyl hydroxylation was reduced to less than one-third of the original, the total amounts of glycosylated residues decreased correspondingly, but their proportion relative to total hydroxylysine remained unchanged. Extra Mn2+ increased the proportion of galactosylated hydroxylysine, suggesting that the activity of hydrosylysyl galactosyltransferase is not saturating in respect of the catalyzed reaction. Experiments on the addition of Fe2+ or its chelation by alpha, alpha'-dipyridyl gave indications that the presence of this co-factor is not required for either glycosylation reaction in isolated tendon cells.
PMID: 7417530 [PubMed - indexed for MEDLINE]

Stress deprivation enhances manganese superoxide dismutase expression in the rat patellar tendon.

Kitamura N, Tohyama H, Nishihira J, Hatano M, Suzuki M, Yasuda K.
Department of Sports Medicine and Joint Reconstruction Surgery, Hokkaido University School of Medicine, Kita-ku, Kita-15 Nishi 7, Sapporo 060-8638, Japan.
Manganese superoxide dismutase (Mn-SOD) is a key antioxidant enzyme that prevents reactive oxygen species (ROS) damage to biological tissues. Although Mn-SOD has been investigated for a variety of cells, little is known about its expression in the tendon, particularly in the stress-deprived condition. The present study demonstrated that Mn-SOD is excessively expressed in the cultured fibroblasts derived from the stress-deprived patellar tendon in the rat using subtractive hybridization analysis. In addition, we confirmed that the expression of Mn-SOD is up-regulated in the stress-deprived patellar tendon in vivo at both the mRNA and protein levels. These results suggest that Mn-SOD may play a role in regulating ROS and matrix degradation involving mechanical deterioration of the stress-deprived tendon tissue.

Edited by Lufega, 13 September 2009 - 02:19 PM.

[yucca06]

1) Ice. A pouch on your tendons for hours ed.

2) Aromatherapy : Eucalyptus citriodora (don't know the english name, sorry) : 2-3 drops 4-5 x/day

3) taurine (helps remove toxics from your tendons/muscles), up to 10-15g/d.

4) lots of water

Worked very well for me 10 days ago for my achillies tendon.

[tintinet]

...3) taurine (helps remove toxics from your tendons/muscles), up to 10-15g/d....

Any references to support this assertion?

[alexd]

I have had Achilles tendon problems in my right foot. A Doctor had me doing specific stretches which if you are not doing them then you should. They work. Steroid cream Vitorin helped but made the skin sensitive. One thing that surprisingly worked was a few drops of a marijuana based oil that is rubbed on topicly I was skeptical but felt there was minimal risk. This stuff worked very well. Analgesic affects and a reduction in swelling. Not common and illeagal in many states and circumstances.

Ok here is something interesting. I was looking at Wired.com on an article on shoes that allow something closer to running barefoot. Some people had claimed that barefoot running actually helped with tendon problems. There are a few types shoes there is one made by Vibram that has toes is blue and is simply ugly. Due to the fact that two of my toes on each foot are joined that could not be a choice for me unless one of us was customized. I bought a more conventional pair of Nike from Foot Locker on a sale and paid 58 bucks. These are called Nike "Free" line. The sole flexes in both directions and they go on like slippers, no tongue although they have laces and you pull up the back of the shoe with a bootstrap.

So far these shoes seemed to have helped a lot. One statement made was that running injuries since the advent of the original Nike type shares have not gone down. Nike has you break yourself in before you start running with the Free shoe because you use different muscles. This is a good thing. I am hoping to start running ones again. They are very comfortable. So far I have seen an improvement with just walking around. Watch out for fake Nike's on ebay. Got some from a woman who ended up refunding my money since they said 7.5 but were one half to one size smaller. She then told me how they had been too small for her husband. I think they were fakes . More conventional in design with a similar sole. A very different experience than the genuine article. Every once in a while Nike has sales on shoes, if you are lucky you can get a fair deal. Or try those Vibrams the wired article did mention that one of their negative aspects was that they are " ugly as vomit". I think they will work very well, but I can wear the Nike's without it being a big deal when not running.

Wired article http://www.wired.com...09/07/barefoot/

http://www.wired.com...fivefingers_kso

Edited by alexd, 16 September 2009 - 03:52 AM.