Exercise outperforms pretty much any known supplements and drugs by orders of magnitude as far as healthy biomarkers are concerned, so it should be at the top of the list before any supplements are even considered. Exercise should include weight training and some form of cardiovascular exercise (though perhaps not steady-state cardio).
I agree that exercise ( and a healthy diet ) are important aspects of any anti aging regimen.
It won't however necessarily effect many of the " biomarkers " that plague an aging body in a significant way.
It may support better hormone levels, but won't raise age related declining ones significantly ( DHEA, testosterone, melatonin etc )
It won't lower inflammation ( CRP, sedimentation rate ) age related or otherwise.
It won't improve methylation ( homocysteine )
It will support lower fasting blood glucose levels, but not inhibit glycation ( HbA1C )
It will support better lipid patterns, but not significantly adjust higher LDL 's in a person of normal weight.
It won't lower levels of oxidation, in fact it is pro oxidant.
It won't improve mineral/ nutrient status and make up for dietary deficiencies.
It supports a heathy lifespan, but won't potentiate a longer lifespan in a significant way as substances discussed like C60oo, MitoQ, nicotinamide riboside + resveratrol , PQQ, and others may...
That being said, I will reiterate that resistance / weight training and CV exercise, 45 minutes 4-5 days a week are a critical part of an overall longevity program.
An intelligent, targeted supplement ( drug ) regimen is complementary to an exercise and diet program, not a replacement for one.