8 replies to this topic

[Full Flight]

Hi Everyone,

I've been taking Piracetam on and off, and every time I do (after an extended break) the effects are dramatic. I can do more work in two hours with Piracetam, in full flight mode, than I can in two days, and it's easier. I can simply focus like crazy when I'm on it. It's like my IQ jumped by 50 points.

Then after a day or two, the effects wane, and then I'm back to normal, no matter how much P I take. At this point, I have to take another break for a month or two before using it again.

I figured that the effects wore off because I ran out of fuel - that is, my choline levels were depleted. And it took my body two months to replenish these reserves. Problem is, I tried choline bitartrate for weeks while taking P, and it didn't make much of a difference (2-3g / day). Also threw in some alpha-GPC, but it only gave me crushing headaches.

What I want to know is,

1) Have any of you had a similar experience with P? That is, had MAJOR gains in mental power only to see it wane shortly after?
2) If so, what do you think could cause this sudden drop-off? What solutions did you try to implement? What were the results?

Any feedback that you could offer will be greatly appreciated. Thanks, everyone!

Best,

Michael

[risemystic]

you are right, by me the same satuation???!!!!!!!

what help me alot's ! i take 200mg 4 times a day it help very good!!1

Edited by risemystic, 03 August 2010 - 05:26 PM.

[FrequencyX]

you are right, by me the same satuation???!!!!!!!

what help me alot's ! i take 200mg 4 times a day it help very good!!1

Maybe its just me, but every one of your posts I read in Borat's voice.

[rvdvaart]

I meant to ask this question earlier but what is the latest time of day I should take Piracetam so it doesn't interfere with sleep?

[FrequencyX]

I meant to ask this question earlier but what is the latest time of day I should take Piracetam so it doesn't interfere with sleep?

Personally, I have found that I can usually take it about 4 hours before bedtime. Some don't have any issue at all.If I take it too close, I have trouble falling asleep.

[Duster]

I meant to ask this question earlier but what is the latest time of day I should take Piracetam so it doesn't interfere with sleep?

Personally, I have found that I can usually take it about 4 hours before bedtime. Some don't have any issue at all.If I take it too close, I have trouble falling asleep.

I have found the same thing myself, but I'm not sure why. I take piracetam 3 times a day, every 4 to 5 hours. But if piracetam has a half life of about the same, then the concentration of piracetam in my blood 5 hours after the last dose would be about .875 times the concentration immediately after the first dose. This doesn't seem like that much of a decrease, so why such a dramatic effect on sleep?

[chrono]

My current hypothesis is that brain acetylcholine levels have a lot to do with how much it affects sleep. I only seem to get insomnia when I supplement along with a choline source like alpha GPC. I recall some papers that suggest too much ACh can interfere with certain stages of sleep, but I'm not sure if it would also keep you awake. More research is needed.

[synapse]

Too much ACh does appear to have a marked effect on sleep and can accentuate dreaming. My sense is that there is a strong connection between ACh activity and REM sleep.

[chrono]

Too much ACh does appear to have a marked effect on sleep and can accentuate dreaming. My sense is that there is a strong connection between ACh activity and REM sleep.

Interesting point. Myself and several others have noticed that piracetam has a dramatic effect on dream frequency/remembrance and vividness, but if anything would have depleted ACh that late in the day. Perhaps it's a lingering effect of increased utilization, or (more likely) receptor upregulation?