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Very fat doses of spirulina and chlorella


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#1 caruga

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Posted 12 February 2011 - 07:37 PM


I'm a chronic fatigue syndrome sufferer. I just took 10 grams of spirulina and 10 grams of chlorella, blended in a large amount of water. It was a bit like an adrenaline rush, but different (norepinephrine?). Regardless it's raised by energy through the roof, it's absolutely raging. I just did a hundred knee-highs to work some of it off (it wasn't premeditated, just spontaneous, like I can't contain the torrential energy), and I feel absolutely no signs of flagging or that somewhere something is being overtaxed. To give you another idea, I have to restrain myself when writing this to not write liiiiiiiike thIIIIIS, the current state I'm in seems to create the outward behaviour of giddiness, even though I don't feel emotionally giddy, just stupidly energised. Could it be the mineral content? The chlorophyll? What's going on?
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#2 VampIyer

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Posted 14 February 2011 - 01:29 AM

It may be the high quantity of phenylalanine ---> tyrosine, contained in Spirulina.

Spirulina contains B12-analogues which will bind to the receptor, and are thus capable of producing falsely high levels on a B12 blood test. It'd be a good idea to supplement real methyl-b12 if you take large quantities of spirulina.

Other than that, spirulina seems to help me endure physical stress (workouts) slightly better. I'm not sure that I notice anything from chlorella... note that these two supplements are not plants, but algae. I've read about certain risks of contamination WRT spirulina, but I believe some manufacturers test for this.

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#3 caruga

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Posted 15 February 2011 - 03:08 AM

Maybe, but supplementing tyrosine directly doesn't give me these benefits. Although I've taken the same dosage of green powders a couple of times since and the effects weren't nearly as pronounced (story of my life).

#4 unregistered_user

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Posted 22 March 2012 - 09:52 PM

Caruga, can you give us an update?

What brands of spirulina and chlorella were you taking specifically and are you currently taking them? I too have CFS and am reading very positive things about this combination. Are your products bulk or in capsules?

#5 caruga

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Posted 23 March 2012 - 01:03 AM

Hi,
It was a one off, I could never reproduce the effect again. I can't remember the brand, although I do think brand can make a difference (I blew £50 on a kilo of chlorella off of ebay since then, and it didn't smell or taste nearly as pungent). My suspicion is that it was some sort of detoxification occuring, though why it only happened that one time is a mystery. I've been through a lot since this incident. I've had far more extreme results with other substances since--only to find myself here and now stuck in a rut once again. See this link where I try (and fail) to find some answers, if you're interested (there's also evidence on this site of that period I went through that the link talks about).

EDIT: best just read the link, ignore the following crap at least until after reading it.

I may ramble on here (I know some (most?) cfs sufferers have harder times with text wall than I do... consider it a forewarning...) All I know is that there is a high likelyhood of a mismash of diminished methionine synthase activity (taking colostrum gives me a boost, and the IGF is known to stimulate methionine synthase), perhaps brought on my mercury toxicity, and low glutathione which may also be due to that, or due to folate and b12 deficiencies. It's hard to know which started first. Low glutathione could have caused mercury to accumulate that would pass through a normal person harmlessly, or the low glutathione could have started only after a shock dose of mercury (perhaps from a vaccine, though I can't access my medical records to find out if I had one around the time I came down with CFS--it would explain a lot if I had).

Back in the end of May due to the breakthroughs I talk abotu in the link I felt like an absolute god. I was hypomaniacal and megolomaniacal, but it wasn't all delusion... I had very measurable cognitive improvements and total lift of brain fog--it was like becoming sentient. I think I just went mad with power because I felt powerful--super super super healthy and normal really and it was just the contrast that made it feel god-like.

At the best point I was ready to pronounce my fatigue almost totally gone.

Right now I'm completely lost. The fatigue has come back and it feels like none of the dramatic leaps forward last year ever happened. I wonder if the whole theory of moving mercury into the brain is true. That oft-repeated idea originates from Cutler, the 'grandfather' of detox wisdom. People utter the things he said like they're saying it for the first time or it was their own idea, making it look like a commonly accepted notion, but it all originates from him. The thing is I haven't ever seen him cite his sources, so I don't know how he knows what he's saying anymore than the people who quote him know what they're saying. But maybe he knows what he's talking about. It's on my to-do list to try his protocol sometime... if I can find it in me to sacrifice this damn amalgam filling first that I never asked for! (stupid dentist, need to change him).

Another possibility is that I caused serious upsets in my bodily chemistry by what I was doing to it. NAC depletes all minerals over time. I may have induced a selenium deficiency for example.

I still get the "detox episodes" I mention in that link--but they went frmo lasting whole days, to lasting half a day with many days inbetween episodes, to lasting an hour and a week between episodes, to now where it lasts about 20 minutes max. Intensity is also far less. What I do to instigate it is also extremely random. It would be nice to think that that means there's just less to detox, but deep down I don't feel that that's the case. I'm nothing like the walking on cloud 9 I had last year. I can taste the memory of it, but I'm a complete joke compared to him.

One thing i'm reintroducing again to my regimin is ashwagandha. Read an article about it raising glutathione (or some derivative) in the spine. Which is where I get shudders from. What do you know, according to my logs I was taking that on the week leading up to my breakthrough... and dropped it afterward (out of fear of it containing heavy metals!). But everything else was important to... it's like some cosmic event where stars align only every thousand years... everything I was taking at that time just happened to come into perfect alignment and induce this absolutely torrential physiological process that made me feel super healthy and fixed. I think I was just super super lucky to have it happen. Now I just need to figure out what the hell I did. Everything I initially attributed it to--NAC, potassium and sodium chloride, and sodium bicarbonate, are no less significant. But I think it's a lot more than that and what I never wrote of to begin with was everything else I was taking... I think it ALL mattered. I think my subconscious guided me to certain substances based on the masses of literature I'd read and the reasons for picking up the various things I did.

Sorry, that's a really rambling post, but it's hard to be coherent with the fatigue. If I had to give you any advice thoguh i'd say take no shortcuts, and never stop learning how this stuff all works. I'm beginning to build up a picture in my head, but i'm getting no help with it, it's all self taught. Eventually I hope to work my way out of this maze...

Edited by caruga, 23 March 2012 - 01:08 AM.

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#6 unregistered_user

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Posted 26 March 2012 - 03:46 AM

Great post, thank you! I hope you find that elusive combination of substances and appreciate you taking the time to respond.

#7 fruitlover

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Posted 31 July 2012 - 08:24 AM

Whoah! Seems like you just did an expirement and did not ask your doctor when you took 10 grams of spirulina and 10 grams of chlorella. Are the actual amount prescribed by your doctor or you just tried it yourself? If you've just done it yourself, please refrain from doing so. As this may affect your entire health. Good thing these are just supplements. Please make sure to ask your doctor first if it's good on you and won't have any side effects then also ask for the exact prescriptions. Hope you are now ok.
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#8 MercuryAX

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Posted 01 October 2013 - 11:25 PM

Spirulina contains Phycocyanobilin, which inhibits NADPH oxidase. Perhaps that could have something to do with it?

#9 Darryl

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Posted 02 October 2013 - 06:36 AM

10 grams of spirulina is not a particularly large amount. If you want to learn all about phycocyanobilin, Mark McCarty at Catalytic Longevity has written a number of "Medline synopses" that touch on some potential benefits:

Phycocyanobilin from spirulina - the master antioxidant
Full-spectrum antioxidant therapy: minimizing the contribution of oxidative stress to disease and aging
Practical strategies for preserving good cognitive function into old age
Clinical potential of phycocyanobilin for induction of T regulatory cells in the management of inflammatory disorders
Spirulina and its chromophore phycocyanobilin have potential for alleviation of asthma
Targeting adipocytes in metabolic syndrome – spirulina and salsalate may complement the benefits of PPARgamma agonists
Phycocyanobilin and dietary nitrate may exert natriuretic effects that suppress production of marinobufagenin
A potential role for spirulina in the prevention and management of preeclampsia

...and so forth.

Of course, any Nrf2 inducer will upregulate heme oxygenase-1 and production of bilirubin, the body's own NADPH oxidase inhibitor, so its not obvious that spirulina is the best way to press this button.
XP to caruga, yes ashwangandha is also an Nrf2 inducer - which probably accounts for that reported increase in spinal glutathione. This isn't a particularly special quality, lots and lots of hormetins work via this mechanism.

And there remain concerns with microcystin and neurotoxin contamination of spirulina:

Jiang, Y., et al. "Detection of the hepatotoxic microcystins in 36 kinds of cyanobacteria Spirulina food products in China." Food Additives and Contaminants 25.7 (2008): 885-894.
Mazokopakis, Elias E., et al. "Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis)." Phytomedicine 15.6 (2008): 525-527.
Rellán, Sandra, et al. "First detection of anatoxin-a in human and animal dietary supplements containing cyanobacteria." Food and Chemical Toxicology 47.9 (2009): 2189-2195.
Moulis, Guillaume, et al. "Severe neonatal hypercalcemia related to maternal exposure to nutritional supplement containing Spirulina." European journal of clinical pharmacology 68.2 (2012): 221-222.

The problem is not so much with spirulina (which, when pure, has generally regarded as safe status) but with other species of blue-green algae which can find their way into the same ponds. Given microcystin test strips used to test drinking and recreational water cost $15, its really unconscionable that spirulina producers don't test every batch.

Edited by Darryl, 02 October 2013 - 06:55 AM.

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#10 hallucinogen

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Posted 27 January 2014 - 11:22 AM

I can tell you one thing for certain, when I blend these very high quality Organic Spirulina tablets with pure water, just 3 tablets, the resulting concoction resembles a swamp sewage water exactly in its taste and fragrance, maybe it did get contaminated, but I'm not exactly sure where to get legit testing strips and what concentration to make the solution to, to test it, because the strips are usually meant for drinking water and operate within a limited range

Edited by hallucinogen, 27 January 2014 - 11:23 AM.





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