1 votes
Posted 21 December 2011 - 04:26 AM
Posted 23 December 2011 - 01:59 AM
Posted 23 December 2011 - 10:24 PM
Posted 31 December 2011 - 10:57 PM
Posted 01 January 2012 - 06:34 AM
Posted 01 January 2012 - 11:54 AM
I kept taking the sarcosine on a daily basis and the headaches went away. I got headaches when I began risperidone too, my body was probably just adjusting.
I've been taking the sarcosine and the NAC for about a week now. So far I haven't really felt any noticeable effects. Maybe less anxiety and overall worry - but I have been trying to be more relaxed so the sources of the calmness are unclear. I haven't been taking a fixed dose of sarcosine until today though since I didn't have a scale (got it in the mail yesterday). Should I feel effects from sarcosine right away? In the studies, effects were seen within 6 weeks and at 2 grams per day so I'm going to take that amount for the next few weeks.
Posted 05 January 2012 - 01:49 AM
Safety of long-term high-dose minocycline in the treatment of acne
Summary
Minocycline is widely used as a second-line antimicrobial for acne vulgaris. Some patients require doses of up to 200 mg daily to control their acne. To assess the long-term safety of minocycline when used at higher doses, 700 patients treated with minocycline at doses of 100 mg daily, 100/200 mg on alternate days and 200mg daily, were recruited. The mean duration of treatment was 10·5 months. Side-effects were monitored and full blood count, blood urea, electrolytes and liver function tests were carried out on 200 of the 700 patients. Side-effects were recorded in 13·6%, and included vestibular disturbance, Candida infection, gastrointestinal disturbance, cutaneous symptoms (pigmentation, pruritus, photosensitive rash and urticaria) and benign intracranial hypertension. Pigmentation was the only side-effect found to be significantly increased in patients taking higher doses of minocycline, as compared with lower doses (P < 0·01). All patients with pigmentation had taken a total cumulative dose of over 70g. No significant abnormalities were found in any of the haematological and biochemical profiles. We conclude that minocycline, at doses of up to 200 mg/day, is safe, long-term, for acne, when such doses are clinically necessary.
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas.
Torrey EF, Davis JM.
Source
The Stanley Medical Research Institute.
Abstract
The pharmacologic treatment of schizophrenia and bipolar disorder leaves much to be desired. Repurposed drugs, which are approved for other medical conditions, represent an underutilized therapeutic resource for patients who have not responded to other drugs. Using experience gained from a decade of repurposed drug studies by the Stanley Medical Research Institute and search of the literature, we have identified nine such drugs for which there is some evidence of efficacy for schizophrenia and/or bipolar disorder. These include: aspirin; celecoxib; estrogen/raloxifene; folate; minocycline; mirtazapine; omega-3 fatty acids; pramipexole; and, pregnenolone. The evidence of efficacy is reviewed for each drug. Because there is little or no financial incentive for pharmaceutical companies to promote such drugs, there is a paucity of definitive trials, and these drugs are less widely known than they deserve to be. Biomarker studies should also be carried out to identify subgroups of patients who do respond to these drugs.
I kept taking the sarcosine on a daily basis and the headaches went away. I got headaches when I began risperidone too, my body was probably just adjusting.
I've been taking the sarcosine and the NAC for about a week now. So far I haven't really felt any noticeable effects. Maybe less anxiety and overall worry - but I have been trying to be more relaxed so the sources of the calmness are unclear. I haven't been taking a fixed dose of sarcosine until today though since I didn't have a scale (got it in the mail yesterday). Should I feel effects from sarcosine right away? In the studies, effects were seen within 6 weeks and at 2 grams per day so I'm going to take that amount for the next few weeks.
The source of your calmness may be because of Sarcosine... I recommend taking Sarcosine together with D-aspartic acid, this combination is more potent.
Posted 17 April 2013 - 09:54 AM
But in general schizophrenia medications tend to be the opposite of smart drugs.
Posted 17 April 2013 - 04:17 PM
Per definition these are positive symptoms, not cognitive symptoms.just go to your local psych ward, they come in disorganized and nonsensical and come out medicated and making sense of things and looking after themselves better.
Posted 18 April 2013 - 09:01 AM
But in general schizophrenia medications tend to be the opposite of smart drugs.
This isnt true, anti psychotics boost cognition and functioning in skitzophrenia and related psychosis', just go to your local psych ward, they come in disorganized and nonsensical and come out medicated and making sense of things and looking after themselves better.
Edited by Application, 18 April 2013 - 09:05 AM.
Posted 30 April 2013 - 08:50 PM
APs schrink the brain,But in general schizophrenia medications tend to be the opposite of smart drugs.
This isnt true, anti psychotics boost cognition and functioning in skitzophrenia and related psychosis', just go to your local psych ward, they come in disorganized and nonsensical and come out medicated and making sense of things and looking after themselves better.
True, that is an accurate observation watching folks going through and coming out of acute exacerbation. But over time, cognitive decline is well documented. There is even some research pointing to lower lifetime recovery rates when medicine is used chronically. What you see is relief from terror, disorganizing anxiety, and florid psychotic symptoms. This improves functioning in all realms when compared to the decompensation leading to a locked ward.
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