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Frustration over Psoriasis / Dermatitis


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#1 chinaski

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Posted 20 May 2011 - 12:05 PM


Hello everyone, I just joined the forum ;)

In short, during the last months my case of psoriasis/dermatitis that was only slightly present on my nose and forehead got worse and extended to my scalp,
ears, underarms, elbows, chest and groin area... all in a matter of months. My lifestyle was very unhealthy at the time, with poor nutrition, high level
of stress, alcohol, coffee and cigarettes consumption.

Just for the record, I have been to many doctors and dermatologists, and I have been never properly diagnosed with a condition, but they all said
I either have psoriasis or dermatitis. Well, I've been told that my grandmother had psoriasis, so I guess I have that too.

At the moment, I'm not using anything, as I've used steroids in the past and it didn't help much, but I did some lifestyle changes that may help on the long run:
I stopped smoking, drinking alcohol and coffee, eating grains, using any kind of hair products, using shampoo and conditioner.
So far the only improvement that I see is that the condition is not getting worse, and that the flakes in my scalp are getting bigger (I don't know if this
is good or not..)

What I'm mostly concerned with at the moment is the groin area. I really need to deal with this as it's destroying my social/sexual life, and I've been already depressed
about the condition in general in the last months.
I already made a commitment that I will find a solution no matter what, but I need some help, since I don't really know where to do about it..

#2 Sciolaro

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Posted 20 May 2011 - 01:22 PM

There might be helpful findings in this article: http://www.reuters.c...E67G4EN20100817

If I remember right, Michael Hollick had unprecedented success treating psoriasis with a topical Vitamin D solution.

Good luck to you.

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#3 niner

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Posted 20 May 2011 - 01:28 PM

Hi chinaski, welcome to longecity! Skin conditions like this suck. I don't blame you for being distressed by this; you aren't alone. There are lots of treatments for psoriasis. None of them are perfect, but you can certainly get some relief. You need to make an appointment with a dermatologist and get going with a treatment regimen. The changes you've made in your lifestyle are positive steps. Keep them up. (Smoking and alcohol are known psoriasis triggers) Here is a pretty good list of lifestyle tips. It wouldn't be a bad idea to take 1-3 grams/day of fish oil, if you aren't already. Good luck with finding some relief.

#4 GhostBuster

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Posted 21 May 2011 - 03:24 PM

Lately I have searched information about fungal infections and cancer and I bumped into theory that says that psoriasis also is caused by fungus. I havent investigated the subject matter, but I find the explanation very appealing. You might want to google and check if you can find something useful. Here is how Dr Simoncini who is the advocate of fungal theory would treat psoriasis:

http://www.curenatur...-psoriasis.html

Edited by GhostBuster, 21 May 2011 - 03:27 PM.

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#5 charlototo

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Posted 30 May 2011 - 02:50 AM

Lately I have searched information about fungal infections and cancer and I bumped into theory that says that psoriasis also is caused by fungus. I havent investigated the subject matter, but I find the explanation very appealing. You might want to google and check if you can find something useful. Here is how Dr Simoncini who is the advocate of fungal theory would treat psoriasis:

http://www.curenatur...-psoriasis.html



Look like interresting..do you have any information about that ?

#6 niner

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Posted 30 May 2011 - 03:10 AM

Lately I have searched information about fungal infections and cancer and I bumped into theory that says that psoriasis also is caused by fungus. I havent investigated the subject matter, but I find the explanation very appealing. You might want to google and check if you can find something useful. Here is how Dr Simoncini who is the advocate of fungal theory would treat psoriasis:

http://www.curenatur...-psoriasis.html

Dr. Simoncini sounds like a nut. He thinks that psoriasis AND cancer are caused by fungi.

#7 freddy

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Posted 30 May 2011 - 08:02 AM

Well I was just passing through the forums, but when i read your post I thought I better share what worked for me because i had EXACTLY the same situation and i felt pretty down about it until i finally solved it.

I had seborrhea/psoriasis in quite a few places but to be honest i didn't give a f^&* about that compared to having it on a) my face and b) the family jewels. Totally confidence shattering, and having to deal with 'what happened to your face' daily for months (it looked like a handprint on my face and everyone i met thought id been punched) was annoying.

I tried many many different types of creams until i finally found the one that worked for me.

For me what finally worked was Tacrolimus 0.1% ointment. It's apparently what you should use on sensitive skin like your face and genitals.

Was pretty expensive here in Australia, about $100 but i would mortgage anything i had to fix it, so well worth it.

It cleared it up after about a 6weeks, but it was a case of one step forward 7 steps back, if i missed putting it on for even one day it would set me back a week and come straight back. So set a phone alarm which is what i did to never forget.

It worked for me, so hopefully it works for you too, find a doctor and demand to try it, if you havn't tried it already.

in summary
1) get prescription for tacrolimus 0.1% ointment
2) use twice daily for at least 3months before saying it doesn't work.
3) Keep your head up high regardless (i got my current GF with it at the time and surprisingly she didn't care at all)

Good luck

Freddy


ps. there are many other options available to you to so dont give up!!!!
pps. Don't spend too much time reading about possible diet/ lifestyle changes or causes on the internet it will only confuse you more. There are too many conflicting theories, i know i searched long and hard and there were people advocating all kinds of lifestyle changes due to the fact that for many it clears up by itself so they make false linkages.
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#8 GhostBuster

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Posted 01 June 2011 - 08:13 PM

Lately I have searched information about fungal infections and cancer and I bumped into theory that says that psoriasis also is caused by fungus. I havent investigated the subject matter, but I find the explanation very appealing. You might want to google and check if you can find something useful. Here is how Dr Simoncini who is the advocate of fungal theory would treat psoriasis:

http://www.curenatur...-psoriasis.html



Look like interresting..do you have any information about that ?


Here's some general information:

http://www.curenaturalicancro.com/

Interestingly previously mentioned tacrolimus is antifungal:

Antifungal Activities of Tacrolimus and Azole Agents against the Eleven Currently Accepted Malassezia Species
http://jcm.asm.org/c.../full/43/6/2824

yeasts have a role to play in the development of the various skin deseases:

Although lipophilic yeasts, Malassezia spp., colonize the skin surface of healthy individuals, they may also cause seborrheic dermatitis (SD), pityriasis (tinea) versicolor, and Malassezia folliculitis and may exacerbate atopic dermatitis (AD) (1). AD is a common chronic inflammatory skin disease. The standard treatment of AD is topical corticosteroids and topical immunomodulating agents, although some patients do not respond to these treatments. Cutaneous microorganisms are considered an exacerbating factor. Although large numbers of lipophilic Malassezia species organisms colonize the skin surfaces of both AD patients and healthy subjects, anti-Malassezia-specific immunoglobulin E antibody is detected only in AD patient sera (14, 16, 32). This is probably owing to the disrupted barrier function of the skin surface and the effects of scratching on sensitization to the organisms (30). The application of topical antifungal agents to AD patients decreases Malassezia colonization and the severity of eczematous lesions (2), suggesting that Malassezia species play a role in atopic dermatitis. In addition, several candidate Malassezia antigens have been implicated in the pathogenesis of AD (15, 19, 20, 23, 34).

I did an experiment and treated 2 of my moles (bigger ones) with 4,4% iodine tincture. I followed the instructions that Simoncini gives for treating the skin cancer thinking that if the treatment cures skin cancer then why not also moles. Within two weeks both moles disappeared. Now there are two red spots (hopefully not scars) instead.

#9 Logan

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Posted 07 June 2011 - 05:12 PM

Glycerin may be helpful


Abnormal aquaporin-3 protein expression in hyperproliferative skin disorders.
Voss KE, Bollag RJ, Fussell N, By C, Sheehan DJ, Bollag WB.
Source
Institute of Molecular Medicine and Genetics, Georgia Health Sciences University (formerly Medical College of Georgia), 1120 15th Street, Augusta, GA, 30912, USA.


Abstract
Non-melanoma skin cancers (NMSCs) and psoriasis represent common hyperproliferative skin disorders, with approximately one million new NMSC diagnoses each year in the United States alone and a psoriasis prevalence of about 2% worldwide. We recently demonstrated that the glycerol channel, aquaporin-3 (AQP3) and the enzyme phospholipase D2 (PLD2) interact functionally in epidermal keratinocytes of the skin to inhibit their proliferation. However, others have suggested that AQP3 is pro-proliferative in keratinocytes and is upregulated in the NMSC, squamous cell carcinoma (SCC). To evaluate the AQP3/PLD2 signaling module in skin diseases, we determined their levels in SCC, basal cell carcinoma (BCC) and psoriasis as compared to normal epidermis. Skin biopsies with the appropriate diagnoses (10 normal, 5 SCC, 13 BCC and 10 plaque psoriasis samples) were obtained from the pathology archives and examined by immunohistochemistry using antibodies recognizing AQP3 and PLD2. In normal epidermis AQP3, an integral membrane protein, was localized mainly to the plasma membrane and PLD2 to the cell periphery, particularly in suprabasal layers. In BCC, AQP3 and PLD2 levels were reduced as compared to the normal-appearing overlying epidermis. In SCC, AQP3 staining was "patchy," with areas of reduced AQP3 immunoreactivity exhibiting positivity for Ki67, a marker of proliferation. PLD2 staining was unchanged in SCC. In psoriasis, AQP3 staining was usually observed in the cytoplasm rather than in the membrane. Also, in the majority of psoriatic samples, PLD2 showed weak immunoreactivity or aberrant localization. These results suggest that abnormalities in the AQP3/PLD2 signaling module correlate with hyperproliferation in psoriasis and the NMSCs.

PMID:21400035[PubMed - as supplied by publisher]

#10 jughead

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Posted 20 June 2011 - 10:06 PM

If it is the topical Vitamin D, sunbathers and UV therapy patients should try not showering for 24 hours post treatment. There has been a study showing most of the vitamin d sits on the skin and takes 24 hours to absorb fully.

#11 Skötkonung

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Posted 20 June 2011 - 11:39 PM

I'm curious if you have tried removing dairy from your diet?

#12 madanthony

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Posted 13 July 2011 - 09:34 PM

Hello everyone, I just joined the forum ;)

In short, during the last months my case of psoriasis/dermatitis that was only slightly present on my nose and forehead got worse and extended to my scalp,
ears, underarms, elbows, chest and groin area... all in a matter of months. My lifestyle was very unhealthy at the time, with poor nutrition, high level
of stress, alcohol, coffee and cigarettes consumption.

Just for the record, I have been to many doctors and dermatologists, and I have been never properly diagnosed with a condition, but they all said
I either have psoriasis or dermatitis. Well, I've been told that my grandmother had psoriasis, so I guess I have that too.

At the moment, I'm not using anything, as I've used steroids in the past and it didn't help much, but I did some lifestyle changes that may help on the long run:
I stopped smoking, drinking alcohol and coffee, eating grains, using any kind of hair products, using shampoo and conditioner.
So far the only improvement that I see is that the condition is not getting worse, and that the flakes in my scalp are getting bigger (I don't know if this
is good or not..)

What I'm mostly concerned with at the moment is the groin area. I really need to deal with this as it's destroying my social/sexual life, and I've been already depressed
about the condition in general in the last months.
I already made a commitment that I will find a solution no matter what, but I need some help, since I don't really know where to do about it..

I'm sorry I am not going to reproduce the study for you that I did for someone I know in person - you will have to do that yourself - but I found studies that said that psoriasis can be cured with high dose omega-3 fish oil. I first read about this via Omega RX Zone by Dr. Barry Sears (not regarding psoriasis) and he said it would relieve my allergic rhinitis at 9g/day. (To do 9g/day you need to get fish oil that is pesticide and heavy metal free and w/o strange algae fat in it which causes upset stomach). It gets priority of the fat breakdown enzymes which then get used up and cannot break down the afats to inflammatory cytokines. I knew this so I researched omega-3 for psoriasis and I found that according to one study a 4.5 g/day dose would start to reduce psoriasis in 2 weeks (they did not test the higher dose -- 9g is immediateley effective for rhinitis). But furthermore, the study said over time it would cure the actual damaged underlying cells permanently so there would be no more flare ups. Now I think if you get psoriasis and go long enough w/o omega-3 again some NEW cells might develop with the problem. But maybe you don't need so high a dose once you get it under control. Look into it at www.google.com/scholar. Good luck. If you are short on omega-3 and you take a drug instead of fixing your shortage I am sure you will find other problems cropping up from the untreated deficiency. This is a major reason I think drugs are a poor choice.
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#13 Luminosity

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Posted 15 July 2011 - 06:54 AM

My lifestyle was very unhealthy at the time, with poor nutrition, high level
of stress, alcohol, coffee and cigarettes consumption.

THAT'S LIKELY MUCH OF THE CAUSE

At the moment, I'm not using anything, as I've used steroids in the past and it didn't help much, but I did some lifestyle changes that may help on the long run:

I BELIEVE THAT

I stopped smoking, drinking alcohol and coffee, eating grains,

VERY GOOD AND NOT EASY TO DO. KUDOS

I already made a commitment that I will find a solution no matter what.


RIGHT ON. I WOULD LIKE TO COMMENT MORE BUT I DON'T HAVE ENOUGH TIME RIGHT NOW. TRY AVOIDING SWEETS, AND COLD FOODS OR DRINKS. IN CHINESE MEDICINE THESE AGGRAVATE SKIN PROBLEMS, WHICH THEY CONSIDER TO BE YIN AS ARE THOSE FOODS. IF YOU EAT FRUIT, LET IT COME TO ROOM TEMPERATURE. DRINK A HOT DRINK AT BREAKFAST AND EAT A HOT BREAKFAST. AVOID TOO MANY ACIDIC FOODS OR DRINKS AS THEY WILL MAKE IT WORSE. I WOULD SEEK OUT AN ACUPUNCTURIST/PRACTIONER OF ORIENTAL MEDICINE. IF YOU GET A GOOD ONE, THEY WILL REALLY HELP.
I WILL COME BACK AND WRITE MORE STUFF LATER. GOOD LUCK.
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#14 SATANICAT

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Posted 20 July 2011 - 05:36 AM

I have a patch of irritated redness on the side of my face that the dermatologist hasn't diagnosed yet, and I have recently started taking l-lysine, high dose fish oil, and grapeseed and I'd like the say it may be reducing redness and healing the condition. But our conditions may not be similar, if I had to guess I'd say I have rosacea but there's a possibility that it's psoriasis too because it runs in my family. But I'd definitely suggest l-lysine most amongst the supplements mentioned. I take about 3 grams/day.

#15 Luminosity

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Posted 28 July 2011 - 03:42 AM

chinaski,

I could look up some non-toxic fragrance free hypoallergenic hair products for you if you like. If there's anything else I can contribute, I will. Just let me know by writing on this thread of sending me a message. I only come to this site now and then but I will respond eventually. Good luck.




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