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Cadiolipin Antibodies found in Neuro and fatigue pathology


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#1 NG_F

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Posted 16 September 2009 - 02:24 PM


Here is an interesting sumary from Dr.Nicholson from MedHelp....

Anticardiolipin antibodies are found in most autoimmune disordersAdjustment disorder
Anorexia nervosa
Asperger syndrome
Autism
Autoimmune disorders
Bipolar disorder
Bipolar disorder
Bleeding disorders
Borderline personality disorder
Bulimia
Chronic motor tic disorder<script>hover_boxes.hoverize_link('term_4753253_1', 'highlight_term') and especially in those that involve decreased mitochondrial function (essentially all fatiguing illnesses and many other chronic illnesses, such as neurodegenerative diseases, neurobehavioral diseases, among other diseases). Cardiolipin is a specialized lipidCoronary risk profile
High blood cholesterol and triglycerides<script>hover_boxes.hoverize_link('term_4753253_2', 'highlight_term') that is mostly found in the inner mitochondrial membrane where it is essentialEssential hypertension
Essential tremor<script>hover_boxes.hoverize_link('term_4753253_3', 'highlight_term') for oxidative phosphorylation or the production of high-energy molecules in the cell that are necessary for metabolism and cell function. Reduction of the cardiolipin molecules results in leaky mitochondrial membranes, and these membranes must not be leaky or high-energy molecules can't be produced, resulting in fatigue. Infections damage cardiolipin and other membrane phospholipids by oxidation—the infectionsPosted Image produce peroxides that oxidize the membrane lipidsCoronary risk profile
High blood cholesterol and triglycerides<script>hover_boxes.hoverize_link('term_4753253_4', 'highlight_term'), and cardiolipin molecules are particularly sensitive. Once damaged, they must be removed and antibodies can be made against them during this process. These same oxidative events can damage the endothelial cells lining the blood vessels, resulting in increased platelet aggregation and increased production of platelets to compensate for this.




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