should you not take the two at the same time?
also, while i'm at it, any news on weather taking straight ALA (vs R-ALA) is that much inferior to R-ALA?
Posted 10 January 2010 - 03:48 PM
Posted 11 January 2010 - 06:56 AM
Posted 11 January 2010 - 03:23 PM
Posted 11 January 2010 - 05:08 PM
should you not take the two at the same time?
also, while i'm at it, any news on weather taking straight ALA (vs R-ALA) is that much inferior to R-ALA?
Posted 12 January 2010 - 03:45 AM
Posted 12 January 2010 - 03:33 PM
R-LA is the isomer that is synthesized by plants and animals and functions as a cofactor for mitochondrial enzymes in its protein bound form (see Biological Activities). Direct comparisons of the bioavailability of oral racemic LA and R-LA supplements have not been published. After oral dosing with racemic LA, peak plasma concentrations of R-LA were found to be 40-50% higher than S-LA, suggesting R-LA is better absorbed than S-LA, but both isomers are rapidly metabolized and eliminated (12, 14, 15). In rats, R-LA was more effective than S-LA in enhancing insulin-stimulated glucose transport and metabolism in skeletal muscle (44), and R-LA was more effective than racemic LA and S-LA in preventing cataracts (71). However, virtually all of the published studies of LA supplementation in humans have used racemic LA. At present, it is not clear whether R-LA supplements are more effective than racemic LA supplements in humans.
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