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Galantamine and Smoking Cessation


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#1 REGIMEN

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Posted 07 June 2005 - 06:56 PM


***Could Galantamine possibly be used as part of cessation therapy for tobacco smoking?***

I don't understand the neurochemistry described in the 600+ Galantamine entries on PubMed and would like to hear from the more acquainted on this topic.

My thoughts on Galantamine being used for smoking cessation would be as a therapeutic treatment to not so much chemically stop the craving, but to replace the nicotinic stimulation of smoking with the nicotinic and cognitively enhancing effects of Galantamine use. Popping a dose when the craving hits as a replacement to ween someone off of smoking is what I think may be a possiblity if my understanding is on line with the actual workings of the drug.

The person I hope this information to help smokes a pipe and could also use the neuroprotective and anti-depressive actions of Galantamine.

#2 johnmk

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Posted 07 June 2005 - 07:55 PM

I cannot comment at this point on galantamine, but can definitely suggest oral deprenyl/selegiline liquid. In fact, at least one study has been performed that showed selegiline hydrochloride tablets (I'm not sure of the dose) resulted in a threefold improvement in smoking cessation (45% success vs. 15% success on placebo).

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#3 REGIMEN

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Posted 08 June 2005 - 12:01 AM

I may have come at the issue from the wrong end by narrowing in on one means before taking a survey of applicable options, but onyl for practical reasons as I have Galantamine on hand and from what I remember it is cheaper and easier to procure than Deprenyl.

Does anyone have any info on the Galantamine question?
If not I will probably move on to researching Deprenyl (thanks, johnmk).

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#4 LifeMirage

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Posted 08 June 2005 - 07:02 AM

***Could Galantamine possibly be used as part of cessation therapy for tobacco smoking?***

I don't understand the neurochemistry described in the 600+ Galantamine entries on PubMed and would like to hear from the more acquainted on this topic.

My thoughts on Galantamine being used for smoking cessation would be as a therapeutic treatment to not so much chemically stop the craving, but to replace the nicotinic stimulation of smoking with the nicotinic and cognitively enhancing effects of Galantamine use. Popping a dose when the craving hits as a replacement to ween someone off of smoking is what I think may be a possiblity if my understanding is on line with the actual workings of the drug.

The person I hope this information to help smokes a pipe and could also use the neuroprotective and anti-depressive actions of Galantamine.



Yes it can. I've given it to only a dozen or so people but it can help.




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