I've never heard of adderall being implicated in blood thinning, and I'm unaware of any mechanisms that would affect healing for wisdom teeth.
well, the literature seems to have some mixed results:
http://www.ncbi.nlm....m00486-0205.pdf according to the article on sympathomimetic amines in this one, catecholamine release in general seems to
increase platelet aggregation, thus making the process of clotting faster. it should be noted, however that only levo-amphetamine and racemic amphetamine were tested. adderall contains no levo-amp and is only partially racemic amp, the remainder is dextro-amp.
http://journals.lww....egation.12.aspx this one, however, showed that racemic amphetamine (the one contained in adderall)
inhibited platelet aggregation. so it's a toss up with blood thinning.
however, iirc, i remember amphetamine inhibits "protein synthesis" and i remember this being big, unfortunate news on the M&M forums. the role of protein synthesis in tissue healing, however, i don't know.
agreed. the excessive amount of stress that amphetamines place on your body will divert resources away from the healing process.
while amphetamines taken in excess would certainly do so, the doses at which they are used therapeutically are a lot safer than one might expect. to put it in perspective, "street" amphetamine doses can range into amounts nearing whole entire grams, and is also stronger than typical medicinal amphetamine because if the
methyl group. adderall is amphetamine, and iirc, is only 1/6th as potent as
methamphetamine and the therapeutic index it has doesn't range much higher than 40mg, 1/25th of a gram.
I suppose so. In years of using adderall therapeutically, I never found it to give me dry mouth, and I think I'm pretty susceptible to that. It is a diuretic, and I have found it dehydrating if I don't up my water consumption, so I guess it may decrease saliva in that sense. But then, so would caffeine, probably.
actually, dehydration is not the reason behind the dry-mouth associated with amphetamines. the dry-mouth that comes from amphetamines is due to the anticholinergic properties that are typically associated with sympathomimetic amines. i'm not sure if caffeine has anticholinergic properties, but if it did, it wouldn't be nearly on the level that amphetamines do, as caffeine is a generalized PDE inhibitor. if you find that amphetamines don't give you dry-mouth, you might have a very active cholinergic system, or you may simply have a high anticholinergic tolerance.
Edited by Pike, 30 September 2010 - 06:43 PM.