Curious to see the forms and dosages you guys are considering for everything now. Keep us posted in this thread as it changes, please.
L
onge
C
ity
Advocacy & Research for Unlimited Lifespans
Posted 01 December 2009 - 06:28 AM
Posted 01 December 2009 - 05:07 PM
Curious to see the forms and dosages you guys are considering for everything now. Keep us posted in this thread as it changes, please.
Posted 01 December 2009 - 05:35 PM
Posted 02 December 2009 - 03:44 PM
It's password protected so we can't see it. :-(Shazam, you might have missed this thread, where the final design is being discussed.
Posted 04 December 2009 - 05:05 AM
Shazam, you might have missed this thread, where the final design is being discussed.
Posted 04 December 2009 - 05:29 AM
Posted 06 December 2009 - 03:57 AM
I'm not sure what the permissions are on that thread. Members only, maybe? I didn't realize it was protected.
Here is the current design in a spreadsheet. Once the design is finalized, the manufacturer would have to acquire each ingredient, have them tested, schedule a run at the capping plant, and have it done. Other things would include finalizing the labels, with text and art, and having them printed. From the point of design finalization, I would expect the wait for a finished product to be measured in months rather than years, but I've never taken a product to market before. My experience is earlier in the pharmaceutical R&D pipeline.
Posted 06 December 2009 - 04:52 AM
The design philosophy behind this multi might be called "First, do no harm." The reason we are doing this is because we can't find a single multi on the market that we can recommend without hesitation. The usual problem is not underdoses, but overdoses. I'm all for exceeding the RDA on vitamin D, but in general, there is a lot of science behind the RDA, and it is pretty reasonable. Anyone who wants more of something can always add it, but if you want less, you are stuck; you can't subtract one component. A multi is not meant to provide a therapeutic quantity of anything, only to prevent deficiency. We may have left this philosophy behind on choline, but otherwise, that's what we are trying to do. We are actually being very skeptical here, because we are going against the design of perhaps every multi on the market. I am now of the opinion that most of them, with rare exceptions, are designed more with marketing in mind than health. The number one marketing claim? "We have way more of everything than the competition!" Our claim is the opposite. "We have way less of most things than all the supplements designed by marketers. We use only the best available forms and are scrupulous about purity." Another design theme that I think is behind this project is that it's meant to be a multi for people who really care about their health, and are already eating a halfway decent diet. It's not meant to be a rescue pill for people living on Red Bull and Big Macs. (Although it would probably work better for that than some multis...) It's also not meant to be the only supplement you'll ever need. People's needs are too different for that to work well.Cool on both counts. Cool on the first because it will revive discussion (my feedback is in the file now, I'd like some responses, either in the file in column E or on this thread if possible.).I'm not sure what the permissions are on that thread. Members only, maybe? I didn't realize it was protected.
Here is the current design in a spreadsheet. Once the design is finalized, the manufacturer would have to acquire each ingredient, have them tested, schedule a run at the capping plant, and have it done. Other things would include finalizing the labels, with text and art, and having them printed. From the point of design finalization, I would expect the wait for a finished product to be measured in months rather than years, but I've never taken a product to market before. My experience is earlier in the pharmaceutical R&D pipeline.
Cool on the second count because that means there is no rush in our (vital) design process if we wanna see this by spring. So let's really put the magnifying glass to these amounts and forms. Let's not be cynics ("I don't believe it unless it's completely concretely proven" attitude, and sticking to the potentially overly conservative RDA until it's so obvious that you can't deny it.), but skeptics (challenging the RDA where it needs to be challenged, intelligent conjecture, and intensive research as a community).
Posted 06 December 2009 - 05:30 AM
The design philosophy behind this multi might be called "First, do no harm." The reason we are doing this is because we can't find a single multi on the market that we can recommend without hesitation. The usual problem is not underdoses, but overdoses. I'm all for exceeding the RDA on vitamin D, but in general, there is a lot of science behind the RDA, and it is pretty reasonable. Anyone who wants more of something can always add it, but if you want less, you are stuck; you can't subtract one component. A multi is not meant to provide a therapeutic quantity of anything, only to prevent deficiency. We may have left this philosophy behind on choline, but otherwise, that's what we are trying to do. We are actually being very skeptical here, because we are going against the design of perhaps every multi on the market. I am now of the opinion that most of them, with rare exceptions, are designed more with marketing in mind than health. The number one marketing claim? "We have way more of everything than the competition!" Our claim is the opposite. "We have way less of most things than all the supplements designed by marketers. We use only the best available forms and are scrupulous about purity." Another design theme that I think is behind this project is that it's meant to be a multi for people who really care about their health, and are already eating a halfway decent diet. It's not meant to be a rescue pill for people living on Red Bull and Big Macs. (Although it would probably work better for that than some multis...) It's also not meant to be the only supplement you'll ever need. People's needs are too different for that to work well.Cool on both counts. Cool on the first because it will revive discussion (my feedback is in the file now, I'd like some responses, either in the file in column E or on this thread if possible.).I'm not sure what the permissions are on that thread. Members only, maybe? I didn't realize it was protected.
Here is the current design in a spreadsheet. Once the design is finalized, the manufacturer would have to acquire each ingredient, have them tested, schedule a run at the capping plant, and have it done. Other things would include finalizing the labels, with text and art, and having them printed. From the point of design finalization, I would expect the wait for a finished product to be measured in months rather than years, but I've never taken a product to market before. My experience is earlier in the pharmaceutical R&D pipeline.
Cool on the second count because that means there is no rush in our (vital) design process if we wanna see this by spring. So let's really put the magnifying glass to these amounts and forms. Let's not be cynics ("I don't believe it unless it's completely concretely proven" attitude, and sticking to the potentially overly conservative RDA until it's so obvious that you can't deny it.), but skeptics (challenging the RDA where it needs to be challenged, intelligent conjecture, and intensive research as a community).
I don't think the group can carry on a conversation in the spreadsheet, (I didn't even know it was write-enabled.) so we should discuss on the forum.
Edited by shazam, 06 December 2009 - 05:49 AM.
Posted 06 December 2009 - 05:49 AM
Vitamin C is a good example of something that some people will want to supplement in order to get what they consider to be therapeutic amounts of it. I don't want a lot in a multi because I don't want exogenous antioxidants interfering with my workouts. Half a gram of anything is a lot of volume, which is a packaging consideration. These issues really should have been raised in the form and quantity threads. Where am I quoting others?Fair enough, but if you're going to delete my feedback, please quote it here.The design philosophy behind this multi might be called "First, do no harm." The reason we are doing this is because we can't find a single multi on the market that we can recommend without hesitation. The usual problem is not underdoses, but overdoses. I'm all for exceeding the RDA on vitamin D, but in general, there is a lot of science behind the RDA, and it is pretty reasonable. Anyone who wants more of something can always add it, but if you want less, you are stuck; you can't subtract one component. A multi is not meant to provide a therapeutic quantity of anything, only to prevent deficiency. We may have left this philosophy behind on choline, but otherwise, that's what we are trying to do. We are actually being very skeptical here, because we are going against the design of perhaps every multi on the market. I am now of the opinion that most of them, with rare exceptions, are designed more with marketing in mind than health. The number one marketing claim? "We have way more of everything than the competition!" Our claim is the opposite. "We have way less of most things than all the supplements designed by marketers. We use only the best available forms and are scrupulous about purity." Another design theme that I think is behind this project is that it's meant to be a multi for people who really care about their health, and are already eating a halfway decent diet. It's not meant to be a rescue pill for people living on Red Bull and Big Macs. (Although it would probably work better for that than some multis...) It's also not meant to be the only supplement you'll ever need. People's needs are too different for that to work well.Cool on both counts. Cool on the first because it will revive discussion (my feedback is in the file now, I'd like some responses, either in the file in column E or on this thread if possible.).I'm not sure what the permissions are on that thread. Members only, maybe? I didn't realize it was protected.
Here is the current design in a spreadsheet. Once the design is finalized, the manufacturer would have to acquire each ingredient, have them tested, schedule a run at the capping plant, and have it done. Other things would include finalizing the labels, with text and art, and having them printed. From the point of design finalization, I would expect the wait for a finished product to be measured in months rather than years, but I've never taken a product to market before. My experience is earlier in the pharmaceutical R&D pipeline.
Cool on the second count because that means there is no rush in our (vital) design process if we wanna see this by spring. So let's really put the magnifying glass to these amounts and forms. Let's not be cynics ("I don't believe it unless it's completely concretely proven" attitude, and sticking to the potentially overly conservative RDA until it's so obvious that you can't deny it.), but skeptics (challenging the RDA where it needs to be challenged, intelligent conjecture, and intensive research as a community).
I don't think the group can carry on a conversation in the spreadsheet, (I didn't even know it was write-enabled.) so we should discuss on the forum.
Also, in terms of the philosophical rant, I'm not expecting this to be a 'rescue pill' for people living unhealthy lifestyles. There is NO SUCH PILL. But what I am expecting is we not water it down in areas (such as vitamin C and biotin) where one could benefit from a higher dose than the RDA. If you want sources, just do actual research instead of spewing rhetoric. The linus pauling association has enough information on vitamin C for one to extropolate that 500mg is a reasonable dose. There's less evidence for megadosing, but it's clear enough that 90mg is a little low... it's the bare minimum, the shield against acute symptoms, as has been evidenced with vitamin D. If you're worried about pro oxidant effects, leave it at 500mg or below, but 90mg... ^^^^^^.
The problem might not be the same with other vitamins (such as most of the Bs, and retinol/BC... those should be fine with the RDA), but I'm looking at the RDA as the bare minimum, with few exceptions. Some may be higher, for good reasons, some may be lower, for good reasons. Reasonable conjecture or hard evidence. Keeping the copper low is reasonable conjecture backed by some evidence. Keeping the vitamin C low is the polar opposite of that. If somebody wanted to discredit the risk of putting copper in a multi in the same way that people here try to discredit putting moderate dose (500mg+, below 1g) vitamin C in, (through claiming the evidence is not sufficient to make a decision yet despite the evidence being there), then they could.
Applying that same mindset to finding benefits as well as avoiding risks would likely make this multi a better multi. Weigh the risk/reward. Actually look into the sources yourself instead of quoting others... plenty of people who try to discredit the linus pauling studies (of which some have holes) throw the baby out with the bathwater. So see for yourself to the extent that you can... solid research.
Posted 06 December 2009 - 06:07 AM
Vitamin C is a good example of something that some people will want to supplement in order to get what they consider to be therapeutic amounts of it. I don't want a lot in a multi because I don't want exogenous antioxidants interfering with my workouts. Half a gram of anything is a lot of volume, which is a packaging consideration. These issues really should have been raised in the form and quantity threads. Where am I quoting others?Fair enough, but if you're going to delete my feedback, please quote it here.The design philosophy behind this multi might be called "First, do no harm." The reason we are doing this is because we can't find a single multi on the market that we can recommend without hesitation. The usual problem is not underdoses, but overdoses. I'm all for exceeding the RDA on vitamin D, but in general, there is a lot of science behind the RDA, and it is pretty reasonable. Anyone who wants more of something can always add it, but if you want less, you are stuck; you can't subtract one component. A multi is not meant to provide a therapeutic quantity of anything, only to prevent deficiency. We may have left this philosophy behind on choline, but otherwise, that's what we are trying to do. We are actually being very skeptical here, because we are going against the design of perhaps every multi on the market. I am now of the opinion that most of them, with rare exceptions, are designed more with marketing in mind than health. The number one marketing claim? "We have way more of everything than the competition!" Our claim is the opposite. "We have way less of most things than all the supplements designed by marketers. We use only the best available forms and are scrupulous about purity." Another design theme that I think is behind this project is that it's meant to be a multi for people who really care about their health, and are already eating a halfway decent diet. It's not meant to be a rescue pill for people living on Red Bull and Big Macs. (Although it would probably work better for that than some multis...) It's also not meant to be the only supplement you'll ever need. People's needs are too different for that to work well.Cool on both counts. Cool on the first because it will revive discussion (my feedback is in the file now, I'd like some responses, either in the file in column E or on this thread if possible.).I'm not sure what the permissions are on that thread. Members only, maybe? I didn't realize it was protected.
Here is the current design in a spreadsheet. Once the design is finalized, the manufacturer would have to acquire each ingredient, have them tested, schedule a run at the capping plant, and have it done. Other things would include finalizing the labels, with text and art, and having them printed. From the point of design finalization, I would expect the wait for a finished product to be measured in months rather than years, but I've never taken a product to market before. My experience is earlier in the pharmaceutical R&D pipeline.
Cool on the second count because that means there is no rush in our (vital) design process if we wanna see this by spring. So let's really put the magnifying glass to these amounts and forms. Let's not be cynics ("I don't believe it unless it's completely concretely proven" attitude, and sticking to the potentially overly conservative RDA until it's so obvious that you can't deny it.), but skeptics (challenging the RDA where it needs to be challenged, intelligent conjecture, and intensive research as a community).
I don't think the group can carry on a conversation in the spreadsheet, (I didn't even know it was write-enabled.) so we should discuss on the forum.
Also, in terms of the philosophical rant, I'm not expecting this to be a 'rescue pill' for people living unhealthy lifestyles. There is NO SUCH PILL. But what I am expecting is we not water it down in areas (such as vitamin C and biotin) where one could benefit from a higher dose than the RDA. If you want sources, just do actual research instead of spewing rhetoric. The linus pauling association has enough information on vitamin C for one to extropolate that 500mg is a reasonable dose. There's less evidence for megadosing, but it's clear enough that 90mg is a little low... it's the bare minimum, the shield against acute symptoms, as has been evidenced with vitamin D. If you're worried about pro oxidant effects, leave it at 500mg or below, but 90mg... ^^^^^^.
The problem might not be the same with other vitamins (such as most of the Bs, and retinol/BC... those should be fine with the RDA), but I'm looking at the RDA as the bare minimum, with few exceptions. Some may be higher, for good reasons, some may be lower, for good reasons. Reasonable conjecture or hard evidence. Keeping the copper low is reasonable conjecture backed by some evidence. Keeping the vitamin C low is the polar opposite of that. If somebody wanted to discredit the risk of putting copper in a multi in the same way that people here try to discredit putting moderate dose (500mg+, below 1g) vitamin C in, (through claiming the evidence is not sufficient to make a decision yet despite the evidence being there), then they could.
Applying that same mindset to finding benefits as well as avoiding risks would likely make this multi a better multi. Weigh the risk/reward. Actually look into the sources yourself instead of quoting others... plenty of people who try to discredit the linus pauling studies (of which some have holes) throw the baby out with the bathwater. So see for yourself to the extent that you can... solid research.
Edited by shazam, 06 December 2009 - 06:22 AM.
Posted 07 December 2009 - 12:34 AM
The design philosophy behind this multi might be called "First, do no harm." The reason we are doing this is because we can't find a single multi on the market that we can recommend without hesitation. The usual problem is not underdoses, but overdoses.
Edited by resvhead, 07 December 2009 - 12:36 AM.
Posted 07 December 2009 - 01:49 AM
Edited by niner, 07 December 2009 - 01:50 AM.
Posted 07 December 2009 - 05:00 AM
Edited by nameless, 07 December 2009 - 05:01 AM.
Posted 09 December 2009 - 12:01 AM
Posted 09 December 2009 - 04:37 AM
Posted 09 December 2009 - 10:48 AM
Posted 09 December 2009 - 10:59 AM
Posted 09 December 2009 - 01:35 PM
So do we have a rough draft or what? What components seem to be decided on and which ones need more attention?
Posted 17 December 2009 - 10:48 PM
So do we have a rough draft or what? What components seem to be decided on and which ones need more attention?
Here is the spreadsheet link. It's hidden in a post up above:
http://spreadsheets....o...phWGc&hl=en
Edited by ajnast4r, 17 December 2009 - 11:02 PM.
Posted 17 December 2009 - 11:18 PM
So when is the process finished? What are the items we are waiting on?So do we have a rough draft or what? What components seem to be decided on and which ones need more attention?
Here is the spreadsheet link. It's hidden in a post up above:
http://spreadsheets....o...phWGc&hl=en
thats not the current spreadsheet. the current formula will most likely remain private until the process is finished.
i cant figure out why that document still works? it says im the owner but its not in my document list and i cant delete it?
Posted 09 January 2010 - 07:37 AM
Posted 14 January 2010 - 09:46 PM
When will progress on this project resume?
Posted 08 March 2010 - 11:21 PM
Edited by shazam, 08 March 2010 - 11:26 PM.
Posted 04 May 2010 - 06:39 PM
Posted 06 May 2010 - 06:11 PM
Man I wish I could see what's going on in there.
Well, I heard speculations of spring. Spring is getting close to an end.
How are we doing on progress? Any new info? Price quotes, potential form factors, a nutrition info label for the final draft of this iteration of the multi?
Posted 08 May 2010 - 01:32 PM
Posted 08 May 2010 - 07:15 PM
Edited by niner, 08 May 2010 - 07:20 PM.
Posted 08 May 2010 - 10:21 PM
Edited by Anthony_Loera, 08 May 2010 - 10:22 PM.
Posted 09 May 2010 - 10:06 PM
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