anyone have any input on forms? the two most well researched i know of are chromemate polynicotinate and chromium 454... right now im leaning towards chromium 454
L
onge
C
ity
Advocacy & Research for Unlimited Lifespans
Posted 05 November 2009 - 02:41 AM
Posted 05 November 2009 - 03:21 AM
anyone have any input on forms? the two most well researched i know of are chromemate polynicotinate and chromium 454... right now im leaning towards chromium 454
Posted 05 November 2009 - 03:38 AM
I read that plynicotinate is Chromium picolinate is chromium III processed with picolinic acid. Picolinic acid is used in herbicides.
Not sure if that is true or not.
Posted 05 November 2009 - 03:43 AM
Edited by Blue, 05 November 2009 - 03:47 AM.
Posted 05 November 2009 - 09:01 AM
Posted 05 November 2009 - 06:51 PM
There seems to be only one, likely manufacturer sponsored, rat study on chromium 454. The manufacturer also mentions a cell studie which is less interesting. No human studies. Also, it is a brewer's yeast extract. Brewer's yeast contains a lot of things that may have unclear and unknown metabolic effects and thus I think should be avoided in a basic multi.
http://scholar.googl...="chromium 454"
Another alternative to the by far most researched chromium picolinate is chromium niacinate:
http://www.sciencedi...14e5b1ecb65a890
http://www.lieberton...9/ars.2007.1577
Posted 24 November 2009 - 04:10 AM
Posted 24 November 2009 - 05:19 AM
Comparing metabolic effects of six different commercial trivalent chromium compounds.
Preuss HG, Echard B, Perricone NV, Bagchi D, Yasmin T, Stohs SJ.
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, United States. preusshg@georgetown.edu
Recent reports provide cogent evidence that the average individual becomes chromium deficient with age. Unfortunately, chromium deficiency is strongly associated with many aspects of the Metabolic Syndrome, including insulin resistance and type 2 diabetes. Since replacement of chromium, per os, often ameliorates many deleterious manifestations associated with insulin resistance and diabetes, it is not surprising that many different, commercial trivalent chromium compounds are available on the market. However, previous reports have shown that the form of trivalent chromium (negative charges) can influence effectiveness markedly. We compared various commercial forms of trivalent chromium commonly used alone or in formulations, to examine whether they are equally effective and non-toxic. In the first study, five different chromium products were examined - citrate, amino acid chelate (AAC), chelavite, polynicotinate (NBC), and nicotinate. In the second study, effects of NBC and picolinate were assessed. Results demonstrated that only chelavite and NBC improved insulin sensitivity, and only NBC decreased systolic blood pressure (SBP) significantly. In the second study, both picolinate and NBC significantly decreased SBP compared to control. NBC and picolinate decreased malonyldialdehyde concentrations (free radical formation) and DNA fragmentation in hepatic and renal tissues. No evidence of adverse effects was noted with any of the compounds tested. In conclusion, while all the trivalent chromium compounds tested seem safe, only three enhanced insulin sensitivity (NBC, chelavite, and picolinate) and only two decreased SBP significantly (NBC and picolinate). Furthermore, both NBC and picolinate were protective in lessening free radical formation and DNA damage in the liver and kidneys.
Edited by ajnast4r, 24 November 2009 - 05:23 AM.
Posted 24 November 2009 - 08:55 AM
Posted 24 November 2009 - 11:22 AM
Interesting. Not stated clearly but probably an animal study. But I thought that polynicotinate and nicotinate was the same? At least Chromemate claims that.http://www.sciencedi...d236b1c1eff1dcc
Comparing metabolic effects of six different commercial trivalent chromium compounds.
Preuss HG, Echard B, Perricone NV, Bagchi D, Yasmin T, Stohs SJ.
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, United States. preusshg@georgetown.edu
Recent reports provide cogent evidence that the average individual becomes chromium deficient with age. Unfortunately, chromium deficiency is strongly associated with many aspects of the Metabolic Syndrome, including insulin resistance and type 2 diabetes. Since replacement of chromium, per os, often ameliorates many deleterious manifestations associated with insulin resistance and diabetes, it is not surprising that many different, commercial trivalent chromium compounds are available on the market. However, previous reports have shown that the form of trivalent chromium (negative charges) can influence effectiveness markedly. We compared various commercial forms of trivalent chromium commonly used alone or in formulations, to examine whether they are equally effective and non-toxic. In the first study, five different chromium products were examined - citrate, amino acid chelate (AAC), chelavite, polynicotinate (NBC), and nicotinate. In the second study, effects of NBC and picolinate were assessed. Results demonstrated that only chelavite and NBC improved insulin sensitivity, and only NBC decreased systolic blood pressure (SBP) significantly. In the second study, both picolinate and NBC significantly decreased SBP compared to control. NBC and picolinate decreased malonyldialdehyde concentrations (free radical formation) and DNA fragmentation in hepatic and renal tissues. No evidence of adverse effects was noted with any of the compounds tested. In conclusion, while all the trivalent chromium compounds tested seem safe, only three enhanced insulin sensitivity (NBC, chelavite, and picolinate) and only two decreased SBP significantly (NBC and picolinate). Furthermore, both NBC and picolinate were protective in lessening free radical formation and DNA damage in the liver and kidneys.
Posted 24 November 2009 - 12:20 PM
Edited by Blue, 24 November 2009 - 12:21 PM.
Posted 24 November 2009 - 12:40 PM
0 members, 1 guests, 0 anonymous users