8 replies to this topic

[Davevanza]

I read somewhere that Aniracetam is fat soluble.....(or maybe I'm wrong...)

As I know not all Racetams have the same effects in our bodies.

I tried Levetiracetam, which is an anticonvulsant, and it made me feel so sleepy, disoriented, irritable, and I developed tics.

I think Aniracetam affects other neurotransmitters other than Muscarinic-Cholinergic transmitter, such as Dopamine-2, ampakines, etc.

As nicotine initially stimulates Nicotinic-Cholinergic transmitter, then blocks it afterwards ( that's how a cigarette initially stimulates the CNS then relaxes our CNS afterwards ).

Piracetam works via Muscarinic-Cholinergic transmitter ( via Acetyl-choline that we get and formed from Choline ).

As Aniracetam affects Dopamine-2, ( that's how antipsychotics like Haloperidol, Aripiprazole, etc. that treats Schizophrenia ), it blocks our movement system, causing movement disorder called Tardive Dyskinesia, as usually seen from people suffering delusions taking antipsychotics. Not only that, I think Aniracetam also affects other neurotransmitters in our bodies.

It becomes clear, that no wonders Aniracetam when taken with Piracetam, causes reaction that affects our movement peripherally, also centrally it blocks the Dopamine-2 in our brain, which could decrease our creativity.

( The purpose antipsychotics is developed, is to antagonise the effect of drugs such as Amphetamines, Methylphenidate, or anything whether it be a stimulant or a downer that increases the Dopamine in our brain, as Dopamine, centrally creates the "good feeling" from the substance that we take, or in simple terms, it blocks it.)

Personally i have never tried Aniracetam.

Share it here anyone who has been taking Aniracetam for a long term. It's very interesting.

[Johann]

As Aniracetam affects Dopamine-2, ( that's how antipsychotics like Haloperidol, Aripiprazole, etc. that treats Schizophrenia ), it blocks our movement system, causing movement disorder called Tardive Dyskinesia, as usually seen from people suffering delusions taking antipsychotics. Not only that, I think Aniracetam also affects other neurotransmitters in our bodies.

(emphasis Johann)




Aniracetam causes Tardive Dyskinesia?   That is a bold claim.  

[Viscid]

As Aniracetam affects Dopamine-2, ( that's how antipsychotics like Haloperidol, Aripiprazole, etc. that treats Schizophrenia ), it blocks our movement system, causing movement disorder called Tardive Dyskinesia, as usually seen from people suffering delusions taking antipsychotics. Not only that, I think Aniracetam also affects other neurotransmitters in our bodies.

(emphasis Johann)




Aniracetam causes Tardive Dyskinesia? That is a bold claim.

Eating also affects the D2 receptor. I suppose that means eating causes Tardive Dyskinesia.

[KimberCT]

I read somewhere that Aniracetam is fat soluble.....(or maybe I'm wrong...)

As I know not all Racetams have the same effects in our bodies.

I tried Levetiracetam, which is an anticonvulsant, and it made me feel so sleepy, disoriented, irritable, and I developed tics.

I think Aniracetam affects other neurotransmitters other than Muscarinic-Cholinergic transmitter, such as Dopamine-2, ampakines, etc.

As nicotine initially stimulates Nicotinic-Cholinergic transmitter, then blocks it afterwards ( that's how a cigarette initially stimulates the CNS then relaxes our CNS afterwards ).

Piracetam works via Muscarinic-Cholinergic transmitter ( via Acetyl-choline that we get and formed from Choline ).

As Aniracetam affects Dopamine-2, ( that's how antipsychotics like Haloperidol, Aripiprazole, etc. that treats Schizophrenia ), it blocks our movement system, causing movement disorder called Tardive Dyskinesia, as usually seen from people suffering delusions taking antipsychotics. Not only that, I think Aniracetam also affects other neurotransmitters in our bodies.

It becomes clear, that no wonders Aniracetam when taken with Piracetam, causes reaction that affects our movement peripherally, also centrally it blocks the Dopamine-2 in our brain, which could decrease our creativity.

( The purpose antipsychotics is developed, is to antagonise the effect of drugs such as Amphetamines, Methylphenidate, or anything whether it be a stimulant or a downer that increases the Dopamine in our brain, as Dopamine, centrally creates the "good feeling" from the substance that we take, or in simple terms, it blocks it.)

Personally i have never tried Aniracetam.

Share it here anyone who has been taking Aniracetam for a long term. It's very interesting.

I'm pretty sure aniracetam is a D2 agonist, which is why it's action is blocked by D2 antagonists like haloperidol. No need to worry about tardive dyskinesia with D2 agonists... they are actually used as a treatment for movement disorders.

Edited by KimberCT, 24 October 2009 - 09:27 PM.

[sunshinefrost]

i take a micro-doze 1h before playing hockey and it improved my performance dramatically. My game vision and timing is way better and i don't feel the pressures of the need to perform.

[425runner]

I agree about the microdose, strangely enough that's what seems to be most effective for me as well. I took 1/4 of teaspoon yesterday around 4 pm and was totally awake till around midnight, it was very different than when I take 1/2 or 3/4 of teaspoon which makes me "foggy" and sleepy. I guess it has to do with the GABA receptors.

i take a micro-doze 1h before playing hockey and it improved my performance dramatically. My game vision and timing is way better and i don't feel the pressures of the need to perform.

[Metacognition]

I'd be interested to hear more about your claims that aniracetam affects dopamine-2. Where did you find this information? Could you site some sources?

[Davevanza]

I read somewhere that Aniracetam is fat soluble.....(or maybe I'm wrong...)

As I know not all Racetams have the same effects in our bodies.

I tried Levetiracetam, which is an anticonvulsant, and it made me feel so sleepy, disoriented, irritable, and I developed tics.

I think Aniracetam affects other neurotransmitters other than Muscarinic-Cholinergic transmitter, such as Dopamine-2, ampakines, etc.

As nicotine initially stimulates Nicotinic-Cholinergic transmitter, then blocks it afterwards ( that's how a cigarette initially stimulates the CNS then relaxes our CNS afterwards ).

Piracetam works via Muscarinic-Cholinergic transmitter ( via Acetyl-choline that we get and formed from Choline ).

As Aniracetam affects Dopamine-2, ( that's how antipsychotics like Haloperidol, Aripiprazole, etc. that treats Schizophrenia ), it blocks our movement system, causing movement disorder called Tardive Dyskinesia, as usually seen from people suffering delusions taking antipsychotics. Not only that, I think Aniracetam also affects other neurotransmitters in our bodies.

It becomes clear, that no wonders Aniracetam when taken with Piracetam, causes reaction that affects our movement peripherally, also centrally it blocks the Dopamine-2 in our brain, which could decrease our creativity.

( The purpose antipsychotics is developed, is to antagonise the effect of drugs such as Amphetamines, Methylphenidate, or anything whether it be a stimulant or a downer that increases the Dopamine in our brain, as Dopamine, centrally creates the "good feeling" from the substance that we take, or in simple terms, it blocks it.)

Personally i have never tried Aniracetam.

Share it here anyone who has been taking Aniracetam for a long term. It's very interesting.

I'm pretty sure aniracetam is a D2 agonist, which is why it's action is blocked by D2 antagonists like haloperidol. No need to worry about tardive dyskinesia with D2 agonists... they are actually used as a treatment for movement disorders.

Thanks... I think you make it clear that Aniracetam is a D-2 agonist, I was wrong when I wrote it was D-2 antagonise.

Btw, some people report of having a foggy feeling when taking a higher dose of Aniracetam, I guess because Aniracetam affects Serotonergic system, which in that case, Aniracetam is reputed to have an anxiolytic effect.

In psychiatry, besides Benzodiazepines ( Valium, Ativan, etc.) which affect GABA-B or Benzodiazepine receptor, there are also some antidepressants ( SSRI's, SNRI's : Paxil, Effexor, etc.) which work via Serotonergic system, which have anxiolytic effect. An atypical novel medication like Buspar ( buspirone) also partly works via Serotonin sub type 1A to exert its anxiolytic effect. This way confirms that Aniracetam has an anxiolytic effect, via Serotonin Antagonise, as well as nootropic effect.

[Johann]

 No, the fogginess comes from acetylcholine depletion.  But that is dealt with by 

taking choline.