This is only a prelinary report (and the combo is not cheap) but forget Pram, a combination of Heat (an avant supp) and "glucophase" made by designer supplements taken together on an empty stomach works VERY well.
The ingredients in heat (which is designed to assist in weight loss) are:
Hordenine, Evodiamine, Alpha-yohimbine, and Tyramine
http://www.mindandmu....php?pageID=235
The ingredients in glucophase are: (q=quercetin dervivative)
K-R-Ala (Potassium-R-Lipoate)..........250mg
D-Biotin..........500mcg
Quercetin...........200mg
Q3D.....24mg
Q4D........25mg
There have been threads at avant discussing how something(s) in glucophase increases permeability of the BBB allowing the heat to have this effect. Heat does make some people warmer, and perhaps one would need to figure out the "active" ingredient (tyramine? which 1fast has recently gotten in bulk).
If you are going to get tyramine and try this, see avant thread on tyramine as there are apparently storage issues.