5 replies to this topic

[j03]

I'm taking 900 mg of Nature's Way Perika St. John's Wort. I want to add in 5 MG Lithium Orotate in the morning. I'm not noticing a perceptible mood boost with just St. John's Wort. I have both on hand and I've wanted to take both to repair stress induced brain damage and for neuroprotective and cognitive enhancing reasons... as well as a myraid of other benefits.
They should be safe from what I'm reading but I want to know what is the threshold I shouldn't pass? What's the max dose? Any indications, or anything I got to look out for? Anyone combine these two? Are they synergistic with there mood enhancing properties?
I also take curcumin so is this something I should cut out for risk of serotonin syndrome? I would assume so.

[Ark]

If your increasing your dosage do it slowly, you don't want to puke.

[NR2(x)]

I understand that lithiums benefits are derived only very close to the toxic concentration. As there is large variation in individual pharamkenetics it is essential that regular test are conducted of said concentrations, there are many drugs that can alter the excreation and hence induce toxicity, lithium toxicity results in failed kidney etc. Therefore the necessity for oversight of a medical Doctor is real.

[nito]

I tried mixing lithium orotate with either serofin, sc27 or perika. Can't say i felt any major boost, it was hard to tell to be honest. But i definately didn't feel worse. I added no more than 10 mg of lithium, most often only took 5 mg.

[Thorsten3]

I tried mixing lithium orotate with either serofin, sc27 or perika. Can't say i felt any major boost, it was hard to tell to be honest. But i definately didn't feel worse. I added no more than 10 mg of lithium, most often only took 5 mg.

Lithium decreases norepiniphrine according to wikipedia which is pretty important for mood. Although for those who have excessive levels it is probably pretty useful.

On its own Lithium lowered the amount of enjoyment, pleasure and excitement I was able to gain from day to day life, but was relaxing and stabalizing. It must be great for those who have chronic stress and a overactive mind. I only tried 10mg per day so the effects might vary at different dosage levels.

SJW apparantly interacts with norepiniphrine as well so there could possibly be a clash of interests in this respect.

I however combined the two with no problems. SJW, for me just overpowered the Lithium but there were definitely no contradictions.

Edited by Thorsten, 28 November 2010 - 12:26 PM.

[longevitynow]

Lithium orotate is typically taken at doses far, far below pharmaceutical lithium. It does appear to be good for the brain in these small doses. Typical dose of lithium orotate is 5 mgs 2x/day. That's probably a good dose for most people, but you could safely double that (particularly if you might be somewhere on the bipolar spectrum). I would not expect you will find it to be a cognitive sharpener. It is a mild calming agent. For depression, it is more for someone who has a more anxious depression than a lethargic depression, but in those low doses you are very unlikely to overly sedate yourself with it. And it may well prove to be good for lethargic depression in the log run in that it is neuroprotective/ neuroregenerative effects. But those are probably very slow and arguably not very noticeable effects. I don't see any contraindications combining SJW and lithium orotate.

Jonathan Wright wrote some excellent articles on nutritional lithium:

http://www.tahomacli.../lithium1.shtml