Any way to counteract brain fog from myo-inositol? Would choline help?
LongeCityAdvocacy & Research for Unlimited Lifespans
Inositol brain fog
Started by
nickygstar
, Jun 10 2012 03:23 PM
2 replies to this topic
#2 Guest_Funiture2_*
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Posted 19 June 2014 - 11:47 AM
I am also experiencing a bit of brainfog from inositol, did you ever end up fixing it? Did choline help counteract the brainfog? I read somewhere that choline and inositol are both precursors to myelin sheath or maybe it was some sort of brain phospholipid. I'm thinking that high amounts of inositol may deplete choline. Though "deplete" might be the wrong way to put it. I suspect the increased inositol intake allocates equal amounts of choline to synthesize the myelin sheath and in the process, takes away from one of the other uses of choline. I know that choline can be used in 4 different pathways in the body, can't remember the specific functions though.
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#3 Guest_Funiture2_*
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Posted 19 June 2014 - 07:10 PM
wanted to repost with a bit more information:
I think that inositol may be resulting in a decrease in acetylcholine production. I found out, from this article (http://advances.nutr...ent/1/1/46.full) that Choline can be used to
- create acetylcholine
- create phospholipids
- act as a methyl donor (there might be a 4th pathway)
I suspect that taking Inositol would move an equal amount of Choline towards phospholipid production (since inositol and choline are both phospholipid precursors) and away from acetylcholine production resulting in brain fog, a decrease in appetite (some people take choline and experience a huge increase in hunger), and other side effects. I myself have been experiencing brain fog and decreased verbal fluidity when taking Inositol without a choline source. It has also had a slight antidepressant effect which is nice and is congruent with my theory since since compounds with anti-cholinergic properties are known to cause euphoria and too much choline usually results in depression.
This is a link to my thread posing the same question:
http://www.longecity...ne/#entry669802
if anyone is experiencing side effects from Inositol alone try adding a choline source and let me know how it goes!!!
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