←  Brain Health

LONGECITY


The above is an ad! Advertisements help to support the work of this non-profit organisation. To go ad-free join as a Member.
»

A good article about methylation, depressi...

MrHappy's Photo MrHappy 05 Jan 2012

http://www.enzymestu...methylation.htm

A well-written article, explaining various pathways, dietary requirements and differences in effectiveness of some drugs and supplements in different groups of people - eg. Why some people have bad reactions to SSRIs, why SAMe is effective for some and not others and a lot more.

Worth reading, especially if you are new to supplements.
Quote

LeonardElijah's Photo LeonardElijah 15 Jan 2012

Thanks.

They need to stop talking about folic acid and start talking about methylfolate.

I respond to methylfolate.

Required to produce SAMe:

TMG
B6 in the form of P5P
Methylfolate
MethylB12

I can't speak to the minerals such as zinc because I never responded to those when messing around with methylation.

I qualify as an "overmethylator" when I add in the TMG. Sometimes I'm not stressed ENOUGH. The conversion is Choline (4 methyl groups) -> TMG (three methyl groups) -> DMG (two methyl groups). By dropping TMG, you are relying on choline. It's not like this is the biggest issue ever, but sometimes I want a little more stress incentive to get my stuff done.
Edited by LeonardElijah, 15 January 2012 - 07:13 PM.
Quote

Thorsten3's Photo Thorsten3 15 Jan 2012

http://www.enzymestu...methylation.htm

A well-written article, explaining various pathways, dietary requirements and differences in effectiveness of some drugs and supplements in different groups of people - eg. Why some people have bad reactions to SSRIs, why SAMe is effective for some and not others and a lot more.

Worth reading, especially if you are new to supplements.


Good read thanks
Quote

WillHen's Photo WillHen 27 May 2014

Thank you MrHappy...great information
Quote