After reading this fascinating thread:
http://www.imminst.o...showtopic=18073
which involves using low doses of Naltrexon at night to artificially up-regulate opioid receptors in the brain (and thus naturally be more sensitive to opioids during the day in response).
I was wondering if the same concept (antagonist at night to create natural agonism during the day) could be used in relation to serotonin or dopamine.
So, brains of Imminst, I pose to you the following questions:
1) What serotonin receptor antagonists are there with minimal side effects and shortish halflife (6-8 hours or so max, or you wouldnt get any benefits)?
2) What dopamine receptor antagonists are there with minimal side effects and shortish halflife?
3) Would this work in the same way as using Naltrexon did to opioid receptors (eg force them to gain higher sensitivity to opioids)
4) What would be the likely effects on you the next day?
5) Any thought as to long term risks (or benefits?)
6) Any hormonal effects?
7) Anyone fancy being the guineapig?
Apologies if this is the mechanism by which something commonly used already acts and Im just being thick.
Edited by Lallante, 22 April 2010 - 02:59 PM.
