I am really a newbie on all this and I was just wondering if there is a connection between these two aging related therapies.
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Is there a connection between SIRT1 and telomerase?
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follies
, Nov 09 2013 04:22 PM
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#2
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Posted 10 November 2013 - 07:57 PM
It depends. This study says SIRT1 has a positive effect on telomerase expression in vivo in mice:
http://www.uccs.edu/...010_2118732.pdf
This older study found just the opposite. That SIRT1 deficiency stimulates telomerase expression. But that finding was in HeLa cervical cancer cells in vitro:
http://www.molbiolce...3/1210.full.pdf
Howard
http://www.uccs.edu/...010_2118732.pdf
This older study found just the opposite. That SIRT1 deficiency stimulates telomerase expression. But that finding was in HeLa cervical cancer cells in vitro:
http://www.molbiolce...3/1210.full.pdf
Howard
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