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Adderall and Healing?


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13 replies to this topic

#1 martin30

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Posted 24 September 2010 - 07:01 PM


Does taking adderall slow down the process of healing. I just had wisdom teeth pulled out and obviously healing with this takes at least 2 weeks so Im wondering to not make it even longer.
Would taking adderall every day like I always do make the healing process slower? I remember at the dentist when he was done noticed that it was taking an unusual time for the blood to stop running before stitching it up. I didnt bother asking anything there. Everything was fine a couple minutes later.

Anyone know if adderall or amphetamines in general interfere with healing?

#2 Steve_86

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Posted 25 September 2010 - 08:13 AM

I would stop taking the Adderall if it gives you a dry mouth.

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#3 christopherforums

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Posted 26 September 2010 - 04:01 AM

amphetamines will put stress on your whole system...

the quickest way to heal wisdom teeth is probably sleep as much as possible, dont think about pain, meditate and think about healing

#4 chrono

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Posted 26 September 2010 - 01:41 PM

I've never heard of adderall being implicated in blood thinning, and I'm unaware of any mechanisms that would affect healing for wisdom teeth.

#5 Steve_86

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Posted 26 September 2010 - 01:55 PM

I've never heard of adderall being implicated in blood thinning, and I'm unaware of any mechanisms that would affect healing for wisdom teeth.


Amphetamines can reduce saliva production causing mouth dryness. This is bad for the teeth and gums so surely it would slow the healing for wisdom teeth.

Edited by Steve_86, 26 September 2010 - 02:24 PM.


#6 frederickson

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Posted 26 September 2010 - 01:57 PM

amphetamines will put stress on your whole system...

the quickest way to heal wisdom teeth is probably sleep as much as possible, dont think about pain, meditate and think about healing


agreed. the excessive amount of stress that amphetamines place on your body will divert resources away from the healing process.

#7 medievil

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Posted 26 September 2010 - 02:22 PM

amphetamines will put stress on your whole system...

the quickest way to heal wisdom teeth is probably sleep as much as possible, dont think about pain, meditate and think about healing


agreed. the excessive amount of stress that amphetamines place on your body will divert resources away from the healing process.

lol
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#8 chrono

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Posted 30 September 2010 - 10:19 AM

Amphetamines can reduce saliva production causing mouth dryness. This is bad for the teeth and gums so surely it would slow the healing for wisdom teeth.

I suppose so. In years of using adderall therapeutically, I never found it to give me dry mouth, and I think I'm pretty susceptible to that. It is a diuretic, and I have found it dehydrating if I don't up my water consumption, so I guess it may decrease saliva in that sense. But then, so would caffeine, probably.

#9 Pike

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Posted 30 September 2010 - 06:42 PM

I've never heard of adderall being implicated in blood thinning, and I'm unaware of any mechanisms that would affect healing for wisdom teeth.



well, the literature seems to have some mixed results:
http://www.ncbi.nlm....m00486-0205.pdf according to the article on sympathomimetic amines in this one, catecholamine release in general seems to increase platelet aggregation, thus making the process of clotting faster. it should be noted, however that only levo-amphetamine and racemic amphetamine were tested. adderall contains no levo-amp and is only partially racemic amp, the remainder is dextro-amp.
http://journals.lww....egation.12.aspx this one, however, showed that racemic amphetamine (the one contained in adderall) inhibited platelet aggregation. so it's a toss up with blood thinning.

however, iirc, i remember amphetamine inhibits "protein synthesis" and i remember this being big, unfortunate news on the M&M forums. the role of protein synthesis in tissue healing, however, i don't know.



agreed. the excessive amount of stress that amphetamines place on your body will divert resources away from the healing process.



while amphetamines taken in excess would certainly do so, the doses at which they are used therapeutically are a lot safer than one might expect. to put it in perspective, "street" amphetamine doses can range into amounts nearing whole entire grams, and is also stronger than typical medicinal amphetamine because if the methyl group. adderall is amphetamine, and iirc, is only 1/6th as potent as methamphetamine and the therapeutic index it has doesn't range much higher than 40mg, 1/25th of a gram.

I suppose so. In years of using adderall therapeutically, I never found it to give me dry mouth, and I think I'm pretty susceptible to that. It is a diuretic, and I have found it dehydrating if I don't up my water consumption, so I guess it may decrease saliva in that sense. But then, so would caffeine, probably.


actually, dehydration is not the reason behind the dry-mouth associated with amphetamines. the dry-mouth that comes from amphetamines is due to the anticholinergic properties that are typically associated with sympathomimetic amines. i'm not sure if caffeine has anticholinergic properties, but if it did, it wouldn't be nearly on the level that amphetamines do, as caffeine is a generalized PDE inhibitor. if you find that amphetamines don't give you dry-mouth, you might have a very active cholinergic system, or you may simply have a high anticholinergic tolerance.

Edited by Pike, 30 September 2010 - 06:43 PM.


#10 chrono

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Posted 01 October 2010 - 09:46 AM

adderall contains no levo-amp and is only partially racemic amp, the remainder is dextro-amp.

A racemate is a mixture of the d- and l-enantiomers. IIRC, adderall is about 75% d-amp and 25% l-amp. There's no 'hybrid molecule' that is the racemic portion, which I think is what you're assuming here.

And despite the possible anticholinergic mechanism you describe (which is interesting, but honestly I haven't done enough research on the physiological effects of amp to comment), dehydration can definitely cause drymouth. With some random googling, it seems like the incidence of dry mouth with adderall is only about 1/3, so I don't think I'm particularly strange in that regard.

Edited by chrono, 01 October 2010 - 10:03 AM.


#11 Pike

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Posted 01 October 2010 - 02:07 PM

adderall contains no levo-amp and is only partially racemic amp, the remainder is dextro-amp.

A racemate is a mixture of the d- and l-enantiomers. IIRC, adderall is about 75% d-amp and 25% l-amp. There's no 'hybrid molecule' that is the racemic portion, which I think is what you're assuming here

And despite the possible anticholinergic mechanism you describe (which is interesting, but honestly I haven't done enough research on the physiological effects of amp to comment), dehydration can definitely cause drymouth. With some random googling, it seems like the incidence of dry mouth with adderall is only about 1/3, so I don't think I'm particularly strange in that regard.


oi, you are right about racemites. double checked my notes, but yes. grave error on my part.

however, in terms of dry-mouth: dehydration could easily be one of the laundry list reasons behind dry-mouth, as you say. i simply wanted to specify that the dry-mouth that is associated with amphetamines is largely due to its anticholinergic properties. roughly anything dopaminergic is anticholinergic.

for those who have never used sympathomimetic dopaminergics, the dry-mouth associated with amphetamines is roughly the same as the "cottonmouth" of marijuana use, as THC is extremely anticholinergic, as well.

Edited by Pike, 01 October 2010 - 02:08 PM.


#12 J. Galt

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Posted 06 March 2011 - 06:06 AM

From a traditional Chinese medicine perspective, Adderal depletes jing energy reserves, the vital essence/life forced used for procreation and regeneration. So TCM would suggest that yes, adderall reduces healing time.

#13 medievil

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Posted 18 March 2011 - 12:20 AM

From a traditional Chinese medicine perspective, Adderal depletes jing energy reserves.

Can i buy jing from the supermarket to replace it again?
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#14 aLurker

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Posted 18 March 2011 - 02:09 PM

Yeah the hundreds of years old traditional Chinese medicine texts totally rip on Adderall. Furthermore, if you're born in the year of the dragon modafinil messes up your feng shui.

I'm off to the supermarket to buy a few gallons of mint flavored jing, l8r d00dz.




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