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[medievil]

Taltirelin


From Wikipedia, the free encyclopedia


Taltirelin Systematic (IUPAC) name N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide Clinical data AHFS/Drugs.com International Drug Names Pregnancy cat. ? Legal status ? Routes Oral Identifiers CAS number 103300-74-9
201677-75-0 ATC code None PubChem CID 656609 UNII DOZ62MV6A5 Synonyms (4S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide Chemical data Formula C₁₇H₃₁N₇O₉ Mol. mass 477.46 g/mol

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Taltirelin (marketed under the tradename Ceredist) is a thyrotropin-releasing hormone (TRH) analog, which mimics the physiological actions of TRH, but with a much longer half-life and duration of effects,^[1] and little development of tolerance following prolonged dosing.^[2] It has nootropic,^[3] neuroprotective^[4] and analgesic effects.^[5]
Taltirelin is primarily being researched for the treatment of spinocerebellar ataxia; limited research has also been carried out with regard to other neurodegenerative disorders, e.g,, spinal muscular atrophy.^[6][7][8]

http://en.wikipedia....wiki/Taltirelin


yawn thats most for tonight, need to do some more research on them all and elaborate more but again a few new goody's that havent been discussed here yet.

[drug]

SWIM got 1 gram with friend - its very difficult to get, almost impossible. SWIM and his friend tried and it made them very sleepy - perhaps because of GABA release? http://jp.physoc.org/content/577/2/497

Perhaps prolonged use will show some nice effects.