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Brunotto's psoriasis regimen

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#31 brunotto

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Posted 02 February 2013 - 07:56 PM

hey brunotto, have you ever heard of chaga? i can't vouch for it with a personal testimonial, but i've read that it can be very effective for psoriasis (and overal health). probably worth looking in to.


No... but found this.
Research has supported the folk evidence that Chaga possesses potent immune supporting actions. Chaga is a rich source of β-glucans, especially 1-3-β-glucans, polysaccharides that are quintessential nutrients for the immune system. These polysaccharides have strong anti-inflammatory and immune balancing properties, enhancing the body’s ability to produce natural killer (NK) cells to battle infections. These polysaccharides are considered to be the primary active constituents of Chaga, at least from an immunological perspective. And upon ingestion, a range of secondary metabolites are produced, many of which are highly active as potent immune modulators. Chaga Polysaccharides effectively promote macrophage (white blood cell) activation through the MAPK and NF-κB signaling pathways, suggesting that Chaga Polysaccharides help regulate the immune response. The effectiveness of Chaga as an antiviral agent (as tested on West Nile virus and Herpes Simplex type 2 virus) has been shown to be dose dependent on the quantity of Chaga Polysaccharides present or their concentration. The antiviral results proved Chaga to be a very potent antiviral agent (rendering the viruses “completely inhibited.” This is why Chaga Polysaccharides content is set at such a high level in Dragon Herbs Wild Siberian Chaga — not less than 30%.
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Many of you already know about the transcription factor known as nuclear factor-kappaB (NF-kB), a molecule in all human cells that mediates virtually ALL disease, inflammation and death in humans. The suppression of this chemical is generally regarded as a means of reducing chronic and acute inflammation, degenerative and other kinds of disease, and to prolonging life. A Chaga-component known as DBL (3,4-dihydroxybenzalacetone) is a polyphenol derived Chaga. Chaga is used in Russian folk medicine to treat tumors, so investigators are exploring its mechanism of action. Because most genes involved in inflammation, anti-apoptosis (the blocking of natural cell death), and in cell proliferation — all of which are hallmarks cancer — are regulated by NF-kB, researchers postulated that DBL activity is mediated via modulation of the NF-kappaB activation pathway. They investigated the effects of DBL on NF-kB activation. They found that DBL suppressed NF-kB activation by a wide variety of inflammatory agents, including tumor necrosis factor (TNF), interleukin-1beta, epidermal growth factor, lipopolysaccharide and others. The suppression was cell type independent and inhibited both inducible and constitutive NF-kappaB activation. DBL inhibits I-kappa-B-alpha-kinase activity, I-kappa-B-alpha phosphorylation and degradation, p65 phosphorylation, and translocation, all of which are involved in NF-kB activation. DBL also suppressed the expression of TNF-induced and NF-kappaB-regulated proliferative, antiapoptotic, and metastatic gene products. These effects correlated with suppression of TNF-induced invasion. Together, these results indicate that DBL inhibits NF-kB activation and NF-kB-regulated gene expression. That’s a good thing!


http://www.ronsblogworld.com/?p=1850

Trouble to understand how it can be toghether immunosupporting and helpfull for psoriasis...

#32 brunotto

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Posted 02 February 2013 - 08:06 PM

Thanks, interesting progress. Are you tracking/measuring the effectiveness in terms of severity of the psoriasis?


I'm almost psoriasis free... but in the past I had a really severe psoriasis.

My regimen helps but also I do once a year some bath-puva sessions that dissolves all the psoriasis... then I stay clear for at least 5 months...

I did also the worm therapy
http://www.wormtherapy.com/

It was a difficult year to pass toghther with the worm (strong TH2 reactions) then I had to kill the worms... I had no immediate results but after having killed the worms I had bath-PUVA with extremely good and stable results (I had also my regimen started in the actual form after having killed the worms...)

Worms transformed at the end my psoriasis vulgaris into a pustolosis psoriasis (wich has something more close to do with athopic dermatitis and IS WORST)... but pustolosis psoriasis responded very good to bath-PUVA the went away and never popped up again. Psoriasis and pustular dermatitis can be triggered also by TNF-{alpha} inhibitors.

http://www.ncbi.nlm....pubmed/17310002

It looks like worms modified in a permanent way my TH1/TH2 balance... more towards TH2.
Then I take supps (and drugs) to keep it towards TH2.

As I get flu also some psoriasis pop out... its the virus fight that is TH1....

I know...mixing toghether thing doesnt make thing clear... but I'm not a researcher !
I know experimenthing this way can be not so lucky...

I had in the past a PCR to 1,5... now 0,35... so something had worked for sure (maybe all the things toghther... and actually one year ago it was at 0,76 and in this year I had bath-puva and my regimen)

Edited by brunotto, 02 February 2013 - 08:21 PM.


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#33 brunotto

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Posted 02 February 2013 - 08:30 PM

Update 02 Feb 2013


6.30 am

Orange juice & green tea:

1) 1800 mg LEF fish oil
2) LEF Super Ubiquinol CoQ10 100 mg
3) LEF Super K
4) BioPQQ, 20 mg
5) Asthaxanthin, 2 mg
6) Aspirin, 81 mg
7) Misoprostol (Cytotec), 200 mcg (defend the stomach from aspirin and other supps... it has also some antiinflammatory and kidney support properties)
8) Vitamine D3, 3000 UI (considered also the quantity of the multi)... now during sommer will reduce it.
9) Magnesium (dont know how much I put some magnesium chloride in tea)
10) Cognitex Basics (GPC-Choline 300 mg + Phosphatidylserine 50 mg)... looks like GPC-Choline not producing TMAO.
11) pregnenolone 25 mg only on sunday, tuesday and thursday
12) BHT 160 mg (reducing virus burden should also reduce the TH1 immunitary system stimulation, also positive effect on coaugulation)
13) Pomegranate Extract (dissolved in orange juice)

14) L-Tyrosine, 250 mg
15) L-Histidine 125 mg

45 min before lunch

1) Glycine 2000 mg
2) Lysine 1240 mg
3) Sam-e 200 mg
4) Half Two per day LEF tablet (a quarter of the raccomended dosage) (providing 100 ug folic acid + 75 ug B12 + 12 mg niacinammide.... others)
5) Forskolin 10 mg

6) Acetyl-L-Carnitine, 500 mg
7) L-Histidine 125 mg

45 min before supper

1) Glycine 2000 mg
2) Lysine 620 mg
3) Lithium Orotate 5 mg
4) Forskolin 10 mg

5) Vitamine C 750 mg

before sleep

1) Taurine, 2000 mg
2) pravastatin 10 mg

----------------------------------------------------

Misoprostol NOT for womans !!!

Also I take 1 strontium cap a week...

---------------------------------------------------

Moved moved Taurine and Pravastatin before sleep.

---------------------------------------------------
Please note.

My INR is at 0,99... so adding fish oil and aspirin for me is not a problem.
Other people may have too high INR by taking/adding aspirin and/or fish oil.

Edited by brunotto, 02 February 2013 - 08:59 PM.


#34 brunotto

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Posted 08 March 2013 - 10:48 AM

Update 08 Mar 2013


6.30 am

Orange juice & green tea:

1) 1800 mg LEF fish oil
2) LEF Super Ubiquinol CoQ10 100 mg
3) LEF Super K
4) BioPQQ, 20 mg
5) Asthaxanthin, 2 mg
6) On alternate days: (Aspirin, 81mg) or (Pentoxifylline, 400mg) (BUT NOT TOGHETHER)
7) Misoprostol (Cytotec), 200 mcg (only on Aspirin days)
8) Vitamine D3, 3000 UI (considered also the quantity of the multi)... during sommer will reduce it.
9) Magnesium (dont know how much I put some magnesium chloride in tea)
10) Cognitex Basics (GPC-Choline 300 mg + Phosphatidylserine 50 mg)... looks like GPC-Choline not producing TMAO.
11) pregnenolone 25 mg only on alternate days
12) BHT 160 mg (reducing virus burden should also reduce the TH1 immunitary system stimulation, also positive effect on coaugulation)
13) Pomegranate Extract (dissolved in orange juice)

14) L-Tyrosine, 250 mg
15) L-Histidine 125 mg
16) LEF MEGA GLA (piked up in offer)

45 min before lunch

1) Glycine 2000 mg
2) Lysine 620 mg
3) Sam-e 200 mg
4) Half Two per day LEF tablet (a quarter of the raccomended dosage) (providing 100 ug folic acid + 75 ug B12 + 12 mg niacinammide.... others)
5) Forskolin 10 mg

6) Acetyl-L-Carnitine, 500 mg
7) Vitamine C 750 mg

45 min before supper

1) Glycine 2000 mg
2) Lysine 1240 mg
3) Lithium Orotate 5 mg
4) Forskolin 10 mg

5) L-Histidine 125 mg
6) Pentoxifylline, 400 mg (only on NO aspirine days)
7) Pomegranate Extract

before sleep

1) Taurine, 2000 mg
2) pravastatin 10 mg

----------------------------------------------------

Misoprostol NOT for womans !!!

Also I take 1 strontium cap a week...

---------------------------------------------------

Take aspirine on alternate days becouse I had some little tinnitus problems (now gone).

Edited by brunotto, 08 March 2013 - 10:53 AM.


#35 niner

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Posted 08 March 2013 - 02:46 PM

brunotto, have you ever considered c60-olive oil? It has a significant effect on chronic inflammation. I had eczema that I was unable to completely get rid of over ten years, using conventional therapy. After a few months of c60 use, it is completely gone. Eczema isn't the same thing as psoriasis, but they both have an inflammatory component.

#36 brunotto

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Posted 04 May 2013 - 08:09 AM

brunotto, have you ever considered c60-olive oil? It has a significant effect on chronic inflammation. I had eczema that I was unable to completely get rid of over ten years, using conventional therapy. After a few months of c60 use, it is completely gone. Eczema isn't the same thing as psoriasis, but they both have an inflammatory component.

I'm usining it once a week (a teaspoon a week)... like vitamine c I cant use much of C60 becouse it's actually a pro TH1 supplement (it increase TNF-Alpha)... Eczema (atopic dermatitis) is actually pretty different from psoriasis... Atopic Dermatitis is a TH2 disease, Psoriasis is a TH1 disease.
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#37 brunotto

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Posted 04 May 2013 - 08:24 AM

Good results in alternating fish oil + aspirine and borage oil... works fine !


Update 04 May 2013


6.30 am

Orange juice & green tea:

1) 1800 mg LEF fish oil ON ALTERNATE DAY WITH 2600 mg Borage seed oil
2) LEF Super Ubiquinol CoQ10 100 mg
3) LEF Super K
4) BioPQQ, 20 mg
5) Asthaxanthin, 2 mg
6) Only on fish oil days: (Aspirin, 81mg)
7) Misoprostol (Cytotec), 200 mcg (only on fish oil days)
8) Vitamine D3, 3000 UI (considered also the quantity of the multi)... during sommer will reduce it.
9) Magnesium (dont know how much I put some magnesium chloride in tea)
10) Cognitex Basics (GPC-Choline 300 mg + Phosphatidylserine 50 mg)... looks like GPC-Choline not producing TMAO.
11) pregnenolone 25 mg only only on fish oil days
12) BHT 160 mg (reducing virus burden should also reduce the TH1 immunitary system stimulation, also positive effect on coaugulation)
13) Pomegranate Extract (dissolved in orange juice)
14) L-Tyrosine, 250 mg
15) L-Histidine 125 mg


45 min before lunch

1) Glycine 2000 mg
2) Lysine 1240 mg
3) Sam-e 200 mg
4) Half Two per day LEF tablet (a quarter of the raccomended dosage) (providing 100 ug folic acid + 75 ug B12 + 12 mg niacinammide.... others)
5) Forskolin 10 mg
6) Acetyl-L-Carnitine, 500 mg
7) L-Histidine 125 mg


45 min before supper

1) Glycine 2000 mg
2) Lysine 620 mg
3) Lithium Orotate 5 mg
4) Forskolin 10 mg
5) Pentoxifylline, 400 mg (only on Borage seed oil days that is aspirine free days )
6) Vitamine C 750 mg
7) Taurine, 1000 mg

before sleep

1) pravastatin 10 mg

----------------------------------------------------

Misoprostol NOT for womans !!!

Also I take 1 strontium cap and a teaspoon of C60 a week...

Edited by brunotto, 04 May 2013 - 08:32 AM.


#38 brunotto

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Posted 08 August 2013 - 09:03 AM

Update 08 August 2013


6.30 am

Orange juice & green tea:

1) 1800 mg LEF fish oil ON ALTERNATE DAY WITH 2600 mg Borage seed oil
2) LEF Super Ubiquinol CoQ10 100 mg
3) LEF Super K
4) BioPQQ, 20 mg
5) Asthaxanthin, 2 mg
6) Only on fish oil days: (Aspirin, 81mg)
7) Vitamine D3, 3000 UI (considered also the quantity of the multi)... during sommer will reduce it.
8) Magnesium (dont know how much I put some magnesium chloride in tea)
9) Cognitex Basics (GPC-Choline 300 mg + Phosphatidylserine 50 mg)... looks like GPC-Choline not producing TMAO.
10) pregnenolone 25 mg only only on fish oil days
11) BHT 160 mg (reducing virus burden should also reduce the TH1 immunitary system stimulation, also positive effect on coaugulation)
12) Pomegranate Extract (dissolved in orange juice)
13) L-Tyrosine, 250 mg
14) L-Histidine 125 mg


45 min before lunch

1) Glycine 2000 mg
2) Lysine 1240 mg
3) Sam-e 200 mg
4) Half Two per day LEF tablet (a quarter of the raccomended dosage) (providing 100 ug folic acid + 75 ug B12 + 12 mg niacinammide.... others)
5) Forskolin 10 mg
6) L-Histidine 125 mg


45 min before supper

1) Glycine 2000 mg
2) Lysine 620 mg
3) Lithium Orotate 5 mg
4) Forskolin 10 mg
5) Vitamine C 750 mg
6) Taurine, 1000 mg

before sleep

1) pravastatin 10 mg

----------------------------------------------------

Misoprostol NOT for womans !!!

Also I take 1 strontium cap and a teaspoon of C60 a week...
------------------------------------------------ dropped Acetyl-L-Carnitine, 500 mg... worried about TMAO concerns.... dropped Misoprostol, no need on alternating days aspirine... dropped pentoxyphilline

Edited by brunotto, 08 August 2013 - 09:56 AM.


#39 brunotto

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Posted 08 August 2013 - 10:34 AM

Update 08.08.2013 Corrected






6.30 am

Orange juice & green tea:

1) 1800 mg LEF fish oil ON ALTERNATE DAY WITH 2600 mg Borage seed oil
2) LEF Super Ubiquinol CoQ10 100 mg
3) LEF Super K
4) BioPQQ, 20 mg
5) Asthaxanthin, 2 mg
6) Only on fish oil days: (Aspirin, 81mg)
7) Vitamine D3, 3000 UI (considered also the quantity of the multi)... during summer will reduce it.
8) Magnesium (dont know how much I put some magnesium chloride in tea)
9) Cognitex Basics (GPC-Choline 300 mg + Phosphatidylserine 50 mg)...
10) pregnenolone 25 mg only only on fish oil days
11) BHT 160 mg (reducing virus burden should also reduce the TH1 system stimulation)
12) Pomegranate Extract (dissolved in orange juice)



45 min before lunch

1) Glycine 1000 mg
2) Lysine 1240 mg
3) Sam-e 200 mg
4) Half Two per day LEF tablet (a quarter of the recommended dosage)
5) Forskolin 10 mg
6) L-Histidine 125 mg
7) L-Tyrosine, 250 mg


45 min before supper

1) Glycine 3000 mg
2) Lysine 620 mg
3) Lithium Orotate 5 mg
4) Forskolin 10 mg
5) Vitamine C 750 mg
6) Taurine, 1000 mg
7) L-Histidine 125 mg


before sleep

1) pravastatin 10 mg




Edited by brunotto, 08 August 2013 - 11:21 AM.


#40 McGTak

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Posted 15 December 2013 - 08:22 AM

Do you have any psoriatic arthritis accompanying your osoriasis Brunotto? Would this regimen help with Psoriatic Arthritis too?

Do you have any psoriatic arthritis accompanying your osoriasis Brunotto? Would this regimen help with Psoriatic Arthritis too?

#41 brunotto

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Posted 26 January 2014 - 03:26 PM

IMHO it can help. But I do not havbe it.

UPDATED2014 ..................
6.30 am
Orange juice & green tea:
1) 1800 mg LEF fish oil ON ALTERNATE DAY WITH 2600 mg Borage seed oil
2) LEF Super Ubiquinol CoQ10 100 mg
3) LEF Super K only on fish oil days
4) Asthaxanthin, 2 mg
5) Only on fish oil days: (Aspirin, 81mg)
6) Vitamine D3, 3000 UI (considered also the quantity of the multi)... during summer will reduce it.
7) Magnesium (dont know how much I put some magnesium chloride in tea)
8) Cognitex Basics (GPC-Choline 300 mg + Phosphatidylserine 50 mg)...
9) pregnenolone 25 mg on alternate days
10) BHT 160 mg (reducing virus burden should also reduce the TH1 system stimulation)
11) Pomegranate Extract (dissolved in orange juice)
12) Half Two per day LEF tablet (a quarter of the recommended dosage)



45 min before lunch
1) Lysine 1240 mg
2) L-Tyrosine, 250 mg


45 min before dinner
1) Lysine 1240 mg

45 before bed
1) Glycine 2000 mg
2) Lithium Orotate 5 mg
3) Vitamine C 750 mg
4) Taurine, 1000 mg
5) pravastatin 10 mg


#42 brunotto

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Posted 26 January 2014 - 03:31 PM

Now my regimen is much less agressive becouse I feel much better....

#43 aribadabar

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Posted 11 February 2014 - 08:15 PM

Brunotto,

what is your take on using Chaga mushroom supplement in treating psoriasis?

Thanks!

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#44 Nick Kyz

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Posted 27 April 2014 - 05:17 PM

hey brunotto do you have an update for us? Things look promising so far.






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