hey brunotto, have you ever heard of chaga? i can't vouch for it with a personal testimonial, but i've read that it can be very effective for psoriasis (and overal health). probably worth looking in to.
No... but found this.
Research has supported the folk evidence that Chaga possesses potent immune supporting actions. Chaga is a rich source of β-glucans, especially 1-3-β-glucans, polysaccharides that are quintessential nutrients for the immune system. These polysaccharides have strong anti-inflammatory and immune balancing properties, enhancing the body’s ability to produce natural killer (NK) cells to battle infections. These polysaccharides are considered to be the primary active constituents of Chaga, at least from an immunological perspective. And upon ingestion, a range of secondary metabolites are produced, many of which are highly active as potent immune modulators. Chaga Polysaccharides effectively promote macrophage (white blood cell) activation through the MAPK and NF-κB signaling pathways, suggesting that Chaga Polysaccharides help regulate the immune response. The effectiveness of Chaga as an antiviral agent (as tested on West Nile virus and Herpes Simplex type 2 virus) has been shown to be dose dependent on the quantity of Chaga Polysaccharides present or their concentration. The antiviral results proved Chaga to be a very potent antiviral agent (rendering the viruses “completely inhibited.” This is why Chaga Polysaccharides content is set at such a high level in Dragon Herbs Wild Siberian Chaga — not less than 30%.
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Many of you already know about the transcription factor known as nuclear factor-kappaB (NF-kB), a molecule in all human cells that mediates virtually ALL disease, inflammation and death in humans. The suppression of this chemical is generally regarded as a means of reducing chronic and acute inflammation, degenerative and other kinds of disease, and to prolonging life. A Chaga-component known as DBL (3,4-dihydroxybenzalacetone) is a polyphenol derived Chaga. Chaga is used in Russian folk medicine to treat tumors, so investigators are exploring its mechanism of action. Because most genes involved in inflammation, anti-apoptosis (the blocking of natural cell death), and in cell proliferation — all of which are hallmarks cancer — are regulated by NF-kB, researchers postulated that DBL activity is mediated via modulation of the NF-kappaB activation pathway. They investigated the effects of DBL on NF-kB activation. They found that DBL suppressed NF-kB activation by a wide variety of inflammatory agents, including tumor necrosis factor (TNF), interleukin-1beta, epidermal growth factor, lipopolysaccharide and others. The suppression was cell type independent and inhibited both inducible and constitutive NF-kappaB activation. DBL inhibits I-kappa-B-alpha-kinase activity, I-kappa-B-alpha phosphorylation and degradation, p65 phosphorylation, and translocation, all of which are involved in NF-kB activation. DBL also suppressed the expression of TNF-induced and NF-kappaB-regulated proliferative, antiapoptotic, and metastatic gene products. These effects correlated with suppression of TNF-induced invasion. Together, these results indicate that DBL inhibits NF-kB activation and NF-kB-regulated gene expression. That’s a good thing!
http://www.ronsblogworld.com/?p=1850
Trouble to understand how it can be toghether immunosupporting and helpfull for psoriasis...