Ok i'm gonna tell you why I think the carbohydrate-induced-obesity is wrong and if this is not enough well I don't know what else to say.
First, why do I think it is important not to fall into this? Because I've counsiled a bunch of people so far at loosing weight and two years ago, after reading GCBC I also thought that calorie did not matter as long as carbs intake was kept low (around 50-80g). What happened to people I told not to care about how much they eat? They binge on cream, dark chocolate, nuts, cheeze and bacon. What happened to their weight? At first they lost about 2-3 pounds (which certainly was only water) and then weight loss plateau. And it was not moving, even if carbs was kept low. When I realised about 1 years ago that this was foolish, I started couting the calorie intake of my client for 1 week, and then having them trying to eat about the same amount of food. And now what is always happening to their weight if they track calorie adequatly? It's always moving down (even if they have 100-200g of carbs).
That's actually in line with this
post of Eades, where he says at the end
So, if you keep carbs low and keep calories in check you will lose weight. If you keep carbs low and don’t worry about the calories you will maintain
Now, the carbohydrate hypothetis put forward by Taubes is that cabrs drive insulin up and insulin makes it impossible to loose fat, and is a powerful fat accumulation messenger. He also says that calorie/in/out are not independant one from another. So if you move more you're likely to eat more and if you eat less you likely to move less (homostatis at work).
The main point of this thread is that carbohydrate drives insulin up and that insulin makes it easy to gain fat/and hard to loose it. How true is this?
First, we can ask ourself if it's an all or nothing mechanism. I mean, is it the more insulin the more fat stored and the less weight lost? If it's the case, that means
a) that any level of insulin would impairs fat loss (and insulin is never at 0, there's always some around in the blood) so it would physiocally be impossible to loose weight and
b) the more high GI the diet, the less weight that would be loss.
a) is pretty easy to understand as not true.
b) let's look at studies.
Many studies have look at the effect of diffrent glycemic index diet on weight loss, and many did not find a difference on weight loss. (
1,
2,
3,
4,
5,
6)
Note that weight loss in these studies was not influence even if there was great variance in insulin level. So caloric restriction is much more important than simply lowering insulin for weight loss.
Now, is it true that a) insulin is the major fat sotring hormone and b) that it really impairs fat loss? Doesn't look like it.
a) Acylation stimulating protein is an hormone that the ONLY role (compare to insulin that has many many) is promoting fat storage.
Is role is at least as important as insulinThere's also
Fat-specific protein 27 that promote fat storage independently of insulin level.
So while it's true that insulin is a big player in fat accumulation, it's certainly not the only one as Taubes implies in his book.
b) Some studies investigated the effect of diazoxide, a drug that inhibits insulin secretion, on weight loss (
1) No effect was seen between the control group and the experimental one. (once again, less insulin doesn't mean more weight lost)
And now, the last question, if there's a metabolic advantage of low-carb diet. As pointed out by Lyle McDonald and Anthony Colpo already, even if on paper it looks like there could be a metabolic advantage, it is worthless to speculate so when we have good studies that have investigated the question and that found it is not the case.
So, as someone pointed out here already, PROTEIN seems to be making a difference. Playing only with carbs and fat don't.
I'll leave you with this excellent study that controlled protein intake and calorie intake and was seeking for a metabolic advantage from low-acrb and that did not find any.
Ketogenic low-carbohydrate diets have no metabolic advantage over nonketogenic low-carbohydrate dietsBACKGROUND: Low-carbohydrate diets may promote greater weight loss than does the conventional low-fat, high-carbohydrate diet. OBJECTIVE: We compared weight loss and biomarker change in adults adhering to a ketogenic low-carbohydrate (KLC) diet or a nonketogenic low-carbohydrate (NLC) diet. DESIGN: Twenty adults [body mass index (in kg/m(2)): 34.4 +/- 1.0] were randomly assigned to the KLC (60% of energy as fat, beginning with approximately 5% of energy as carbohydrate) or NLC (30% of energy as fat; approximately 40% of energy as carbohydrate) diet. During the 6-wk trial, participants were sedentary, and 24-h intakes were strictly controlled. RESULTS: Mean (+/-SE) weight losses (6.3 +/- 0.6 and 7.2 +/- 0.8 kg in KLC and NLC dieters, respectively; P = 0.324) and fat losses (3.4 and 5.5 kg in KLC and NLC dieters, respectively; P = 0.111) did not differ significantly by group after 6 wk. Blood beta-hydroxybutyrate in the KLC dieters was 3.6 times that in the NLC dieters at week 2 (P = 0.018), and LDL cholesterol was directly correlated with blood beta-hydroxybutyrate (r = 0.297, P = 0.025). Overall, insulin sensitivity and resting energy expenditure increased and serum gamma-glutamyltransferase concentrations decreased in both diet groups during the 6-wk trial (P < 0.05). However, inflammatory risk (arachidonic acid:eicosapentaenoic acid ratios in plasma phospholipids) and perceptions of vigor were more adversely affected by the KLC than by the NLC diet. CONCLUSIONS: KLC and NLC diets were equally effective in reducing body weight and insulin resistance, but the KLC diet was associated with several adverse metabolic and emotional effects. The use of ketogenic diets for weight loss is not warranted.
That's in line with many others studies that did not find any difference when protein and calorie are controlled.
I'm not denying Taubes work. He did an awesome job at explaining the political aspect of the low-fat craze. But I don't think the carbohydrate-obesity-hypothesis is supported by current evidence.
Edited by oehaut, 21 December 2009 - 06:13 PM.