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Is Piracetam a long-time nootropic, or a short acting one like ampheta


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#1 dubrontsidah

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Posted 16 September 2009 - 10:11 PM


By nootropic I mean anything to increase ones mental capabilities.

My question is does Piracetam work over the long run by strengthening your brain, or does it act in the short time?

For example, amphetamine works WONDERS in the short run, but doesn't necessarily do anything over the long run.

I am already on prescription amphetamine and I don't think the 800mg of piracetam I have been taking 3 times a day with 6 eggs in the morning is doing anything.

Should I expect to wait a few weeks before I notice results?

Or should I just treat it like amphetamine, a short time cognitive enhancer, and multiply the dose until I find something that works for me?

#2 Healthy56

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Posted 17 September 2009 - 04:49 AM

By nootropic I mean anything to increase ones mental capabilities.

My question is does Piracetam work over the long run by strengthening your brain, or does it act in the short time?

For example, amphetamine works WONDERS in the short run, but doesn't necessarily do anything over the long run.

I am already on prescription amphetamine and I don't think the 800mg of piracetam I have been taking 3 times a day with 6 eggs in the morning is doing anything.

Should I expect to wait a few weeks before I notice results?

Or should I just treat it like amphetamine, a short time cognitive enhancer, and multiply the dose until I find something that works for me?



I'm not getting anything out of Piracetam either. I'm starting to feel like only SOME people get this supp to work.

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#3 csrpj

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Posted 17 September 2009 - 05:14 AM

piracetam has a very strong effect on me when i take it. i haven't experimented with taking it every day for a few weeks to see it it effects me when i'm not "on it" so i can't speak to that, but it is at least short-acting. i would very much like to know if it is also long-acting, as i've heard some people only start feeling affects after taking it everyday for a couple weeks.

#4 nito

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Posted 17 September 2009 - 05:21 AM

piracetam has a very strong effect on me when i take it. i haven't experimented with taking it every day for a few weeks to see it it effects me when i'm not "on it" so i can't speak to that, but it is at least short-acting. i would very much like to know if it is also long-acting, as i've heard some people only start feeling affects after taking it everyday for a couple weeks.


What are these strong effects that piracetam brings about?

#5 csrpj

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Posted 17 September 2009 - 06:35 AM

piracetam has a very strong effect on me when i take it. i haven't experimented with taking it every day for a few weeks to see it it effects me when i'm not "on it" so i can't speak to that, but it is at least short-acting. i would very much like to know if it is also long-acting, as i've heard some people only start feeling affects after taking it everyday for a couple weeks.


What are these strong effects that piracetam brings about?


it makes me really sharp. language, ideas, come super-quick. also, it sharpens my sense... leaves looks super crisp and trance sounds majestic. these are the two strongest affects, but i'm also happier, more social, and more focused on piracetam. also, combine it with weed, and for me the trip becomes something way stronger, similar to LSD in perceptual changes.

#6 Vultures

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Posted 17 September 2009 - 08:43 AM

Some thoughts from another noob.

I also find it hard to believe people, who report strong LSD- or speed-like effects from racetams, I guess effect can be strong only if you have some kind of defficiency. Placebo tend to work wonders as well=)
The trick with racetams and other "true" nootropics (as opposed to stimulants, like modafinil, or deprenyl) is that you'll hardly notice anything on subjective side, you won't get high, or particularly motivated, you won't get productivity boost, etc. If that's what you expect, stick on stimulants. However there are subtle effects that tend to build up over time, e.g. my nootropic stack helped to solve tong-tie problem (I used to stop occasionally for a few seconds, trying to remember some word). After a few weeks a number of "jigamies" in my speech was reduced significantly. Also, I am a translator, my general workflow is "reading source sentence - composing several options - picking the best - typing it", first 3 steps should happen real fast - fractions of a second. Nootropics seemed to help with this, subjectively the process became smoother, and faster.
Color perception changed as well, but not for better, and neither for worse... Just different.

Try to search "attack dosage" on this forum, this might be your solution.

PS: Phenotropil can be strong at the beginning, but that's a different story.

Edited by Vultures, 17 September 2009 - 10:20 AM.


#7 mdma

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Posted 17 September 2009 - 09:59 PM

I dont expect a single day out of it for the rest of my life. Thats how great i think Piracetam is. Its mainly long term for me, i dont feel it right away, i just know im more focused, more intelligent, more creative and i retain information alot better with it. Also the primary effect for me is thoughts verbalisation, so i can clearly and easily express what i mean. I already know what ill say the sentence after the next sentence after the next sentence...this really help in social interaction and overall ease of learning.

#8 csrpj

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Posted 18 September 2009 - 12:14 AM

interesting, mdma. i've had similar experiences with verbal control. how long did it take to start working, and how much were you taking? so you're saying you feel an increase in function around-the-clock even if you're not "on" it?

#9 nito

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Posted 18 September 2009 - 03:48 AM

Piracetam sounds almost too good not to try it. I'm sure it will be hard finding the correct dose, and this might put people of continuing with it.
I guess you gotta be patient and try your luck. It's cheap so i don't see the reason not too. And if it does make you foggy i guess u can quit and supplement with lots of choline on its on. Hope i made sense.

#10 acantelopepope

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Posted 18 September 2009 - 06:27 AM

Piracetam sounds almost too good not to try it. I'm sure it will be hard finding the correct dose, and this might put people of continuing with it.
I guess you gotta be patient and try your luck. It's cheap so i don't see the reason not too. And if it does make you foggy i guess u can quit and supplement with lots of choline on its on. Hope i made sense.



I may be posting in more detail on this in the future, but I think that manufacturer and storage procedures have a LOT more to do with Piracetam's efficacy than it's particular efficacy within individuals...

Whether you are getting noticable (and they are noticable) benefits from Piracetam or not, PLEASE POST YOUR SOURCE. For example, I think that PrimaForce is absolute SHIT. When I changed from PrimaForce piracetam to NutraceuticsRx it was like night and day... and I mean this completely. From confusion to clarity. Of course, there are plenty of other variables, but it's time the nootropics community start drawing the line when it comes to quality... the first step is becoming aware of patterns in efficacy among brands.
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#11 csrpj

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Posted 18 September 2009 - 06:43 AM

Piracetam sounds almost too good not to try it. I'm sure it will be hard finding the correct dose, and this might put people of continuing with it.
I guess you gotta be patient and try your luck. It's cheap so i don't see the reason not too. And if it does make you foggy i guess u can quit and supplement with lots of choline on its on. Hope i made sense.



I may be posting in more detail on this in the future, but I think that manufacturer and storage procedures have a LOT more to do with Piracetam's efficacy than it's particular efficacy within individuals...

Whether you are getting noticable (and they are noticable) benefits from Piracetam or not, PLEASE POST YOUR SOURCE. For example, I think that PrimaForce is absolute SHIT. When I changed from PrimaForce piracetam to NutraceuticsRx it was like night and day... and I mean this completely. From confusion to clarity. Of course, there are plenty of other variables, but it's time the nootropics community start drawing the line when it comes to quality... the first step is becoming aware of patterns in efficacy among brands.


real interesting - can anybody confirm this?
i'm actually using primaforce, and i'm having great results.

#12 Vultures

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Posted 18 September 2009 - 12:26 PM

Whether you are getting noticable (and they are noticable) benefits from Piracetam or not, PLEASE POST YOUR SOURCE. For example, I think that PrimaForce is absolute SHIT. When I changed from PrimaForce piracetam to NutraceuticsRx it was like night and day... and I mean this completely. From confusion to clarity. Of course, there are plenty of other variables, but it's time the nootropics community start drawing the line when it comes to quality... the first step is becoming aware of patterns in efficacy among brands.


I've been taking UCB Nootropil from local pharmacy for several months, I also have a bucket of NRx product, but haven't tried it yet (taking a break from nootropics now). It will be intresing to compare those, UCB is supposed to be superior...

Edited by Vultures, 18 September 2009 - 12:27 PM.


#13 mdma

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Posted 18 September 2009 - 04:31 PM

Nubrain and Life-Link both have good quality. Nubrain ships you a Cognitive Nutrition bottle while LifeLink has their own brand. If you go with LifeLink expect a 6weeks shipping period since they seem to be out of everything all the time. You ll save money anyway so i guess its worth the wait.

what i think is interesting with Piracetam is it seems to affects different persons on a different level ( which is logic if no one has similar brains), so it can affect your past memories ( that is scary believe me; some moments, people, came back to me perfectly clear after 10 years +), verbal control, logical thinking ( my school results show it), also intense dreaming is a common effect for me. ( dreams are just different...unusual, but in happy way...the kind of dream u just ask why the hell (and how) did u just dreamt of that).

Anyway, my cup of coffee is done and so is this post...good day to all.

#14 Vultures

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Posted 18 September 2009 - 05:00 PM

Nubrain are a ripoff, they are selling two bottles of Cognitive Nutrition piracetam for 95 USD, whilst its retail price on manufacturer's site is 2x27.99 USD (55.98 USD in total). Here's some info on their practises http://www.imminst.o...WAY-t32191.html

#15 gattaca

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Posted 27 October 2009 - 10:00 PM

I think I can post this here, because he's an imminst sponsor...

I have had very, very noticeable effects while using pete's piracetam, pete of "relentless improvement." He tests the heck out of his stuff, so I trust nobody else, especially after hearing about people ordering tubs full of it from other suppliers which were obviously contaminated.

#16 Pike

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Posted 28 October 2009 - 11:58 AM

i suppose, now that this thread has been bumped, it would be okay to chime in about something somewhat related to the topic:

anybody taking prescription amphetamines would be out of their minds to be coadministering it with piracetam, or any racetam for that manner. piracetam basically puts your NMDA receptors into 6th gear, and glutamate, the body's most abundant excitotoxic neurotransmitter, mediates the entire process of (dopaminergic) stimulant tolerance by opening up the calcium ion channels when it links up with an NMDA receptor. calcium influx is the root of amphetamine tolerance building and i don't doubt that the majority of the tolerance i have now for my prescription amphetamines came from concomitant use of piracetam.

so summed up:

piracetam (induces massive NMDA receptor proliferation in mice) + dopaminergic agents (i.e. amphetamines, wellbutrin, etc.) = neurotoxicity heaven

Edited by Pike, 28 October 2009 - 12:00 PM.


#17 Daytona0blongata

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Posted 18 April 2010 - 07:19 PM

*Bump*
I think what the original poster was asking (which I believe to be a more interesting and prevalent question), is if piracetam has any positive/ negative long term effects. I have been searching the forums for quite some time now and have observed many of the same inquiries, but no concrete answers. Since it seems that there have not been many studies on the after effects of piracetam (such as LTP), I was wondering if anyone had any anecdotal responses- such as effects once dosage stops after long term chronic administration.

#18 Daytona0blongata

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Posted 18 April 2010 - 07:19 PM

*Bump*
I think what the original poster was asking (which I believe to be a more interesting and prevalent question), is if piracetam has any positive/ negative long term effects. I have been searching the forums for quite some time now and have observed many of the same inquiries, but no concrete answers. Since it seems that there have not been many studies on the after effects of piracetam (such as LTP), I was wondering if anyone had any anecdotal responses- such as effects once dosage stops after long term chronic administration.

#19 Daytona0blongata

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Posted 19 April 2010 - 11:08 PM

*Bump*

#20 LabRat84

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Posted 19 April 2010 - 11:59 PM

i suppose, now that this thread has been bumped, it would be okay to chime in about something somewhat related to the topic:

anybody taking prescription amphetamines would be out of their minds to be coadministering it with piracetam, or any racetam for that manner. piracetam basically puts your NMDA receptors into 6th gear, and glutamate, the body's most abundant excitotoxic neurotransmitter, mediates the entire process of (dopaminergic) stimulant tolerance by opening up the calcium ion channels when it links up with an NMDA receptor. calcium influx is the root of amphetamine tolerance building and i don't doubt that the majority of the tolerance i have now for my prescription amphetamines came from concomitant use of piracetam.

so summed up:

piracetam (induces massive NMDA receptor proliferation in mice) + dopaminergic agents (i.e. amphetamines, wellbutrin, etc.) = neurotoxicity heaven


It's a little more complicated than that. First of all, the claim that amphetamine tolerance is caused by excessive calcium influx might not be accurate (excessive calcium influx certainly DOES cause neurotoxicity). Secondly, the NMDA receptor is also modulated by magnesium (voltage-dependent block: prevents it from opening when it's ready), Glycine/D-Serine (which are required co-agonists) and zinc (noncompetitive voltage-independent inhibitor). The famous thread that's been circulating about reversing amphetamine tolerance doesn't fully reflect the complexity of the NMDA receptor. Finally, calcium is not the only ion that flows through the NMDA receptor.

D-serine has been shown to enhance synaptic plasticity in patients with schizophrenia. (I learned about this in a lecture.) It binds to the channel stronger than glycine.

Memantine is an NMDA channel blocker which seems to take the place of magnesium - it also binds in a voltage-dependent manner, allowing the channel to be activated when it's colocalized with other glutamate receptors.

Dextromethorphan and ketamine are voltage-independent channel blockers. They don't "modulate" the receptor and flow of ions, they just block it.

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#21 tea76

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Posted 11 December 2012 - 01:46 PM

Very interesting discussion above. But for us that aren't nearly enough educated in brain chemistry, what does this all mean?
That Piracetam might be dangerous (neurotoxin) or that the combination of amphetamines + piracetam is?

Also, considering the involvement of calcium and magnesium, should I supplement with these two for my Piracetam regimen to function well?




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