it says someone you shouldn't take beta-blockers while taking wellbutrin, but a relitavily knowledge friend looked this up and told me wellbutrin just increases the beta-blocker's effect and to just take less. should i be cautious w/ this combo?
ok to have lower-than-regular dose of propranolol if taking wellbutrin
Started by
csrpj
, Oct 22 2009 02:10 AM
2 replies to this topic
#1
Posted 22 October 2009 - 02:10 AM
it says someone you shouldn't take beta-blockers while taking wellbutrin, but a relitavily knowledge friend looked this up and told me wellbutrin just increases the beta-blocker's effect and to just take less. should i be cautious w/ this combo?
#2
Posted 22 October 2009 - 05:38 AM
if it's contraindicated, don't take it. simple as that.
#3
Posted 22 October 2009 - 05:49 AM
it says someone you shouldn't take beta-blockers while taking wellbutrin, but a relitavily knowledge friend looked this up and told me wellbutrin just increases the beta-blocker's effect and to just take less. should i be cautious w/ this combo?
Well I don't know what your friend was talking about. Wellbutrin boosts norepinephrine and dopamine. norepinephrine is a major stimulator of beta and alpha adrenergic receptors. Beta blockers like propranolol block beta adrenergic receptors (hence their name), and some alpha-adrenergic receptors. So those two drugs are directly counteracting each other. If you take both at the same time you'll get a dopamine boost, but your propranolol will cancel out much of the wellbutrin's norepinephrine effects, especially because propranolol is so non-specific. I don't know who would have prescribed both of those to you. But if you legitimately need both, you should probably go back and get a more specific beta-blocker, depending on what you're taking it for.
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