I will be juice fasting for 2-3weeks to try to alleviate my noise-induced tinnitus that occurred 3 months ago and to detoxify the body in general. I have been on a normal juice fast for a couple of times before without problems. Now I would like to know how safe it is to take some nootropics to treat the tinnitus while fasting? I also need advice on how should I take them, with (fruit or vegetable)juice, herbal tea or without? All pills at the same time or separately?
I would be taking:
- Vinpocetine 10mg x1/day (maybe x2/day on some days)
- ALCAR 500mg x1/day (maybe x2/day on some days)
- NAC 600mg (maybe once or twice a week)
and also:
- Betaserc 24mg x2/day (betahistine, prescribed for tinnitus, I take one in the morning and one before going to sleep)
- Vitamin C 500mg-1g (on some days)
- Chlorella 1 teaspoon/day
Also I haven't found any information on possible interactions of vinpocetine, ALCAR and NAC with Betaserc, but I'd like to know if there possibly are any?
from Wikipedia:
Betahistine has a very strong affinity for histamine H3 receptors and a weak affinity for histamine H1 receptors. Betahistine seems to dilate the blood vessels within the middle ear which can relieve pressure from excess fluid and act on the smooth muscle.
The mode of action of betahistine was believed to be a direct stimulating (agonistic) effect on H1 receptors located on blood vessels in the inner ear. This would give rise to local vasodilation and increased permeability, which would help reverse the underlying problem of endolymphatic hydrops.
In addition, betahistine has a powerful antagonistic effects at H3 receptors, and increases the levels of neurotransmitters released from the nerve endings. This is thought to have two consequences;
The increased amounts of histamine released from histaminergic nerve endings can stimulate H1 receptors, thus augmenting the direct agonistic effects of betahistine on these receptors. This explains the potent vasodilatory effects of betahistine in the inner ear, which are well documented.
It is postulated that betahistine increases the levels of neurotransmitters such as serotonin in the brainstem, which inhibits the activity of vestibular nuclei.
Suggestions of amounts to take these or other supplements to add are also welcome..