There is a researcher/MD who believed ACE inhibitors and ANG blockers had anti aging and anti dementia type effects named David Moskowitz with GeoMed. The company is now defunct and I'm not sure that he even still practices medicine.
Several of his papers show that indeed ACE is overexpressed in aged animals compared to young animals and has a negative influence on catecholamine levels essential to neurotransmission.
The thing is that these drugs also have some side effects. The doses needed to realize benefit are therapeutic doses for high blood pressure which ultimately could cause worse effects for someone who does not need the medication.
It's probable
they are nootropic to some extent, though I believe taking something as common as piracetam probably would produce better nootropic results. A synergistic effect may exist but I'm not going to say I experienced one in the multiple years I tried ACE inhibitors and ANG antagonists. Possibly combining them with certain other nootropics may elicit better responses. It is nonetheless worth a trial to anyone especially who has high blood pressure.
You read in these patents of people patenting one hundred variations/chemicals for ten uses in one patent. To me it gets absurd at how many things they can claim in one patent for drug interactions. It is like putting 10,000 patents in one if you read some of them which use various drugs to treat multiple issues and actually successfully get the one patent claiming all of these combinations. It's hilarious to me because there is so much overlap amongst the different patents that if any of half of these jokers were to go to court, about one hundred other people with similar claims could go to court as well.
Edited by xks201, 17 December 2013 - 05:23 PM.