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heavy metal and contaminant assays


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#1 acantelopepope

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Posted 25 September 2009 - 01:11 AM


Here are the COAs I received when I asked a company to provide them.

Aniracetam



CERTIFICAE OF ANALYSIS

Product name: Aniracetam
Batch No.: 20090617 Mfg Date: June 17, 2009
Quantity: 500kgs Exp Date: June 16, 2011

Test items Specification Test results
Appearance White crystalline substance Complies
Melting Point 119.0℃~122.0℃ 120.0℃~120.8℃
Absorbance 476~506 489
Chlorides 0.014% Complies
Sulfates 0.04% Complies
Loss on Drying ≤0.5% 0.39%
Related Substances ≤1.0% 0.03%
Sulfated Ash ≤0.1% 0.05%
Heavy Metals <20ppm Complies
Assay 98.0%~101% 99.69%

Conclusion: It meets the requirements of SFDA of China.

Tested by: Top Health QC-01 Checked by: Top Health QC-02

Date: June 17, 2009


Piracetam



CERTIFICAE OF ANALYSIS

Product name: Piracetam
Batch No.: 20090703 Mfg Date: Jul.03, 2009
Quantity: 10kg Exp Date: Jul.02, 2011

Test items Specification Test results
Appearance White or almost white powder Complies
Identification Complies with the infrared absorptions
of RS Complies
Clarity and color
of the solution Should be clear and colorless Complies
Loss on Drying ≤1.0% 0.2%
Residue on ignition ≤0.1% 0.05%
Heavy metal ≤10ppm Pass
Related substance Single impurity:≤0.1%
Total impurity: ≤0.3% 0.06%
0.21%
O.V.I
Isopropanol ≤2000ppm Complies
Methanol ≤1500ppm Complies
Assay Containing 98.0%~102.0% of C6H10N2O2 100.4%

Conclusion: It meets the requirement of EP6.0.

Tested by: He Qing Hua Checked by: Wu Rong Ruan

Date: Apr.22, 2009


I wanted to make these public because I've been meaning to check on the "safe" ranges for the substances listed but have just been too damn busy with school. Maybe someone already knows, or will pursue this more vigorously.

Honestly, I'm just happy that this provider supplied me a detailed COA at all... it seems like too much to ask of many these days.

Also, I really don't know much about heavy metal contamination over long periods of time, but if the only thing these guys are testing for is heavy metal content under 20ppm, that means that a sample could contain 19ppm and it would receive a "pass." Correct me if i'm wrong, but ingesting 19ppm of heavy metals on a daily basis sounds like a no-no.

#2 Rational Madman

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Posted 25 September 2009 - 02:17 AM

Here are the COAs I received when I asked a company to provide them.

Aniracetam



CERTIFICAE OF ANALYSIS

Product name: Aniracetam
Batch No.: 20090617 Mfg Date: June 17, 2009
Quantity: 500kgs Exp Date: June 16, 2011

Test items Specification Test results
Appearance White crystalline substance Complies
Melting Point 119.0℃~122.0℃ 120.0℃~120.8℃
Absorbance 476~506 489
Chlorides 0.014% Complies
Sulfates 0.04% Complies
Loss on Drying ≤0.5% 0.39%
Related Substances ≤1.0% 0.03%
Sulfated Ash ≤0.1% 0.05%
Heavy Metals <20ppm Complies
Assay 98.0%~101% 99.69%

Conclusion: It meets the requirements of SFDA of China.

Tested by: Top Health QC-01 Checked by: Top Health QC-02

Date: June 17, 2009


Piracetam



CERTIFICAE OF ANALYSIS

Product name: Piracetam
Batch No.: 20090703 Mfg Date: Jul.03, 2009
Quantity: 10kg Exp Date: Jul.02, 2011

Test items Specification Test results
Appearance White or almost white powder Complies
Identification Complies with the infrared absorptions
of RS Complies
Clarity and color
of the solution Should be clear and colorless Complies
Loss on Drying ≤1.0% 0.2%
Residue on ignition ≤0.1% 0.05%
Heavy metal ≤10ppm Pass
Related substance Single impurity:≤0.1%
Total impurity: ≤0.3% 0.06%
0.21%
O.V.I
Isopropanol ≤2000ppm Complies
Methanol ≤1500ppm Complies
Assay Containing 98.0%~102.0% of C6H10N2O2 100.4%

Conclusion: It meets the requirement of EP6.0.

Tested by: He Qing Hua Checked by: Wu Rong Ruan

Date: Apr.22, 2009


I wanted to make these public because I've been meaning to check on the "safe" ranges for the substances listed but have just been too damn busy with school. Maybe someone already knows, or will pursue this more vigorously.

Honestly, I'm just happy that this provider supplied me a detailed COA at all... it seems like too much to ask of many these days.

Also, I really don't know much about heavy metal contamination over long periods of time, but if the only thing these guys are testing for is heavy metal content under 20ppm, that means that a sample could contain 19ppm and it would receive a "pass." Correct me if i'm wrong, but ingesting 19ppm of heavy metals on a daily basis sounds like a no-no.

If you're looking for a cognitive enhancement supplement, I think it would be much safer to take Ortho-Mind or Cognitex, which are produced by companies that subject their products to high standards of safety. Since most research on the administration of -racetams that I've encountered is either dated or inadequate in some way, I would limit your use to select occasions. With the added risk of contamination, and because most distributors have a dubious reputation or have attracted controversy in some way, I see no reason why anyone should take -racetams everyday with high confidence.

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#3 acantelopepope

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Posted 04 October 2009 - 04:05 AM

I would agree with you, but many MANY people are taking racetams daily, often many times per day. So is 19ppm heavy metals unacceptable, if this assay is to be trusted at all?




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