9 replies to this topic

[Flex]

Hello there,

I wanted to ask if somebody knows anything about the current state of Crebinostat ?

Like:

Does it stay as a research chemical or will it be released ?

What is the safety profile ?
e,g, Carciogenic or does it cause irreversible changes to Cell metabolism, etc..

Feel free to discuss any related things to it.

Edited by Flex, 23 February 2014 - 01:41 AM.

[socialpiranha]

i have it on my current list of interesting substances

[Flex]

Glad to hear.

Edited by Flex, 26 February 2014 - 06:58 PM.

[socialpiranha]

crebinostat
evp-6124
gts-21
AHN 2-005
pitolisant
nsi-189
Ro4938581
i5ai
indeloxazine
c16
SB-258,585
enasculin
Ispronicline

[Flex]

Thx

[LexLux]

any updates?

[Flex]

Unfortunaetly not. I´m a bit worried, because there were no human trials made for this particular compound.

[LexLux]

that's a shame, there a post in this thread listing some HDACis that have gone into clinical trials: http://www.longecity...-aging-protein/

[BieraK]

Well, here is the full paper so we can take a deeper look into this
I've seen too much interest in HDAC inhibitors, specially HDAC2i for memory and plasticity.

Attached Files

•  Crebinostat A novel cognitive enhancer that inhibits histone deacetylase activity.pdf   1.82MB   7 downloads

[HappyShoe]

Last I saw I think they were selling it at THT.co