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'Longevity Gene' Helps Prevent Memory Decline and Dementia


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#1 babcock

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Posted 14 January 2010 - 01:59 PM


Scientists at Albert Einstein College of Medicine of Yeshiva University have found that a "longevity gene" helps to slow age-related decline in brain function in older adults. Drugs that mimic the gene's effect are now under development, the researchers note, and could help protect against Alzheimer's disease.

"We found that people with two copies of the longevity variant of CETP had slower memory decline and a lower risk for developing dementia and Alzheimer's disease," says Amy E. Sanders, M.D., assistant professor in the Saul R. Korey Department of Neurology at Einstein and lead author of the paper. "More specifically, those participants who carried two copies of the favorable CETP variant had a 70 percent reduction in their risk for developing Alzheimer's disease compared with participants who carried no copies of this gene variant."


http://www.scienceda...00112165234.htm

It will be interesting to see if the "Drugs in development" are able to reproduce the function of carrying the double gene.




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