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l-phenylalanine vs d-phenylalinine


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#1 protoject

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Posted 23 October 2009 - 08:23 AM


To your knowledge, what is the difference between these two isomers in terms of their effects? Can anybody link me up with some good knowledge or research regarding the two?

The only information I could find is that D is a different enantiomer than L; that D is synthetic, and that L can be derived from D . ? . Still looking but I know a lot of you peeps are caught up on your stuff so I'd appreciate anything thrown my way cause I'm pulling up pretty much nothing so far.

#2 pycnogenol

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Posted 23 October 2009 - 11:05 PM

Ray Sahelian has a page about phenylalanine:

http://www.raysaheli...nylalanine.html

[I personally do not take phenylalanine]

Edited by pycnogenol, 23 October 2009 - 11:05 PM.


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#3 protoject

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Posted 26 October 2009 - 04:19 AM

Alright, this is what I've got so far. I'll update if I find anything interesting.

d/l phenylalanine notes


D- a fraction of it breaks down into L.

D- analgesic properties due to blocking the enzyme that breaks

down enkephalin [endorphins]

D- a non-protein amino acid- does not participate in protein

biosynthesis. However, it may be found in some protein foods that

have been processed or aged.


L- precursor to Dopamine, norepinephrine and epinephrine

[adrenaline]

L- precursor to tyrosine

L- building block of proteins

L- Crosses BBB more efficiently than the D isomer.

L- uses the same active transport channel as tryptophan to cross

the BBB, in large quantities phenylalanine interferes with the

production of serotonin, which is a metabolic product of tryptophan

random.
Lignin is derived from phenylalanine and from tyrosine.


---------
FOODS
w/ phenylalinine:
Phenylalanine is contained in most protein-rich foods. Especially

good sources are dairy products (curd, milk, cottage cheese),

avocados, pulses and legumes (particularly peanuts and lima beans),

nuts (pistachios, almonds), seeds (piyal seeds), leafy vegetables,

whole grains, poultry, fish, other seafoods, and some diet

beverages.

breast milk, meat, chicken, fish, nuts, cheese, and other dairy

products. Starchy foods such as potatoes, bread, pasta, and corn

must be monitored. Many diet foods and diet soft drinks that

contain the sweetener aspartame must also be avoided, as aspartame

consists of two amino acids: phenylalanine and aspartic acid.

--
Diseases
phenylketonurina. occurs because l-pa is not converted into

tyrosine by Phenylalanine hydroxylase.




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