17 replies to this topic

[protoject]

Hey,
I've been taking this 'NOW' brand "Natural Reservatrol" for a couple of days. I get definite benefit from reservatrol BUT I'm curious if anyone here gets nausea/stomach upset at all. The other day when I took the reservatrol I vomited... and today I became really nauseas and felt like I was going to vomit, but luckily it has mostly passed by now (about half hour later).

I think it's important for me to mention that in this brand has the following in it:
Red Wine Extract
Polygonum Cupsidatum extract
green tea extract
grape seed extract

It also has a small amount of caffeine due to the green tea extract, but only 8 mg of caffeine per 2 pills, and I take 6 so it equals 24mg of caffeine, which is much less caffeine than I've had other days and those days it doesnt seem to bother me nearly that much.

just curious to know if anyone else has experienced this and if you have tried a different brand without having the same problem.

I know this happens sometimes with powerful extracts.. I used to take 5HT supplements over a year ago and it always made me get sick.. but I gathered that it might not have been the chemical itself bothering me but the strong root extract bothering my stomach..

P.s. my apologies if this has already been covered, I was having issues with the search function when typing in 'reservatrol' and 'nausea'. I also understand that my symptoms are a reaction that some other people experience but I just wanted to know if maybe it had to do with the form of the supplement.

Edited by protoject, 12 September 2009 - 02:53 PM.

[niner]

I dont think that I've ever heard nausea mentioned, but I'm not surprised considering everything that's in those pills, and the fact that you're taking six of them. I would recommend getting some 98+ % resveratrol. You will probably not have a problem with that. Green Tea and Grapeseed extracts are also worth taking, and might be partially responsible for the "feeling good" part of the experience. The components of the polygonum extract that are not resveratrol may also feel good. Resveratrol itself is not something that most healthy people "feel" in the short term. If you have inflammation, it might make that feel better. If you are borderline hypoglycemic, it might make you feel bad. If you don't have any conditions that resveratrol affects in the short term, then you might notice athletic improvements (primarily endurance) in the longer term. There should be no need for nausea, though.

[2tender]

I would stop taking anything that gave me nausea immediately. People think that just because something is marketed as being healthy, its good for them, thats the wrong assumption. Its possible you have an allergy to something in it, regurgitation is a symptom that something you have ingested is not good for you. Just my opinion and I hope that helps you.

[unglued]

I'd be interested in hearing what "definite benefits" you're observing? They must be pretty good, if you're considering trying different brands or doses until the minor side effect of vomiting goes away! I've been taking it for a couple of years and I've seen some not-so-definite long-term signs that my endurance has increased, but I look at that not as an end in itself but as a hopeful sign that it's making me healthier, i.e. keeping me younger. Or maybe that's what you meant -- that you're definitely convinced by what you've heard about the preliminary research that there will be benefits?

I second what's been said above: The most likely culprit is the 200 mg of miscellaneous stuff from the other 50% of the Polygonum cupsidatum, or less likely, the some component of the grape or green tea, not the 200 mg of resveratrol. Out of the hundreds of compounds in those herbs, if you're getting a bad reaction to one of them, chances are it's not the resveratrol. If you're motivated to try resveratrol and are having a bad reaction to this combination, it seems worth trying 200 mg of a 98% pure formulation instead.

[protoject]

I'd be interested in hearing what "definite benefits" you're observing? They must be pretty good, if you're considering trying different brands or doses until the minor side effect of vomiting goes away! I've been taking it for a couple of years and I've seen some not-so-definite long-term signs that my endurance has increased, but I look at that not as an end in itself but as a hopeful sign that it's making me healthier, i.e. keeping me younger. Or maybe that's what you meant -- that you're definitely convinced by what you've heard about the preliminary research that there will be benefits?

I second what's been said above: The most likely culprit is the 200 mg of miscellaneous stuff from the other 50% of the Polygonum cupsidatum, or less likely, the some component of the grape or green tea, not the 200 mg of resveratrol. Out of the hundreds of compounds in those herbs, if you're getting a bad reaction to one of them, chances are it's not the resveratrol. If you're motivated to try resveratrol and are having a bad reaction to this combination, it seems worth trying 200 mg of a 98% pure formulation instead.

The effects I get are pretty good. I experience more drive and energy and mood lift. It's hard to put my finger on the exact effect but I notice there's a definite effect there. Mind you, I haven't been experimenting with reservatrol for a long time. The way that I use supplements is that I use the ones that tend to have some sort of noticable effect that I'd like to explore, while learning about it and seeing if it's worth taking. I'm not a huge reservatrol enthusiast, but am still in the experimental and learning stages, that stage in which I've learnt that it makes me sick to my stomach for a period of time, and also tends to elevate my mood and I've felt physically healthier and with more energy. I agree that your assumption might be right; my supplement is only 50% reservatrol in the polygonum cupsidatum extract..

though I'm curious if there's anyone here who actually has experience with getting sick off something like my 'now'/generic brand supplement and having better success with a higher percentage of pure reservatrol without the 'leftovers' or 'additives'. Or just whatever reservatrol supplement they may have taken that differed in some way. That way I could avoid making another purchase for something that's going to make me ill again, or , be a bit more comfortable in making a better purchase if there is in fact a better purchase. Thank you for your responses.

EDIT: Oh! Forgot to mention some other effects which seem to be directly related to reservatrol since I've not been taking anything else. First of all, usually I urinate several times a day or feel urgency to urinate. I notice when i take reservatrol I go to the bathroom a lot less than usual/have less urgency to go to the bathroom. Also, my appetite has gone way down. Which for me is alright because I'm always hungry and I could eat all day and it becomes a huge distraction. [I'm not anywhere close to being a heavy person though]

Edited by protoject, 12 September 2009 - 11:29 PM.

[maxwatt]

I know a woman who says grape seed extracts make her nauseous. You took several times what is likelty the suggested dose on the bottle. There might be a connection.

[2tender]

Protoject, yes I have had bad experiences with certain brand name supplements, I moved on from those brands, its not unusual for that to happen people develop sensitivities to fillers, excipients, type of capsule etc. sometimes even the vitamin or formula itself, our physiology is in a state of flux and companies regularly change bulk suppliers of ingredients. I would suggest, of course, using a non-compounded pre-emulsified, 98% pure, micronized polygonum extract, with a verifiable COA from the leading manufacturer(s), you can find my comments and what has worked for me elsewhere throughout this board, Maxwatt, Anthony, and Niner and others, all have good posts regarding this subject. There is much wisdom here,read, think critically, and decide for yourself. I hope that helps you! There is more to supplementing long term than is evident and that is simply my opinion.

Edited by 2tender, 13 September 2009 - 02:25 AM.

[2tender]

I know a woman who says grape seed extracts make her nauseous. You took several times what is likelty the suggested dose on the bottle. There might be a connection.

Maxwatt, is your avatar a photo from an Ayahuasca ceremony? That person looks to be in a tryptamine trance.

[niner]

Maxwatt, is your avatar a photo from an Ayahuasca ceremony? That person looks to be in a tryptamine trance.

Or is it "the gimp"; the guy in the bondage getup from Pulp Fiction? Hard to say. Looks kinky, but that's probably just my mind at work...

[niner]

The effects I get are pretty good. I experience more drive and energy and mood lift. It's hard to put my finger on the exact effect but I notice there's a definite effect there. Mind you, I haven't been experimenting with reservatrol for a long time. The way that I use supplements is that I use the ones that tend to have some sort of noticable effect that I'd like to explore, while learning about it and seeing if it's worth taking. I'm not a huge reservatrol enthusiast, but am still in the experimental and learning stages, that stage in which I've learnt that it makes me sick to my stomach for a period of time, and also tends to elevate my mood and I've felt physically healthier and with more energy. I agree that your assumption might be right; my supplement is only 50% reservatrol in the polygonum cupsidatum extract..

though I'm curious if there's anyone here who actually has experience with getting sick off something like my 'now'/generic brand supplement and having better success with a higher percentage of pure reservatrol without the 'leftovers' or 'additives'. Or just whatever reservatrol supplement they may have taken that differed in some way. That way I could avoid making another purchase for something that's going to make me ill again, or , be a bit more comfortable in making a better purchase if there is in fact a better purchase. Thank you for your responses.

EDIT: Oh! Forgot to mention some other effects which seem to be directly related to reservatrol since I've not been taking anything else. First of all, usually I urinate several times a day or feel urgency to urinate. I notice when i take reservatrol I go to the bathroom a lot less than usual/have less urgency to go to the bathroom. Also, my appetite has gone way down. Which for me is alright because I'm always hungry and I could eat all day and it becomes a huge distraction. [I'm not anywhere close to being a heavy person though]

Protoject, your experiences are exactly what have been reported by a number of people taking largish (couple hundred mg) doses of 50% resveratol; mood elevation and appetite suppression. In addition, MANY people have noted GI symptoms. One of the components of "the other 50%" (these are not additives, they are non-removed compounds from the plant), Emodin, is an intestinal irritant that is known to cause diarrhea in many people. Along with the polygonum extract, there is green tea which can give a mood boost and might also be appetite suppressant. Unfortunately, it might be the case that the effect you like is due to something that causes you trouble. You may not be feeling the resveratrol at all. You could try green tea extract separately, and/or grapeseed extract. You could even experiment with a 50% resveratrol that doesn't have all the other extracts in it. I prefer to use pure forms of compounds so I know what is responsible for whatever effect I'm getting. I don't like these kitchen sink formulations.

[maxwatt]

I know a woman who says grape seed extracts make her nauseous. You took several times what is likelty the suggested dose on the bottle. There might be a connection.

Maxwatt, is your avatar a photo from an Ayahuasca ceremony? That person looks to be in a tryptamine trance.

It's a picture I took of a Northwest Native American mask in the collection of the Musueum of Anthropology at the University of British Columbia.
http://www.moa.ubc.ca/tour/index.html

Attached Files

•  mask.jpg   31.76KB   39 downloads

Edited by maxwatt, 13 September 2009 - 08:49 AM.

[2tender]

I knew it was aboriginal in some sense. The mind sees an actual human face in the smaller photo and not a mask, either thats surreal or I need to get that lasix. Thanks for posting the link and enlarged picture. Great avatar!

[Animal]

I knew it was aboriginal in some sense. The mind sees an actual human face in the smaller photo and not a mask, either thats surreal or I need to get that lasix. Thanks for posting the link and enlarged picture. Great avatar!

You can actually see through the eye holes to the background behind the mask, I don't know how you perceived a human face.

[niner]

I knew it was aboriginal in some sense. The mind sees an actual human face in the smaller photo and not a mask, either thats surreal or I need to get that lasix. Thanks for posting the link and enlarged picture. Great avatar!

You can actually see through the eye holes to the background behind the mask, I don't know how you perceived a human face.

Are you talking about the large picture? 2tender was talking about the avatar. If you can make out background in that, your ability to interpret low resolution pixels is better than mine.

[Animal]

I knew it was aboriginal in some sense. The mind sees an actual human face in the smaller photo and not a mask, either thats surreal or I need to get that lasix. Thanks for posting the link and enlarged picture. Great avatar!

You can actually see through the eye holes to the background behind the mask, I don't know how you perceived a human face.

Are you talking about the large picture? 2tender was talking about the avatar. If you can make out background in that, your ability to interpret low resolution pixels is better than mine.

The avatar was what I was referring to, I hadn't actually clicked on the larger picture until just now. Well I used to suffer from myopia until having laser surgery so my short vision is excellent.

[maxwatt]

I knew it was aboriginal in some sense. The mind sees an actual human face in the smaller photo and not a mask, either thats surreal or I need to get that lasix. Thanks for posting the link and enlarged picture. Great avatar!

You can actually see through the eye holes to the background behind the mask, I don't know how you perceived a human face.

Are you talking about the large picture? 2tender was talking about the avatar. If you can make out background in that, your ability to interpret low resolution pixels is better than mine.

The avatar was what I was referring to, I hadn't actually clicked on the larger picture until just now. Well I used to suffer from myopia until having laser surgery so my short vision is excellent.

It will deteriorate as your eyes age.

Without glasses I can see the individual pixels on my screen, and the avatar still reads as a face to me, unless I: a) get right on top of it, ) use Firefox's cntl++ function to enlarge it. Then the "eyes" can be seen clearly as the continuation of the window in the background.

Disclaimer: resveratrol has nothing to do with this.

[newshadow]

I'd be interested in hearing what "definite benefits" you're observing? They must be pretty good, if you're considering trying different brands or doses until the minor side effect of vomiting goes away! I've been taking it for a couple of years and I've seen some not-so-definite long-term signs that my endurance has increased, but I look at that not as an end in itself but as a hopeful sign that it's making me healthier, i.e. keeping me younger. Or maybe that's what you meant -- that you're definitely convinced by what you've heard about the preliminary research that there will be benefits?

I second what's been said above: The most likely culprit is the 200 mg of miscellaneous stuff from the other 50% of the Polygonum cupsidatum, or less likely, the some component of the grape or green tea, not the 200 mg of resveratrol. Out of the hundreds of compounds in those herbs, if you're getting a bad reaction to one of them, chances are it's not the resveratrol. If you're motivated to try resveratrol and are having a bad reaction to this combination, it seems worth trying 200 mg of a 98% pure formulation instead.

The effects I get are pretty good. I experience more drive and energy and mood lift. It's hard to put my finger on the exact effect but I notice there's a definite effect there. Mind you, I haven't been experimenting with reservatrol for a long time. The way that I use supplements is that I use the ones that tend to have some sort of noticable effect that I'd like to explore, while learning about it and seeing if it's worth taking. I'm not a huge reservatrol enthusiast, but am still in the experimental and learning stages, that stage in which I've learnt that it makes me sick to my stomach for a period of time, and also tends to elevate my mood and I've felt physically healthier and with more energy. I agree that your assumption might be right; my supplement is only 50% reservatrol in the polygonum cupsidatum extract..

though I'm curious if there's anyone here who actually has experience with getting sick off something like my 'now'/generic brand supplement and having better success with a higher percentage of pure reservatrol without the 'leftovers' or 'additives'. Or just whatever reservatrol supplement they may have taken that differed in some way. That way I could avoid making another purchase for something that's going to make me ill again, or , be a bit more comfortable in making a better purchase if there is in fact a better purchase. Thank you for your responses.

EDIT: Oh! Forgot to mention some other effects which seem to be directly related to reservatrol since I've not been taking anything else. First of all, usually I urinate several times a day or feel urgency to urinate. I notice when i take reservatrol I go to the bathroom a lot less than usual/have less urgency to go to the bathroom. Also, my appetite has gone way down. Which for me is alright because I'm always hungry and I could eat all day and it becomes a huge distraction. [I'm not anywhere close to being a heavy person though]

It sounds to me like you are borderline diabetic.If I am not wrong diabetics urinate frequently and insulin resistance makes hungrier.The resveratrol is modulating you insulin resistance and glucose levels.I would get a glucose tolerance test.

Cheers.

[protoject]

Just reporting back. I got another version of resveratrol from the same brand that's 400mg polygonum extract/ 50% reservatrol [200mg/pill], and 10% red wine extract. This gives me absolutely no problem with my stomach.