megastack advice
nootropic_rookie
28 Feb 2012
here's what i intend to test :
piracetam 50g
oxiracetam 20g
aniracetam 10g
pramiracetam 20g
nefiracetam 5g
bacopa monnieri 10g
fish oil 15g
vinpocetine 500mg
modafinil 1g
ginkgo biloba 5g
10 pills of alphabrain
picamilon 1g
alpha gpc 20g
noopept 2g
cerebrolysin 7500ml
huperzine A 2mg
magnesium 2g
methylene blue 500mcg
selenium 1mg
5 male multiple pills (multivitamins with lots of nutrients)
all that in one day, of course not at once, i will take all that throughout the day divided in 5-6 doses
it is also a very expensive stack overall for nefiracetam and noopept which cost a fortune so i want your advice about the efficiency of this stack and if I should add more things and maybe if its dangerous but i don't think it is the toxicity level is almost zero
so advices?
health_nutty
28 Feb 2012
hi folks, for months i've been studying many nootropics their toxicity and their benefits, i already trying lots of them and would like to push myself to the limits with a meganootropicstack to have my brain extremly powerful and maybe aim for mid term or long term effects
here's what i intend to test :
piracetam 50g
oxiracetam 20g
aniracetam 10g
pramiracetam 20g
nefiracetam 5g
bacopa monnieri 10g
fish oil 15g
vinpocetine 500mg
modafinil 1g
ginkgo biloba 5g
10 pills of alphabrain
picamilon 1g
alpha gpc 20g
noopept 2g
cerebrolysin 7500ml
huperzine A 2mg
magnesium 2g
methylene blue 500mcg
selenium 1mg
5 male multiple pills (multivitamins with lots of nutrients)
all that in one day, of course not at once, i will take all that throughout the day divided in 5-6 doses
it is also a very expensive stack overall for nefiracetam and noopept which cost a fortune so i want your advice about the efficiency of this stack and if I should add more things and maybe if its dangerous but i don't think it is the toxicity level is almost zero
so advices?
Is this a joke? There is a U shaped response curve to nootropics. It is not only dangerous but also counterproductive.
Baten
28 Feb 2012
> nefiracetam 5g
> methylene blue 500mcg
Nefiracetam at that dose is simply TOXIC to your testicles. don't do it.
The methylene blue is actually not all that "mega" big. I've taken 2mg doses myself. I wouldn't go much further though, big MAOI effects + possible effects on sperm quality.
As for the rest, I think it's simply unheard of. If you take all of that simultaneously you could just die, processing such big amounts of supplements/medicine is simply detrimental to your intestines.
Even trying them once at a time, as health_nutty said, after a certain point things don't get more effective with bigger doses, more so they become LESS effective and possibly TOXIC.
As a person approaching nootropics you should at least do the minimum of research, look at commonly prescribed doses; scientific databases, and finally anecdotal reports on forums.
Taking things lightly to such an extreme is simply playing around with your life. Do you want to get subtly sharper thoughts, or do you want to grow a brain tumor? Think twice before posting here again.
> alpha gpc 20ghi folks, for months i've been studying many nootropics their toxicity and their benefits
you can die of excess choline, maybe your body can cope and compensate, but especially in combination with AChEIs (Acetylcholinesterase Inhibitors), you could end up in a coma
> fish oil 15g
you'd probably be throwing up within 20 minutes (it's silly to take this much either way, there's a certain balance to things, you know?)
Did you do any research at all?
Edited by Baten, 28 February 2012 - 05:35 PM.
nootropic_rookie
28 Feb 2012
never heard of that U curve, can you explain? or give a way to calculate the exact amounts that are best. also i can't see how nootropic drugs which is not toxic and positive for the brain can actually be counterproductive?Is this a joke? There is a U shaped response curve to nootropics. It is not only dangerous but also counterproductive.
hum i didn't think about MAOI effect of methylene blue, it's very dangerous indeed, i will take this out of my stack.This might just be a troll thread, but let's take you serious for a moment
> nefiracetam 5g
> methylene blue 500mcg
Nefiracetam at that dose is simply TOXIC to your testicles. don't do it.
The methylene blue is actually not all that "mega" big. I've taken 2mg doses myself. I wouldn't go much further though, big MAOI effects + possible effects on sperm quality.
As for the rest, I think it's simply unheard of. If you take all of that simultaneously you could just die, processing such big amounts of supplements/medicine is simply detrimental to your intestines.
Even trying them once at a time, as health_nutty said, after a certain point things don't get more effective with bigger doses, more so they become LESS effective and possibly TOXIC.
As a person approaching nootropics you should at least do the minimum of research, look at commonly prescribed doses; scientific databases, and finally anecdotal reports on forums.
Taking things lightly to such an extreme is simply playing around with your life. Do you want to get subtly sharper thoughts, or do you want to grow a brain tumor? Think twice before posting here again.> alpha gpc 20ghi folks, for months i've been studying many nootropics their toxicity and their benefits
you can die of excess choline, maybe your body can cope and compensate, but especially in combination with AChEIs (Acetylcholinesterase Inhibitors), you could end up in a coma
> fish oil 15g
you'd probably be throwing up within 20 minutes (it's silly to take this much either way, there's a certain balance to things, you know?)
Did you do any research at all?
as for nefiracetam i know about the toxicity for testicles but i will counter it with tongkat ali which will compensate the effects and also the study is only on testicles of a dog nothing is yet proven for humans, knowing it is a nootropic i shouldn't really be scared about that.
I don't intend to take all that at once, it would be too much in my blood I know, I will merely cut that in many doses, as much as needed.
And what you're talking about? brain tumor? if that cause brain tumor then it shouldn't be nootropic anymore, whatever the dosage is, the excess supplements will be excreted by my kidneys and nothing else, nootropics are just supposed to activate receptors if they're in excess number they won't be used as all receptors are activated/modulated and they will be thrown out of my body and hardly cause a tumor.
as for choline I don't think I will die of excess, I already read testimonies of people taking up to 10g of choline and besides due to my amounts of racetams I'm just countering the use of acetylcholine by supplementing choline.
and 15g of fish oil is not that of a mega dosage, again I saw testimonies (on this forum) with people taking more than 10g and they didn't die, it's not as if you drank cooking oil.
again dosages are not of my concern, as you probably know the studies made on rats and lab animals use dosages 10 time more than what you take and those animals hardly died, I don't see why an human can't do that. I'm just concerned about possible interactions.
and if I have a problem I will just take activated charcoal to take all this out of my body.
DoomAndGloom
28 Feb 2012
Some quick things because I don't have the time to explain everything:
1. Just because something is called 'nootropic' doesn't mean its safe. In fact, plenty aren't understood in how they work, and this is especially true for new and experimental drugs.
2. Just because something 'only works on receptors' doesn't mean it can't kill you or harm you. And that isn't how all nootropics work.
3. Guess what nerve agents do, the ones that kill you and cause permanent neurological and nervous system damage? They inhibit acetylcholinesterase. Guess how Huperzine A works? Inhibiting acetylcholinesterase. Guess how much Huperzine A you are taking? 3,000 mcg. Most research doesn't even go above 400, and 400 is a pretty sizeable dose. Most people take 100 mcg. On top of that you're taking 20.6 grams of alpha GPC. Choline alone can be overdosed on, and alpha GPC is even worse since it readily crosses the BBB. The only way you could make this worse is throwing on more acetylcholinesterase inhibitors and some ALCAR to help the choline form into acetylcholine. Have fun with that.
4. Oh my god everything is in crazy doses.
Edited by DoomAndGloom, 28 February 2012 - 10:50 PM.
brainslugged
28 Feb 2012
never heard of that U curve, can you explain? or give a way to calculate the exact amounts that are best. also i can't see how nootropic drugs which is not toxic and positive for the brain can actually be counterproductive?
This is a sign that you don't fully understand what you are doing and need to do more research.
and if I have a problem I will just take activated charcoal to take all this out of my body.
From what I understand, activated charcoal does not do much except in the stomach, keeping the materials from being absorbed. If you take the stack and it is dangerous, by the time you are injured, it will be too late. There is no reset button.
Also, messing with the choline mechanisms too much is not a good idea and could be fatal as a previous poster said. If it kills you, there will certainly be no activated charcoal to come to the rescue and no recovering. Even if it is not fatal, there are studies that excess choline decreases life span in healthy individuals, and you would certainly be taking an excess.
kevinseven11
28 Feb 2012
nezxon
29 Feb 2012
Shorty
29 Feb 2012
months of research huh
renfr
29 Feb 2012
piracetam 50g - will make you competely manic
oxiracetam 20g - will kill your stomach
aniracetam 10g - will kill your kidneys
pramiracetam 20g - will kill your neurons
nefiracetam 5g - will kill your testicles
bacopa monnieri 10g - will cause stomach burns
fish oil 15g - will kill you of hemorragic stroke
vinpocetine 500mg - you will die of brain aneurysm
modafinil 1g - will kill your liver
ginkgo biloba 5g - you will die of aneurysm
10 pills of alphabrain - lots of huperzine A, B6 and bacopa which you already take, it will only increase your risk of dying
picamilon 1g - either neuropathy either aneurysm
alpha gpc 20g - wow either thrombosis or ischemic embolic stroke
noopept 2g - 200 times the recommended dose don't even want to think about the results
cerebrolysin 7500ml - cerebrolysin? that name sounds like brain destroyer
huperzine A 2mg - you will die of convulsions
magnesium 2g - coma or death
methylene blue 500mcg - yeah... a MAOI with racetams? best way to kill your brain
selenium 1mg - will die of selenosis
5 male multiple pills (multivitamins with lots of nutrients) - probably thrombosis
I wouldn't call that a megastack but rather a suicidal stack, not only you take massive doses but also you're mixing chemicals causing cumulative effects, seriously if you try that either you die either you go to the hospital and leave it with some kind of brain, liver, kidney disease and you will severely regret that.
Lower the doses down and reduce the number of chemicals in your stack, you're not pushing anything to the limits with that you're just making a deadly stack.
Baten
29 Feb 2012
Water soluble vitamins generally just get excreted at higher doses (to a certain degree, still not smart to overdo it),
but other vitamins/minerals are just plain toxic in too large of doses. Take 5 multis a day and you'll get VERY sick over time.
Edited by Baten, 29 February 2012 - 08:39 AM.
Tomas E
29 Feb 2012
victortsoi
29 Jul 2012
piracetam 50g - will make you competely manic
oxiracetam 20g - will kill your stomach
aniracetam 10g - will kill your kidneys
pramiracetam 20g - will kill your neurons
nefiracetam 5g - will kill your testicles
bacopa monnieri 10g - will cause stomach burns
fish oil 15g - will kill you of hemorragic stroke
vinpocetine 500mg - you will die of brain aneurysm
modafinil 1g - will kill your liver
ginkgo biloba 5g - you will die of aneurysm
10 pills of alphabrain - lots of huperzine A, B6 and bacopa which you already take, it will only increase your risk of dying
picamilon 1g - either neuropathy either aneurysm
alpha gpc 20g - wow either thrombosis or ischemic embolic stroke
noopept 2g - 200 times the recommended dose don't even want to think about the results
cerebrolysin 7500ml - cerebrolysin? that name sounds like brain destroyer
huperzine A 2mg - you will die of convulsions
magnesium 2g - coma or death
methylene blue 500mcg - yeah... a MAOI with racetams? best way to kill your brain
selenium 1mg - will die of selenosis
5 male multiple pills (multivitamins with lots of nutrients) - probably thrombosis
I wouldn't call that a megastack but rather a suicidal stack, not only you take massive doses but also you're mixing chemicals causing cumulative effects, seriously if you try that either you die either you go to the hospital and leave it with some kind of brain, liver, kidney disease and you will severely regret that.
Lower the doses down and reduce the number of chemicals in your stack, you're not pushing anything to the limits with that you're just making a deadly stack.
hey id like to revive this thread to ask, could you PLEASE give some descriptions of the catastrophes you've described? For example, why do you think 500mg of vinpo will cause aneurysm? Not disagreeing at all, just very curious. Thanks.
Introspecta
30 Jul 2012
Edited by joelski28, 30 July 2012 - 12:05 AM.
renfr
30 Jul 2012
Nootropic dosage of vinpocetine is around 5-20mg. Elderly patients with memory deficit are usually given between 70-100mg.piracetam 50g - will make you competely manic
oxiracetam 20g - will kill your stomach
aniracetam 10g - will kill your kidneys
pramiracetam 20g - will kill your neurons
nefiracetam 5g - will kill your testicles
bacopa monnieri 10g - will cause stomach burns
fish oil 15g - will kill you of hemorragic stroke
vinpocetine 500mg - you will die of brain aneurysm
modafinil 1g - will kill your liver
ginkgo biloba 5g - you will die of aneurysm
10 pills of alphabrain - lots of huperzine A, B6 and bacopa which you already take, it will only increase your risk of dying
picamilon 1g - either neuropathy either aneurysm
alpha gpc 20g - wow either thrombosis or ischemic embolic stroke
noopept 2g - 200 times the recommended dose don't even want to think about the results
cerebrolysin 7500ml - cerebrolysin? that name sounds like brain destroyer
huperzine A 2mg - you will die of convulsions
magnesium 2g - coma or death
methylene blue 500mcg - yeah... a MAOI with racetams? best way to kill your brain
selenium 1mg - will die of selenosis
5 male multiple pills (multivitamins with lots of nutrients) - probably thrombosis
I wouldn't call that a megastack but rather a suicidal stack, not only you take massive doses but also you're mixing chemicals causing cumulative effects, seriously if you try that either you die either you go to the hospital and leave it with some kind of brain, liver, kidney disease and you will severely regret that.
Lower the doses down and reduce the number of chemicals in your stack, you're not pushing anything to the limits with that you're just making a deadly stack.
hey id like to revive this thread to ask, could you PLEASE give some descriptions of the catastrophes you've described? For example, why do you think 500mg of vinpo will cause aneurysm? Not disagreeing at all, just very curious. Thanks.
I don't want to think what would happen with 500mg, vinpocetine is a strong vasodilator for the brain. There is a risk of aneurysm between the brain vessels and the rest of your body, vinpocetine being selective on brain blood vessels if there is too much differences in pressures and dilation of your vessels it might cause aneurysm or even a severe cranial hypotension.
I don't know really if 500mg IS deadly maybe higher doses are needed but considering that it is 5 times more than a therapeuthic dose I would advise caution on that.
victortsoi
30 Jul 2012
nootropic_rookie
30 Jul 2012
people say i'm stupid and i will kill myself but guess what i am still alive.
here is my report :
- late february, i started dosing and mixing up racetams at relatively low dose
- during march, i added several other nootropics in the megastack to see if it goes here what i kept in mind (i also added other things)
piracetam
oxiracetam
aniracetam
pramiracetam
nefiracetam
bacopa monnieri
fish oil
vinpocetine
modafinil
ginkgo biloba
picamilon
alpha gpc
noopept
huperzine A
magnesium treonite
selenium
glutamic acid
vitamin c
vitamin b1
sulbutiamine
L-theanine
rhodiola rosea
colloidal silver
melatonin
DHEA
siberian ginseng
caffeine
it stacked very well
- april and june i tried higher the dosage very slowly to extreme doses
i went 3 times to hospital because of extreme shaking, panic attacks and brain lesion but it went fine i don't think it's bcz of the stack the week after the hospital i tried the megadosage and went very fine
i had extreme diarrhea too and wouldn't stop for a whole month i reduced ginkgo biloba and bacopa dosage and it work
i also had extreme insomnia for over 2 weeks i dont know the time i didn't see time pass, i couldn't sleep one minute during megadosage for over 2 weeks
the insomnia didn't impair my brain but i lost all my past memories those longer than 5 years but the rest is very fine
it went down after the two week i could sleep 2h a day
i continued upping dosage in july and today i can sleep 3h-4h a day and im very fine
the only inconvenient is the price, it was many hundreds euros a month which is not a lot for my job but now i started buying bulk product from china in higher dose to pay less.
today is 30july and here it is my stack as of today : (everything is split 6 times in the day)
piracetam 48g
oxiracetam 15g
aniracetam 10g
pramiracetam 8g (cannot go more or else i have seizure)
nefiracetam 3g (as someone say no it didn't kill my testicle its very fine but testicles are somewhat smaller)
bacopa monnieri 3g
fish oil 15g
vinpocetine 150mg
modafinil 500mg
ginkgo biloba 1g
picamilon 2g
alpha gpc 16g
noopept 2g
huperzine A 1mg
magnesium treonite 5g
selenium 200mcg
glutamic acid 10g (i wanted to put 20g but it make me shake)
vitamin c 5g
vitamin b1 500mg
sulbutiamine 4g
L-theanine 5g
rhodiola rosea 800mg
colloidal silver 15ppm
melatonin 5mg
DHEA 25mg
siberian ginseng 1g
caffeine 3g
i will maybe reduce dosage if i have not enough money but it is going well for now, effect :
- past memory is lost i can't remember of it
- not a lot of sleep most is 4h
- extreme mobility and hearing can do cognitive task very fastly and understand easily
- extreme ringing in ear
- sexual dysfunction
- i have a mild blue skin
- sometime i feel my heart will explode but it don't
- brain lesions according to neurologist but brain work fine so i don't care
- i went to hospital 22 july because of uncontrollable moves and brain racing thought, i had kidney disfunction too they cleansed kidney with dialysis and now i take phylantus niruri for kidney problem it work a lot
- i am much more social but also very violent agressive
- i have red dots under my eyes
my cognitive abilities are very well but my memory is very bad i think i lost it i have very poor short term and long term memory
i think i will stop or reduce dosage, or maybe higher dosage to correct damage, can you guide me?
i will see how it go for the moment it's very good
Kahnetic
30 Jul 2012
i will maybe reduce dosage if i have not enough money but it is going well for now, effect :
- past memory is lost i can't remember of it
- not a lot of sleep most is 4h
- extreme mobility and hearing can do cognitive task very fastly and understand easily
- extreme ringing in ear
- sexual dysfunction
- i have a mild blue skin
- sometime i feel my heart will explode but it don't
- brain lesions according to neurologist but brain work fine so i don't care
- i went to hospital 22 july because of uncontrollable moves and brain racing thought, i had kidney disfunction too they cleansed kidney with dialysis and now i take phylantus niruri for kidney problem it work a lot
- i am much more social but also very violent agressive
- i have red dots under my eyes
i will see how it go for the moment it's very good
With those symptoms, how on Earth can you say this regimen is going well? Surely no one is foolish enough to persist despite such dramatic and detrimental effects.
nootropic_rookie
30 Jul 2012
i don't recommend this stack to anyone but for me it is great i won't use it forever but i appreciate it
renfr
30 Jul 2012
Picamilon more potent vasodilator as vinpocetine? Are you sure? I use take my vinpocetine in Neurostim, a blend sold by Mindnutrition, I wonder why they put vinpocetine instead of picamilon. To me I didn't feel anything particular vasodilation-talking with picamilon while with vinpocetine I can clearly feel the effects.THe reason I ask is because I sometimes combine picamilion (which is supposed to be a way more potent vasodialator than vinpocetine) with alcar. I think the vaso-dialation and constriction that our noots do inside our brains is too often overlooked when discussing safety. I find your descriptions witty and fascinating, would like to hear your rationale for some more of these :O
But I guess that's because picamilon is bodywide while vinpocetine is centered in the brain.
I've always thought picamilon was a stupid russian nootropic, I found it totally ineffective until I realize it is very potent for meditation and mind alteration, it makes binaural beats as strong as isochronic tones really! Maybe the same effects can be reached with alcohol or any other GABA agonist but that's picamilon that strongly changed my EEG.
Honestly I don't think that taking picamilon or vinpocetine at normal doses will do anything harmful in the domain of vasodilation. However possible side-effects of moderatly too much vasodilation is for instance running nose. I experience that sometimes when I take too high doses of ginkgo biloba.
It can also cause insomnia, vasoconstriction does too, why? I don't really see why but I guess it's because much more nutrients reach the brain due to more bloodflow overall excitatory neurotransmitters such as ephedrine, dopamine and so on that stimulates your brain.
I already took several vasodilators, not drugs specifically meant to vasodilate but several drugs that all have vasodilatory actions and it didn't cause me any potential harm.
I think that anyway vasodilation is usually needed for a lot people, for people living in cold countries (cold causes vasoconstriction and heat vasodilation) but also for people who take coffee and many other drugs that cause vasoconstriction. (ibuprofen for example)
You can go on this mix, picamilon will never be too much vasodilating, it's vasodilating properties are likely due to its action on GABA and nothing else.
This nutty took 2g of picamilon and honestly I almost reached those dosages and it didn't harm me at all. I wonder if picamilon is truly something worth it, probably another CCCP made drug to praise Mother Russia. They already made that with phenibut, most useless drug to me ever made. However noopept is a real success.
Jesus, you've gone totally insane. Go heal yourself please. Stop the craziness and taper the damn stack and go to ER get some help.i went 3 times to hospital because of extreme shaking, panic attacks and brain lesion but it went fine i don't think it's bcz of the stack the week after the hospital i tried the megadosage and went very fine
i had extreme diarrhea too and wouldn't stop for a whole month i reduced ginkgo biloba and bacopa dosage and it work
i also had extreme insomnia for over 2 weeks i dont know the time i didn't see time pass, i couldn't sleep one minute during megadosage for over 2 weeks
the insomnia didn't impair my brain but i lost all my past memories those longer than 5 years but the rest is very fine
it went down after the two week i could sleep 2h a day
i continued upping dosage in july and today i can sleep 3h-4h a day and im very fine
the only inconvenient is the price, it was many hundreds euros a month which is not a lot for my job but now i started buying bulk product from china in higher dose to pay less.
Brain lesions, WTF are you serious man? And it doesn't bother you more than that? Gosh, you destroyed your brain and let me tell you this damage is irreversible.
Don't you realize how much glutamatergic bullshit you've taken? Glutamate at mild doses is good for your memory but when it comes in excess it destroys your cells, that's excitoxicity and no wonder why you sleep 3 hours the night only, your neurologic system is completely fucked up.
The best you can do is stop making more brain damage before those brain lesions become holes.
Edited by renfr, 30 July 2012 - 11:05 PM.
Deckah
30 Jul 2012
BUT.... This is obviously a joke..
Looks like it got lost in the wind, maybe a mod will pick it up.
gamesguru
31 Jul 2012
victortsoi
31 Jul 2012
nootropic_rookie
03 Aug 2012
last day i take some dxm to feel better and it is gone wrong very very wong
i feel i have intense brain damage i can't think properly i forgot things i have bad vision kind of blurry my tinnitus is stronger than ever and i can't even follow conversation with people help me i'm screwed i tried my megastack and it does nothing!!!
all i get is little less brian fog this story is becoming a real nightmare
i will see my neurologist asap tomorrow i think to check my brainsz
i have read that dxm brain damage can be cured with dxm itself, is this true? i don't want to destroy my brains
please do you have a stack to go back or something like that i have made a big error this stack is bullshit
i can't go cold turkey or i will die i will taper in one week i hope it goes well
the extent of brain damage is too sevee to be ignored, dxm is killing me, i can't even remember my credit card number and took me minutes to remember my birthdate
and no guys this isnt a joke i am serious this stuff is being lethal right now
please give advice and help
1thoughtMaze1
03 Aug 2012
HELP
last day i take some dxm to feel better and it is gone wrong very very wong
i feel i have intense brain damage i can't think properly i forgot things i have bad vision kind of blurry my tinnitus is stronger than ever and i can't even follow conversation with people help me i'm screwed i tried my megastack and it does nothing!!!
all i get is little less brian fog this story is becoming a real nightmare
i will see my neurologist asap tomorrow i think to check my brainsz
i have read that dxm brain damage can be cured with dxm itself, is this true? i don't want to destroy my brains
please do you have a stack to go back or something like that i have made a big error this stack is bullshit
i can't go cold turkey or i will die i will taper in one week i hope it goes well
the extent of brain damage is too sevee to be ignored, dxm is killing me, i can't even remember my credit card number and took me minutes to remember my birthdate
and no guys this isnt a joke i am serious this stuff is being lethal right now
please give advice and help
HA HA HA HA, this is so obviously a troll thread.
nootropic_rookie
03 Aug 2012
i already diminished by megastack and it does nothing for the moment.
i will go to neurologist see what he say if he give me nothing i will take a shot of dxm again as a last chance to ever recover.
i have f*cking brain lesions dude how can you laugh of that!! i totally screwed myself and i regret it i thought my body was made of steel but now i figured out it's not i don't know how much time it will take to recover, months years? maybe i will never recover, i'm too young to face that all my life
i will try eveyrthing just tell me what to try
i read iv vitamin c can recover brain damage and combat brain cancerous lesions, how do i get iv vitamin c?
i will maybe just buy vitamin c tablet and take something like 100g to annihilate damage
please advice and help and stop laughing this is freakin serious folks


