It's surprising how powerful and well studied the safe plant alkaloid tetrandrine is for cancer ranging from 1 to 80 uM: in vivo brain (glioma), in vivo Ehrlich ascites carcinoma (EAC), breast, lung, neuroblastoma, esophageal, cervical, Burkitt’s lymphoma, hepatoma, and several leukemias.
150 mg/kg oral in rats for brain cancer (gliomas) in rats, with very low toxicity
http://onlinelibrary...2/ijc.24208/pdf
Applied daily for 28 days, 100% survival in both groups after 100% of controls were dead at day 60. 70% survival to 120 days for treatment that began immediately, and 50% survival when waiting 5 days after glioma innoculation.
$132 for 250 mg, so i would inject it.
http://www.enzolifes...60/tetrandrine/
in vitro 3 different liver cancers, IC50: 4 to 30 uM (2.5 to 20 ug/mL)
http://ntur.lib.ntu....176791/1/09.pdf
in vitro 2 breast cancers, IC50 15 to 24 uM, 1 to 2 uM to inhibit proliferation
http://www.mdpi.com/...94/3/2/2274/pdf
2002 overview in cervical, breast, leukemia, Ehrlich ascites carcinoma (EAC), and esophageal
http://www.chinaphar...083/23/1102.pdf
in inflammatory pulmonary diseases:
http://www.chinaphar...083/23/1107.pdf
comparison to many BBIQ alkaloids, Isotetrandrine was even better (toxicity for the later: oral LD50 in mouse 6.4 g/kg)
http://www.ncbi.nlm....c00367-0102.pdf
