LONGECITY

Hi, does anyone have any information about the research in the field of nanotechnology used specifically in order to repair damaged DNA? I am talking about specific examples of nano(machines) that can sense DNA damage and repair it. Thanks

Yes.

The Nanomedicine series by Robert Freitas: http://www.nanomedicine.com/

They build directly on Drexler's work and constructs for nanotechnology. The most relevant book is Volume III which is due in 2012 and focuses on reversing disease and the aging process.
The other volumes (basic capability and biocompatibility) are a pre-requirement, though.

Drexler-like, controllable, nanotechnology does not yet exist, but Drexler has demonstrated unrefuted physicochemical feasibility of his models, upon which Freitas builds his proposals.

Yes.

The Nanomedicine series by Robert Freitas: http://www.nanomedicine.com/

They build directly on Drexler's work and constructs for nanotechnology. The most relevant book is Volume III which is due in 2012 and focuses on reversing disease and the aging process.
The other volumes (basic capability and biocompatibility) are a pre-requirement, though.

Drexler-like, controllable, nanotechnology does not yet exist, but Drexler has demonstrated unrefuted physicochemical feasibility of his models, upon which Freitas builds his proposals.

Thnak you for this. It is quite clear that this will become a standard approach for repairing (or otherwise influencing) DNA. It won't take that long to happen either....

Yes.

The Nanomedicine series by Robert Freitas: http://www.nanomedicine.com/

They build directly on Drexler's work and constructs for nanotechnology. The most relevant book is Volume III which is due in 2012 and focuses on reversing disease and the aging process.
The other volumes (basic capability and biocompatibility) are a pre-requirement, though.

Drexler-like, controllable, nanotechnology does not yet exist, but Drexler has demonstrated unrefuted physicochemical feasibility of his models, upon which Freitas builds his proposals.

Thnak you for this. It is quite clear that this will become a standard approach for repairing (or otherwise influencing) DNA. It won't take that long to happen either....

Why do you suspect that won't take long? Sounds very difficult to pull off.

[/quote]

Why do you suspect that won't take long? Sounds very difficult to pull off.
[/quote]


It is very difficult, however based on the rate of current research in this, I would estimate that within 10 years we will be able to significantly influence human DNA using nanotechnology.
I remember just a few years ago there were hardly any papers on intervention nanonetchology mentioned in Medline. Today there are over a thousand. See for example basic research at:

http://www.ncbi.nlm....mp;ordinalpos=2

and

http://www.ncbi.nlm....mp;ordinalpos=1

Great, now there's a reason for optimism.

howcome every time I hear of a cool research people say "10-15 years"? :/

In 15 years time we'll look back at the primitive times in which we grew up and wonder what we ever did before we had (for a hefty monthly charge) nanoassemblers to repair our DNA from all the damage caused to it by the plefora of toxic chemicals in our air, water and food.
Edited by caston, 11 February 2010 - 03:11 PM.

howcome every time I hear of a cool research people say "10-15 years"? :/

Because by that time the researchers would have retired and there's no one left to point fingers at!

howcome every time I hear of a cool research people say "10-15 years"? :/

Because by that time the researchers would have retired and there's no one left to point fingers at!

Retire?! People who are interested in antiaging/longevity should never retire. It defeats the point.

You know, anti-shower research, initial assemblers for nanobots to remove sweat. A test monkey had nanobots under the armpits, but they don't wanted to make diamond structures, instead they crawled into the nose, caused sneezing all the time, and so on. What to do against sneezing is to use nanoparticles, at 1st here http://www.sciencebl...er_gene_therapy and then here http://web.mit.edu/n...icles-gene.html with biodegradable polymers, not only for armpits.

howcome every time I hear of a cool research people say "10-15 years"? :/

Because by that time the researchers would have retired and there's no one left to point fingers at!

Retire?! People who are interested in antiaging/longevity should never retire. It defeats the point.

lol It'd be ironic wouldn't it?

Retire?! People who are interested in antiaging/longevity should never retire. It defeats the point.

lol It'd be ironic wouldn't it?

Failures can be a matter of genetic causes. So it's better to prepare pointing at descendants deriving from monkeys like Mito and Tracker. They are the first animals that received the gift of life by a fertility method called spindle transfer, developed at the Oregon Health & Science University’s Oregon National Primate Research Center (ONPRC). When nanoparticles repair mutations on mitochondrial DNA from a monkey’s egg which nuclear DNA has been removed, nuclear DNA can be efficiently inserted into the repaired egg afterwards. Gene therapy is inevitably leading to healthier and longer living families of primates. Ideas proposed by usage of: OHSU Primate Center Scientists Develop Gene Therapy Method to Prevent Some Inherited Diseases http://www.ohsu.edu/...ent-disease.cfm Oregon Health & Science University, Aug 26 2009.
Edited by robomoon, 21 February 2010 - 12:48 PM.