Bad to take long-term, right?
Huperzine A
#1
Posted 06 December 2009 - 12:58 PM
Bad to take long-term, right?
#2
Posted 06 December 2009 - 02:03 PM
#3
Posted 06 December 2009 - 02:33 PM
"While it is safe to boost acetylcholine levels by inhibiting acetylcholinesterase periodically, chronic use of Huperzine A could cause over-suppression of acetylcholinesterase and subsequent acetylcholine overload with unknown consequences. Remember, you can take huge amounts of acetylcholine precursors such as choline without fear of acetylcholine overload because you have acetylcholinesterase to degrade excess acetylcholine. If you block the body’s natural regulator of acetylcholine (that regulator being acetylcholinesterease), you may have a problem. We do not recommend that people take Huperzine A more than twice a week, much less promote it for daily use like other companies do."
#4
Posted 06 December 2009 - 05:59 PM
#5
Posted 06 December 2009 - 10:01 PM
I haven't heard that it is too bad, just not as well researched as galantamine. That said, I prefer CDP Choline.
#6
Posted 06 December 2009 - 10:14 PM
I take it once or twice a week not for its cholinesterase blocking effects, but for its effects via brain trophic factors.
#7
Posted 07 December 2009 - 01:48 AM
it also blocks NMDA receptors, making long term memory consolidation more difficult in theory. It produces acute results, basically memory on a lease from my personal experience......
I take it once or twice a week not for its cholinesterase blocking effects, but for its effects via brain trophic factors.
Ah, that's interesting. Does galantamine suffer from the same problem?
Are there any NMDA enhancers?
#8
Posted 07 December 2009 - 08:52 PM
it also blocks NMDA receptors, making long term memory consolidation more difficult in theory. It produces acute results, basically memory on a lease from my personal experience......
I take it once or twice a week not for its cholinesterase blocking effects, but for its effects via brain trophic factors.
Ah, that's interesting. Does galantamine suffer from the same problem?
Are there any NMDA enhancers?
Piracetam primes NMDA receptors, making them more effective. You don't want to juice up NMDA too much, since neurotoxicity is also mediated by overworked NMDA and AMPA receptors....
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