11 replies to this topic

[Reformed-Redan]

So, I got prescribed adderall IR. I took the Teva generic 20mg in half, that is 10mg for an initial dose. All I can say is wow. It was almost too good. I felt like 10mg was too much for me. After 6 hours I was still going and just felt tired of all the stimulation. I might try and see how 5mg works. I'd love to get away with as little as possible with this gem. Hell, if I can use selegiline and 2.5mg adderall, that would be almost perfect though I wonder how my social interactions would look like, eek!

So, I'm wondering if I should ask for something a little lighter, like focalin as I've tried ritalin IR and it's too short and gives me anxiety and slight paranoia. What do you guys think. Just want to milk this gem as long as possible for my ADD. Any suggestions? Thanks!

[Reformed-Redan]

BTW, I'm glad I didn't stick with the Gaspari Detonate stuff, it's way too strong on the NE area. Just makes you really spastic and anxious after a while. Not worth it, IMO.

[norepinephrine]

Agreed, Detonate is rather anxiogenic. I find such effects can be ameliorated with theanine and ashwagandha, but it still an inferior substitute to the real thing.

[Reformed-Redan]

Anyone know if focalin is comparable with adderall? With adderall being 10, where does focalin stand?

[3AlarmLampscooter]

Two totally different beasts. I've heard the stimulant potency is roughly equivalent from d-methylphenidate (Focalin) to 25/75 l-amphetamine/d-amphetamine (Adderall)

Effects are a lot different though, for one methylphenidate is very short acting by comparison. It also feels a lot more "tweaky" than adderall, and IMO a bit less motivating.

I'd recommend Dexedrine or Vyvanse out of all the currently approved ADHD meds, you'll notice they are a lot "smoother" than either Adderall or Focalin. Combining low doses of Selegiline and Adderall is overall a good strategy, even better with Dexedrine/Vyvanse. You'll notice it reduces the side effects a lot for the same stimulant potency if you can still function socially. You could also try Desoxyn, if your doctor is willing to prescribe it; it's around double the stimulant potency and shouldn't pose neurotoxicity issues at doses that low if you take a lot of antioxidants and selegiline.

Really though, I'm a bigger fan of 2-FMA than even Vyvanse. It's an RC, but second only to Armodafinil in "smoothness" for very impressive stimulant potency, and completely devoid of any crash/hangover.

[lourdaud]

IME focalin is much worse. Ritalin makes me weird and induces major tunnel vision, I presume it'd be even worse on focalin.

5 mg racemic amphetamine (the levo isomer is crucial) and/or 400 mg modafinil, preferably taken with artichoke extract and/or quercetin, works well for me.

Really though, I'm a bigger fan of 2-FMA than even Vyvanse. It's an RC, but second only to Armodafinil in "smoothness" for very impressive stimulant potency, and completely devoid of any crash/hangover.

Interesting! Is 2-FMA a DRI? How would you say it affects focus and cognition?

[3AlarmLampscooter]

IME focalin is much worse. Ritalin makes me weird and induces major tunnel vision, I presume it'd be even worse on focalin.

5 mg racemic amphetamine (the levo isomer is crucial) and/or 400 mg modafinil, preferably taken with artichoke extract and/or quercetin, works well for me.

Really though, I'm a bigger fan of 2-FMA than even Vyvanse. It's an RC, but second only to Armodafinil in "smoothness" for very impressive stimulant potency, and completely devoid of any crash/hangover.

Interesting! Is 2-FMA a DRI? How would you say it affects focus and cognition?

Funny, I really dislike the levo isomer of amphetamine. I find dexedrine so much more pleasant than adderall, let alone racemic amphetamine.

2-FMA hasn't yet been quantified for DRI/DRA+NRI/NRA+SRI/SRA activity, although from subjective effects I'd say it likely has fairly weak if any releasing agent and serotonergic properties. While it is only educated guessing, 2-FMA appears functions mostly as an SNDRI that is likely somewhat more dopamine heavy than regular amphetamine. I'd also hazard a more wild guess that the lack of crash from 2-FMA may come from far reduced VMAT2 antagonism compared to amphetamine, but I don't have any evidence to back this up.

2-FMA definitely helps my focus to a higher degree than d-amphetamine, and cognition perhaps a bit more. I wish someone would go to the trouble of coming up with in-vitro binding profiles for it like this study did with many other RCs. From all the anecdotal evidence I've read, it appears to be a great candidate for supplanting Vyvanse as the gold standard amphetamine.

[Metagene]

Hell, if I can use selegiline and 2.5mg adderall, that would be almost perfect though I wonder how my social interactions would look like, eek!

[Reformed-Redan]

Have you guys actually tried focalin. Thinking of giving it a try. Dexedrine and Vyvanse are somewhat cost prohibitive. Will try and give focalin a shot. If it works for 4 h at least with no major side effects, then I'm happy. Taking ritalin every hour was absurd for me plus it made me really anxious. That's how it worked. Spike then tapers off.

Hell, if I can use selegiline and 2.5mg adderall, that would be almost perfect though I wonder how my social interactions would look like, eek!

Hahaha! Lol.

[3AlarmLampscooter]

Admittedly, I've only tried instant release dexmethylphenidate. Reminded me of a smoother version of ethylphenidate (smoother than 80 grit sandpaper, right? ) more than Ritalin. Perhaps Focalin XR (if that's what you've got) is actually a smooth stim.

[brainslugged]

Vyvanse (basically d-amp) is great. If you can find insurance, my insurance covers vyvanse for almost the same price as the Generic racemic Amp ER. If focalin is covered, I would really look into vyvanse.

Also, concerta may be helpful since it is time-release. It was really nice for me, no redosing.

Finally, that initial feeling from amp does get dampened over time(for me at least). But the focusing effects stay full force, so don't get too discouraged.

2-FMA hasn't yet been quantified for DRI/DRA+NRI/NRA+SRI/SRA activity, although from subjective effects I'd say it likely has fairly weak if any releasing agent and serotonergic properties. While it is only educated guessing, 2-FMA appears functions mostly as an SNDRI that is likely somewhat more dopamine heavy than regular amphetamine. I'd also hazard a more wild guess that the lack of crash from 2-FMA may come from far reduced VMAT2 antagonism compared to amphetamine, but I don't have any evidence to back this up.

2-FMA definitely helps my focus to a higher degree than d-amphetamine, and cognition perhaps a bit more. I wish someone would go to the trouble of coming up with in-vitro binding profiles for it like this study did with many other RCs. From all the anecdotal evidence I've read, it appears to be a great candidate for supplanting Vyvanse as the gold standard amphetamine.

2-FMA is neat, but I don't know if it is worth risking due to the highly variable neurotoxicity and cardiotoxicity of phenylethylamines. Especially since learning that SRE properties are not necessarily tied to neurotoxicity, it is kinda worrying that it seems to happen with some randomness.

[Doc Psychoillogical]

MAKING THE SWITCH

 

From DEXEDRINE to FOCALIN

 

              What are your experiences Disliked or Approved with either medication?

                                Preferability of, Costs, Availabilities, Dosing, Forms:

*Generics *Brands *Manufacturer *Extended-release *Instant-release *Pro-drug  

 

                  How do they compare in effects negative & positive?

                                                                                               Effects if any, upon Individual:                                                    *Physicality*Mentality*Personablity(Interpersonal/self)*Emotionality*Sociability(Intrapersonal/others)

 

Differences/Similarities between the two? 

                                                                           What have you felt are the most:

                                                   *Pros *Cons *Benefits *Uses *Disadvantages *Advantages *Side effects...