3 replies to this topic

[Balmung]

Has anybody gone over this study? www.scirp.org/journal/PaperDownload.aspx?paperID=20590

Deals with baby hamsters and c60, any reason to worry?

[smithx]

This should be moved to the C60 health forum, but here's the abstract.

ABSTRACT
Research on biological effects of C60 and its derivatives is one of the hotspots in the area of biological effects of nano- materials. Compared with surface-modified C60 derivatives, reports on the biological effects of unmodified pristine C60 are relatively less. This work aimed to investigate the interaction between baby hamster kidney cells and pristine C60 in solution. The C60 suspension was prepared using solvent exchange method and characterized by UV spectro-photometry, electronic transmission microscopy and dynamic light scattering techniques. The baby hamster kidney cells were incu-bated with different concentrations of C60 suspensions, and light microscopy, cell counting kit 8 assay, and acridine orange staining were used to observe the cell growth and morphology. The results showed that C60 could inhibit the cell growth and induce cell apoptosis with a dose-effect relationship. C60 might enter cells and the possible way it enters cells were also proposed

The key point may be:

From the DLS measurement, it can be seen that the nC60 nanoparticle were mainly distributed in the range of 105 - 290 nm with an average particle size of 175.8 nm. From the TEM images, most of the nC60 nanoparti- cles were gathered and roughly round shaped with a size distribution of 50 - 120 nm (Figure 2(b) (up)). Some nC60 nanoparticles had small size distributions, about 5 - 10 nm and even smaller (Figure 2(b) (down)). The above results indicated that pristine C60 was in the form of rough round particles with a wide size distribution.

C60 is actually about 1nm, so they were dealing with clumps of it, not dissolved C60.

I am waiting to ingest it myself until we get a larger study showing benefits, though.

Edited by smithx, 26 October 2012 - 07:36 AM.

[Andey]

For me it looks like use of muller is way to go. (as shown here http://www.longecity...post__p__539645)

If you get C60 from SES it appears that different purity have different powder sizes. Thats why 99.5% dissolves very quickly and 99.95 can be stirred for month.
So muller can help with size of clusters and you can dissolve you very quickly with probably better quality.

[niner]

Has anybody gone over this study? www.scirp.org/journal/PaperDownload.aspx?paperID=20590

Deals with baby hamsters and c60, any reason to worry?

It wasn't actually baby hamsters, it was a particular type of cell that came from baby hamsters. That's important, because it's a lot easier (a LOT easier) to either cause problems or make good things happen when you're dealing with cells in a test tube. When you're dealing with a living animal and dosing orally, there are multiple systems standing between your drug and whatever effect you saw in the test tube. Those systems have evolved over eons to keep non-nutritive chemicals out of the body, and they work really well. Things that work with cells in a test tube hardly every behave the same way in a live animal.

As a comparison experiment, mice given huge doses of C60 suspended in oil (not dissolved or reacted) daily for a month were not harmed. (source)

So I'm not particularly concerned. If there are any nano-clusters of C60 in olive oil, they will probably react pretty quickly anyway.