35 replies to this topic

[montana2012]

I really think that you are basing your entire explanation of what happened to you off the OP's post which is flawed in it's entirety.

 

 

I reached the "hypothalamus conclusion" independenly from him, I haven't been influenced by his research one bit. 

 

 

If anything, piracetam was beneficial in your case as it seems like you are a heavy drinker ('Plenty of beer').

 

 

 

I am the furthest thing from a heavy drinker you'll ever meet, aclohol depresses me. It just happened so that night, I was under alot of peer pressure.

 

 

Your statement about modafinil is incorrect, just because it is "active in the hypothalamus" does not mean that it is beneficial to the hypothalamus. What if it's action at various ligands in the hypothalamus induces oxadative stress? I'm not saying that it does, just illustrating that your justification for using modafinil does not make much sense.

 

 

 

The fact, that modafinil is helping me cannot be incorect, because I can feel the difference myself. I've never said, neither meant it's beneficial for the hypo, I just said it's active in there, I don't know exactly what it does there (except for boosting orexin).

 

I know my post is going to come off as a bit harsh, but I just want to reassure you that piracetam likely is not the culprit, so stop worrying!

 

 

 

I am not worried, I am desperate now. This thing is VERY real and it has neuroanatomical/neruochemical causes and it was caused by piracetam, PERIOD. 

 

 

Look, I know that my claims go against heavy research, but it's reality. Maybe I'm an unique case, maybe not. My twitching problems are certainly not unique and I haven't seen them mentioned in the literature ( correct me if I'm wrong). I've seen at least 5 cases online of people having long term brief muscle twitching from piracetam, have even talked to some people about it. I can link them if you want.

 

Best,

Steve

 

 

Edited by montana2012, 03 June 2014 - 08:10 PM.

[tazzz96]

I also have muscle twitching. Couple weeks ago it was for 2 days in my biceps. These past few days it's been the corner of my mouth. Nothing big, just annoying. It's been since i've been having piracetam. But the increase in brainpower has made up for it :-)

Sent from my Nexus 4 using Tapatalk

[FW900]

 

The fact, that modafinil is helping me cannot be incorect, because I can feel the difference myself. I've never said, neither meant it's beneficial for the hypo, I just said it's active in there, I don't know exactly what it does there (except for boosting orexin).

I know my post is going to come off as a bit harsh, but I just want to reassure you that piracetam likely is not the culprit, so stop worrying!

 

 

I am not worried, I am desperate now. This thing is VERY real and it has neuroanatomical/neruochemical causes and it was caused by piracetam, PERIOD. 

 

Look, I know that my claims go against heavy research, but it's reality. Maybe I'm an unique case, maybe not. My twitching problems are certainly not unique and I haven't seen them mentioned in the literature ( correct me if I'm wrong). I've seen at least 5 cases online of people having long term brief muscle twitching from piracetam, have even talked to some people about it. I can link them if you want.

 

I was saying that your theory, something being active in the hypothalamus and implying that it is good for it was incorrect; I was not disputing modafinil was helping you. I thought you were taking it because you read it affects the hypothalamus.

 

I've suffered from fasiculations (not racetam/supplement related)  the past several years of my life, what has helped me with them more than anything is eliminating stress from my life. B Vitamin complex and magnesium supplementation helps as well.

 

I believe piracetam may have induced your fasiculations (a very common side effect of many cholinergic drugs) but I still think you are worrying over something that is not as bad as you think it is. Please understand that your hypothalamus and brain are not damaged at all from your piracetam usage!

[Duchykins]

Probably something was imbalanced by supplementation. This is more common than most realize. It doesn't help that a lot of people want to deny such things because they don't want to think that they did it to themselves. Going by symptoms and circumstances, very likely electrolyte related, low potassium looks to be a culprit. With stopping the activities that were increasing electrolyte loss and continuing eating healthy the problem would have corrected itself in time... if it wasn't too acute.

Another possibility is acetylcholine, as wisely mentioned. Probably was more than one thing happening concurrently, this happened to me with Red Bull. Half a can sent me over the edge (after a salt and carb binge) and into hypokalemia and a trip on an ambulance. After solving the electrolyte imbalance with potassium, magnesium and taurine, certain symptoms continued. Turned out to be ACh elevated by a single nighttime dose of bacopa. A few symptoms persisted after stopping bacopa; turned out to be thiamine depletion caused by that first day with salt/carb binge, caffeine and hypokalemia. Problem solved by resuming daily multivitamin with extra 100mg thiamine, which I was never in the habit of taking regularly.

You really need to look over what you were doing that day and the previous few days. The answer is probably in there somewhere.

[montana2012]

Those fasciculations are not originating from mineral defficiency. I exercise alot and I know exactly how it feels to be Ca+/Mg+/K+ defficient. I have taken them in all forms (salts) and at various dosages. When I'm Ca+ deficient for example my heart would skip a beat every 4-5 beats, especially if I get up from my bed abruptly. Muscles cramp too (don't twitch). Take a pill and you're like new in 20 mins. Mg+ deficiency results in stress and tense muscles ( maybe a few twitches troughout the day). Potassium improves nerve conductance too and I helps with cramps I guess. However, post piracetam brief fasciculations are in a category of their own. First thing I did when I started getting them was to take a combined K+/Mg+ supplement and it did help me with my mood, but that was it. 

 

I shoot B1,B6,B12 up my butt for superior absorption. I take B9 and B3 on the side, too.

 

   They is absolutely without a doubt caused by piracetam. The ultimate proof is that they seize when I take a 800mg piracetam dose, then reappear after it weans off. Along with taking it I would experience a tremendous "mindfuck" even from such a small dose. It would take several months for the condition to better itself if I don't take Modafinil/Cerebrolysin. Interestingly, I experimented with aclohol in controlled condition to see if it can help me, and amazingly - it does. It has to be alot though and I don't like alcohol. Alcohol is the only thing that clears it 100%. Talk about weird brain chemistry...

 

Anyhow, I'm used to the twitching, it doesn't bother me, it's like breathing. The fact, that I cannot think straight is what sucks.

 

Stay safe,

Steve

Edited by montana2012, 04 June 2014 - 02:15 AM.

[montana2012]

also have muscle twitching. Couple weeks ago it was for 2 days in my biceps.

 

 

I am not talking about an occasional twitch episode, but rather permanent condition.

 

 

Those fasciculations are not originating from mineral defficiency. I exercise alot and I know exactly how it feels to be Ca+/Mg+/K+ defficient. I have taken them in all forms (salts) and at various dosages. When I'm Ca+ deficient for example my heart would skip a beat every 4-5 beats, especially if I get up from my bed abruptly. Muscles cramp too (don't twitch). Take a pill and you're like new in 20 mins. Mg+ deficiency results in stress and tense muscles ( maybe a few twitches troughout the day). Potassium improves nerve conductance too and I helps with cramps I guess. However, post piracetam brief fasciculations are in a category of their own. First thing I did when I started getting them was to take a combined K+/Mg+ supplement and it did help me with my mood, but that was it. 

 

I shoot B1,B6,B12 up my butt for superior absorption. I take B9 and B3 on the side, too.

 

   They is absolutely without a doubt caused by piracetam. The ultimate proof is that they seize when I take a 800mg piracetam dose, then reappear after it weans off. Along with taking it I would experience a tremendous "mindfuck" even from such a small dose. It would take several months for the condition to better itself if I don't take Modafinil/Cerebrolysin. Interestingly, I experimented with aclohol in controlled condition to see if it can help me, and amazingly - it does. It has to be alot though and I don't like alcohol. Alcohol is the only thing that clears it 100%. Talk about weird brain chemistry...

 

Anyhow, I'm used to the twitching, it doesn't bother me, it's like breathing. The fact, that I cannot think straight is what sucks.

 

Stay safe,

Steve

Edited by montana2012, 04 June 2014 - 02:18 AM.