40 replies to this topic

[hamishm00]

For its positive effects on Gerd as well as its anti cancer and anti glycation properties?

[david ellis]

is this a good product to buy http://www.amazon.co...ords=d-limonene
says pure d-limonene cleansing agent but it mentions YOU CAN SAFELY DRINK IT dunno if it should be consumed very little or it gets bad.

Yes, that is a good product to buy. That bottle looks exactly like the bottle I bought from ebay. I used it for cleaning mostly, but I consumed some to kill the body odor of DMSO. That plastic bottle is pretty durable(PET), it will last well over a year before it starts to collapse. Putting it in a glass container from the beginning is a good idea if you aren't going to use it up.quickly.

d-limonene goes through cheaper plastic in a few months, caustic is an accurate description., It is strong stuff. I pour my doses on bread to buffer it. I wasn't looking for an anxiolytic effect so if there was one, I missed it.

why would you consume if you werent looking for the anxyolytic effect ?

"I consumed some to kill the body odor of DMSO. "

[socialpiranha]

Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor and panic disorder.

http://www.ncbi.nlm....pubmed/14666117

D-Limonene, a natural cyclic terpene, is an agonistic ligand for adenosine A(2A) receptors.

http://www.deepdyve....sine-zeyIKKCwbS



A caffeine challenge test in panic disorder patients, their healthy first-degree relatives, and healthy controls

http://www.ncbi.nlm....pubmed/17823963


Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens

http://www.ncbi.nlm....pubmed/21734299

[normalizing]

does anyone already use d-limonene with positive effect ? if not, amazon has cheap sources for sell. someone should give it a try, im just not capable at the moment

[Dakman]

I used it twice daily for approx 6mths. At first I did notice an improvement in relation to gerd issues I was having but nothing at all in terms of anxiety relief

[socialpiranha]

what was the dosage you used? i'm wondering if maybe the dosage needs to be quite a bit higher than for gerd

[Dakman]

I just filled two 0 sized caps twice daily, I don't think I came across any recommended dosage for anxiety while looking at information.

[normalizing]

doesnt seem too promising then but since it says its non-toxic i think you could have bumped the dose higher and tried that.

[Volcanic]

More on this, in relation to "stress" rather than "anxiety": http://online.lieber...9/rej.2013.1515

 

Stress is closely linked by its biological mechanisms to inflammation and by its consequences to accelerated aging. Stress triggers a hormonal response along the hypothalamus–pituitary–adrenal (HPA) axis, which can disrupt the ortho/parasympathetic balance essential for a harmonious life. Proper nutrition, adequate physical activity, and limiting the harmful influence of stress play important roles in avoiding the development of disease and promoting healthy aging. d-Limonene, a monoterpene shown to reduce inflammatory parameters in several pre-clinical and clinical models, could also produce an anti-stress action by altering ortho/parasympathetic parameters as well as central neurotransmitter functions. Here we report on a rat model, where a functional observational battery (FOB) was performed by submitting animals to non-pathological stress. d-Limonene or its metabolite perillyl alcohol (POH) were administered per os at a dose of 10 mg/kg. FOB tests were performed 1 hr before gavage and then at 60, 120, and 180 min. These tests confirmed the stressed status of control rats fed vehicle. Conversely, a series of parameters were significantly less disturbed in treated rats, who retained a better activity and displayed less signs of stress. These effects were more pronounced and sustained after ingestion of d-limonene than POH, suggesting the role of endogeneous metabolization of the terpene. These studies show that d-limonene exerts, through its metabolite POH, a significant anti-stress action measurable by behavioral and physiologic parameters under the influence of the nervous system. In addition to its anti-inflammatory effects, a beneficial role as an anti-stress substance could thus be claimed for d-limonene used as a dietary supplement.

 

[protoject]

Slightly off topic: by weight, how much d-limonene is in lemons and limes?

 

or do they only contain the L isomer?

 

Limonins are awesome..

[Blankspace]

Slightly off topic: by weight, how much d-limonene is in lemons and limes?

 

or do they only contain the L isomer?

 

Limonins are awesome..

 

Limonene content of the exterior rind (wt/wt) for lemons(2.97%), grapefruit(2.86%), and oranges(1.63%):

http://www.perkinelm...nds_By_GCMS.pdf

 

Citrus fruits contain mostly the "D" isomer (98%+)

Citronella + Lemongrass contain mostly the "L" isomer (96%+)

http://monographs.ia...56/mono56-9.pdf

Edited by Blankspace, 13 May 2014 - 04:09 PM.