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Cerebrolysin Nasal Spray

cerebrolysin

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#91 Dale Taylor

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Posted 24 August 2013 - 08:02 AM

You can pour the cerebrolysin off the vial with some effort using the soaking hose of nasal spray which I done :) I also thought that it will pour when breaking off, but its not the case, cerebro is somewhat dense in order to get it from thin orifice. Also some basic pipette can be used to do the work.


Thanks for the info. will look into getting some then.

#92 eno

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Posted 24 August 2013 - 12:16 PM

Can someone tell me if you would need a needle to get the stuff out of the Vials? Or is it pourable? I love to try this stuff but just can't have needles about the place due to being an x drug user.

Was planing on using it in a nasal pump spray.


You can pour the cerebrolysin off the vial with some effort using the soaking hose of nasal spray which I done :) I also thought that it will pour when breaking off, but its not the case, cerebro is somewhat dense in order to get it from thin orifice. Also some basic pipette can be used to do the work.


I use a pump sprayer of a saline nasal spray together with a 10 mL vial of Cerebrolysin, following this procedure:

Open the sprayer. It has a robust snap-in mechanism. May need pliers and some force.
Pour the salt water out. Flush the container and the spraying mechanism with sterile water.
Pour the Cerebrolysin into the container. It worked by jolting the vial, no need for a syringe or pipette here.

I store the spray in the fridge. To keep it clean I wipe it with alcohol with each use as suggested by AuralAnomaly:

For now maybe a simpler cheaper way to avoid contamination to some extent is to simply decompress the spray ejector only after pulling it out from the nasal passages and wiping the tip with an alcohol swab?


I'm pretty confident that the brain juice stays in good condition for a week or two this way.

Edited by eno, 24 August 2013 - 12:26 PM.

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#93 Shay

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Posted 26 August 2013 - 10:55 PM

Sorry if I'm dupilcating, I haven't found anything via searching. What about sublingual?

#94 vlk

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Posted 27 August 2013 - 08:58 AM

If it can be absorbed into the blood via capillaries in the nose, then sublingual might work too.

However, the main benefit of intranasal is not just the absorption into the blood, but the direct transfer of cerebrolysin through the olfactory neurons straight into the brain!

Edited by vlk, 27 August 2013 - 08:59 AM.


#95 archangel

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Posted 27 August 2013 - 03:49 PM

However, the main benefit of intranasal is not just the absorption into the blood, but the direct transfer of cerebrolysin through the olfactory neurons straight into the brain!


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#96 Krabby

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Posted 27 August 2013 - 06:22 PM

I'm having a really hard time administering the dose.
I'm testing with water first and it either all comes out of the front of my nose or goes down my throat.

Is there any position you guys are using?
I am thinking of using a smaller dose.

#97 kobokok

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Posted 28 August 2013 - 09:15 AM

I'm having a really hard time administering the dose.
I'm testing with water first and it either all comes out of the front of my nose or goes down my throat.

Is there any position you guys are using?
I am thinking of using a smaller dose.


I find that dropping cerebrolysin lying on the bed with the head hanging over the edge works quite well. This position makes me a bit dizzy after though.

If you're dropping with a syringe pulling and pushing the plunger prior dropping helps avoid "sudden large doses".

#98 Psionic

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Posted 28 August 2013 - 09:41 AM

Also spraying and then lean head back over a pillow or a seat for a few minutes in order to get direct transfer through olfactory bulb into the brain :-)

Anyone tried with chitosan yet?

#99 Krabby

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Posted 28 August 2013 - 03:28 PM

Thanks guys, it worked a lot better even thought it hurt a lot more :).
I'm using a mirror so I can put the MAD300 in at the right angle.

I finally took my first dose so I hope to report back sometime in the future.

#100 dannyfc

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Posted 28 August 2013 - 09:12 PM

So am I right in assuming directly syringing Cerebrolysin into the nostril will have similar potency to injection?

#101 Krabby

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Posted 28 August 2013 - 11:57 PM

edit: sorry

Edited by Krabby, 29 August 2013 - 12:07 AM.


#102 Krabby

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Posted 29 August 2013 - 12:02 AM

edit: double sorry

Edited by Krabby, 29 August 2013 - 12:07 AM.


#103 MasterHerb

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Posted 30 August 2013 - 08:50 PM

Updates?

#104 Krabby

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Posted 30 August 2013 - 09:23 PM

I have taken it three days in a row. I'm not really sure if I feel anything positive as of right now but i'm pretty sure something has changed.
However, using the MAD300 is the most painful thing I have done in a very long time. I don't know if I am using it wrong or what but it is like getting water up your nose in a swimming pool x10.
vlk, how are you applying it with the MAD? I tip my head over a pillow like others suggested which works well for absorption (I think) but it does hurt like hell.

#105 vlk

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Posted 31 August 2013 - 06:38 PM

I have taken it three days in a row. I'm not really sure if I feel anything positive as of right now but i'm pretty sure something has changed.
However, using the MAD300 is the most painful thing I have done in a very long time. I don't know if I am using it wrong or what but it is like getting water up your nose in a swimming pool x10.
vlk, how are you applying it with the MAD? I tip my head over a pillow like others suggested which works well for absorption (I think) but it does hurt like hell.


I am trying with chitosan now, I can't say I notice any difference in effects yet, but the addition of the chitosan makes it more viscous so it atomises a bit better at the same flow rate and very little if any goes down my throat.
The most I have (successfully) administered in one go is 0.3ml per nostril, but I think I could do quite a bit more with the chitosan, and I will increase the dose next week. How much are you using?

I assume the burn is from the small amount of sodium hydroxide, and it seems to be a reasonable indicator that you are getting the cerebrolysin to the right place...
Honestly, I quite like the burn as a sign I've got it right, although it does make my eyes water a bit sometimes!

The position that I find best is the "praying to Mecca" position with the top of my head resting on the floor. Not particularly comfortable, but that works best for me :laugh:
One point to note is that I have have fairly narrow nasal passages and some scar tissue inside my nose from an operation when I quite young, so other people may have more luck with different positions than I have.

#106 MasterHerb

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Posted 01 September 2013 - 06:36 PM

Does anyone else have problems with their mad measurement lines fading out? I clean using hydrogen peroxide....that might be the culprit.

#107 Psionic

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Posted 01 September 2013 - 07:09 PM

Masterherb: Yes the measurement is gone and I am using only distiled water so your peroxide isnt the reason:)

The experiences with 1:1 ratio cerebrolysin:distilled water, 2ml of the solution applied twice daily with head upside down and hold for at least 5 mins. The results can be described as increased mental stamina and accuracy with slighty elevated self-confidence for following 2 hours and then slowly fading down... I am not thinking of it being a placebo as my game and other skills performance is really more sharp-executen, without any unnecessary faults (just a side note that influence of alcohol seems to stay below limits). Theres are also some moments or flashes from past memories and dreams are somewhat amazing, I dont say its not something a healthy person cant remark, but something is happening there.

Also when using nasal spray bottle, the cerebrolysin degrades vastly and only after 24hours stored in the fridge there is recognizable different taste of the substance and I am not considering it safe to ingest. When stored in another closed syringe with almost no air, it seems to stay fresh for at least three days (not tested more).

BTW: I am dosing 250mcg methylfolate and 500mg B1 over the course of whole day so it can influence perceived results a little too.
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#108 MasterHerb

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Posted 01 September 2013 - 07:20 PM

Masterherb: Yes the measurement is gone and I am using only distiled water so your peroxide isnt the reason:)

The experiences with 1:1 ratio cerebrolysin:distilled water, 2ml of the solution applied twice daily with head upside down and hold for at least 5 mins. The results can be described as increased mental stamina and accuracy with slighty elevated self-confidence for following 2 hours and then slowly fading down... I am not thinking of it being a placebo as my game and other skills performance is really more sharp-executen, without any unnecessary faults (just a side note that influence of alcohol seems to stay below limits). Theres are also some moments or flashes from past memories and dreams are somewhat amazing, I dont say its not something a healthy person cant remark, but something is happening there.

Also when using nasal spray bottle, the cerebrolysin degrades vastly and only after 24hours stored in the fridge there is recognizable different taste of the substance and I am not considering it safe to ingest. When stored in another closed syringe with almost no air, it seems to stay fresh for at least three days (not tested more).

BTW: I am dosing 250mcg methylfolate and 500mg B1 over the course of whole day so it can influence perceived results a little too.


I transferred my cere into an amber glass bottle....are you saying that you should toss it out after 3 days even if you refrigerate it?

I am also experiencing a dull headache.....anyone else noticing this? I am taking .5ml per nostril...I will try to lower the dose to .3

Edited by MasterHerb, 01 September 2013 - 07:23 PM.


#109 Psionic

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Posted 01 September 2013 - 07:37 PM

I didnt tested it after 3 days, as I am using 5ml cerebrolysin capsules they lasts exactly 2.5 days (60 hours) and even the last dose seems to be in same quality as the first one if stored in another enclosed syringe.

#110 Krabby

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Posted 01 September 2013 - 08:15 PM

I am using 5ml ampules and I use Clingfilm to cover the vial over when I put it in the fridge. Previously I have taken 1ml out of it daily, I might now try and keep it all in the syringe like you have suggested.

I too seem to have a dull headache throughout the day, I’m not sure if this is due to the fact I have been lying upside down for a while or if it’s the medicine. It seems to loom over me a bit but it's nothing too noticeable if I don't think about it.

When do you guys dose the cerebrolysin? I have been doing it at 12 – 1pm but now I’m thinking that it might be more effective to do it before bed in order to get maximum repair of the brain during sleep. Anyone got any insight on this?

#111 MasterHerb

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Posted 01 September 2013 - 09:52 PM

I am using 5ml ampules and I use Clingfilm to cover the vial over when I put it in the fridge. Previously I have taken 1ml out of it daily, I might now try and keep it all in the syringe like you have suggested.

I too seem to have a dull headache throughout the day, I’m not sure if this is due to the fact I have been lying upside down for a while or if it’s the medicine. It seems to loom over me a bit but it's nothing too noticeable if I don't think about it.

When do you guys dose the cerebrolysin? I have been doing it at 12 – 1pm but now I’m thinking that it might be more effective to do it before bed in order to get maximum repair of the brain during sleep. Anyone got any insight on this?


I am taking mine around the same time.....so is this headache due to nasal administration or do people to take it IV/IM have the same side effect?

#112 Krabby

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Posted 01 September 2013 - 10:01 PM

I am taking mine around the same time.....so is this headache due to nasal administration or do people to take it IV/IM have the same side effect?


No idea. To be honest I have not read too much about the substance.
I just hope it will work over time to give me some benefit.

#113 Godof Smallthings

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Posted 02 September 2013 - 11:13 AM

Make sure you engage in habits that build positive neural networks...

Personally, I would try to apply mindfulness at all times I could manage, meditate, and think happy thoughts....

Remember that it is what you prime your brain for, that it will tend to do (best) as a baseline... so if you're jerking off to porn or playing video games, maybe try to find some habits you'd rather have.

Simple way to test validity of habit: how will this habit affect your life overall? How will you feel about this habit when you lie on your deathbed?
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#114 Mr Matsubayashi

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Posted 02 September 2013 - 11:40 AM

First day on Up-ya-nose Cere

Applicator is a cheap disposable spray bottle from ebay. Some solution does try to exit my nose on the front side and later succeeds in going down the back of my throat. Tastes gross. I will need to look into this more diligently like many of you already have. I have not diluted or in any other way modified the solution.

The effects feel like the Cere i know. All in all, this is a win over injections. It will take a month before I'm convinced entirely. Provided the applicator doesn't make you look like a druggy this may be a way to keep the peak effects sustained all day. A second but less important win is how much cheaper this is.
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#115 vlk

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Posted 02 September 2013 - 12:48 PM

Make sure you engage in habits that build positive neural networks...
[snip]


Some very good advice, I often find that at times when I'm most stressed I spend a lot of time engaging in unproductive habits that only make things worse.
Any nootropic chemical or or method can only be an aid to recovery, not the entire solution.



To everyone using nasal spray bottles -
These are normally used by shaking them to produce a foam, then keeping the bottle upright and spraying the foam up the nose.
Is this what you are doing, or are you using them upside down? How well is it working? Do you feel a burn when it gets in your nose?



As for headaches, I have not experienced any yet, apart from the bloodrush due to crouching with my head on the ground for a minute!

#116 MasterHerb

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Posted 02 September 2013 - 03:08 PM

First day on Up-ya-nose Cere

Applicator is a cheap disposable spray bottle from ebay. Some solution does try to exit my nose on the front side and later succeeds in going down the back of my throat. Tastes gross. I will need to look into this more diligently like many of you already have. I have not diluted or in any other way modified the solution.

The effects feel like the Cere i know. All in all, this is a win over injections. It will take a month before I'm convinced entirely. Provided the applicator doesn't make you look like a druggy this may be a way to keep the peak effects sustained all day. A second but less important win is how much cheaper this is.


How much are you taking?

#117 Mr Matsubayashi

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Posted 03 September 2013 - 03:09 AM

First day on Up-ya-nose Cere

Applicator is a cheap disposable spray bottle from ebay. Some solution does try to exit my nose on the front side and later succeeds in going down the back of my throat. Tastes gross. I will need to look into this more diligently like many of you already have. I have not diluted or in any other way modified the solution.

The effects feel like the Cere i know. All in all, this is a win over injections. It will take a month before I'm convinced entirely. Provided the applicator doesn't make you look like a druggy this may be a way to keep the peak effects sustained all day. A second but less important win is how much cheaper this is.


How much are you taking?


Too much apparently. I used to do 10ml IM to good effect. I have done IN 3-4 times today, both sides and now I have brain fog.

Brain fog is a common side when too much Cere is taken.

I will need to determine best dosing through trial and error. Based on this I will know what ampule and IN bottle size to buy in future.

I have improved my IN technique and I can say the cheap disposable bottles work just fine for me.

Also a heads up to everyone, I'm pretty sure the Cere ampule glass blocks UV light. If you're storing Cere in a syringe its shelf life might be reduced in part due to UV exposure.

Edited by Mr Matsubayashi, 03 September 2013 - 03:27 AM.


#118 Krabby

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Posted 03 September 2013 - 06:34 PM

I’m pretty disappointed, I have not really got any effect from Cerebrolysin at all and it has been 5 days. I’m thinking of maybe upping the dose but I’m not sure that it is good for my nasal wall. I hope that I am applying it correctly.

On another note I have been off it for 2 days and I am suddenly feeling really spaced out and stupid.

#119 gerass

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Posted 03 September 2013 - 08:06 PM

Can someone tell me if you would need a needle to get the stuff out of the Vials? Or is it pourable? I love to try this stuff but just can't have needles about the place due to being an x drug user.

Was planing on using it in a nasal pump spray.


You can pour the cerebrolysin off the vial with some effort using the soaking hose of nasal spray which I done :) I also thought that it will pour when breaking off, but its not the case, cerebro is somewhat dense in order to get it from thin orifice. Also some basic pipette can be used to do the work.



Good info thanks.

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#120 sunshinefrost

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Posted 03 September 2013 - 09:25 PM

I’m pretty disappointed, I have not really got any effect from Cerebrolysin at all and it has been 5 days. I’m thinking of maybe upping the dose but I’m not sure that it is good for my nasal wall. I hope that I am applying it correctly.

On another note I have been off it for 2 days and I am suddenly feeling really spaced out and stupid.


It took me 11 days to start responding. Keep it up its worth it imo ;)





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