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              Advocacy & Research for Unlimited Lifespans

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DNA Repair - common motif amongst longevity genes

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Posted 11 July 2004 - 06:40 AM

The functional result in the vast majority of longevity associated genes that have been discovered to play a role in model organisms spanning from yeast to mammals is to increase the rate of DNA repair, increase the rate of antioxidant production or decrease the rate of oxidant production. The common motif is that rate of DNA damage is reduced. The consequence is that the cell is less likely to become tumorigenic, apoptotic or senescent.

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