GEBR-7b is a highly selective PDE4D inhibitor. In recent studies, it's been shown to enhance memory. It boosts extracellular levels of cAMP in the hippocampus of up to 40%. Unlike Rolipram, it doesn't cause emesis at memory enhancing doses. And it's also 3-10x more potent than Rolipram. More info can be found here: http://www.ncbi.nlm....les/PMC3246667/.
The best part is while GEBR-7b is a research chemical, it is cheaper than the traditional CILTEP stack (Forskolin, Zembrin, Artichoke).
This American (Not Chinese) company can synthesize 5mg of GEBR-7b for $100. The optimal dosage in rats is .001mg/kg-.003mg/kg. So for a human weighing 80kg, that would be between .006mg-.018mg/d. At the highest positive dose used every day, 5mg would last 277 days. Here is the manufacturer: http://www.millipore...item/524748-5mg. We could negotiate a price drop if we group buy this thing. 277 days is a long time so if you wanted to only experiment with it for only ~5 months, you could split it with someone and pay $50 instead of $100. What do you guys think?
One downside is that GEBR-7b is administered through injection. So a syringe/needle, bacteriostatic water, and vials will be required for trialing. Researchers in the study linked above only tested for object recognition and spatial memory. So other forms of memory weren't considered.
Edited by KoolK3n, 24 July 2013 - 12:24 AM.