7 replies to this topic

[Ichigo]

Hello,

 

From what I understand Picamilon is gaba + niacin, the niacin helps the gaba reach the brain..

 

My question is if anyone know how much niacin does picamilon in total actually contain? niacin itself have anti-anxiety properties, and you can take a dosage of at least 2 gram a day of niacin, so how does the dosage of niacin works out in picamilon?

 

Also, if I were to take nicotinamide (not niacin) with picamilon, would that increase the picamilon effect even more?

 

 

[mrnootropic]

Picamilon is synthesized from Gaba & Niacin which means Picamilon is its own unique chemical :4-(Pyridine-3-carbonylamino)butanoic acid.

 

Niacinamide works in a different way to Niacin. as does Picamilon.

Picamilon is its own chemical / substance, so when you take Picamilon as a pill, your not taking niacin even though it was created by combining Niacin & Gaba.

 

Picamilon has its own dosage, which can be found on longecity.

 

The dose of Picamilon is usually 20mg or 50mg -150mg. Some take more.

[deeptrance]

Picamilon is its own chemical / substance, so when you take Picamilon as a pill, your not taking niacin even though it was created by combining Niacin & Gaba.

What are the metabolites of picamilon? I would think they'd be niacin + GABA at first stage of metabolism, is this not correct?

[mrnootropic]

 

Picamilon is its own chemical / substance, so when you take Picamilon as a pill, your not taking niacin even though it was created by combining Niacin & Gaba.

What are the metabolites of picamilon? I would think they'd be niacin + GABA at first stage of metabolism, is this not correct?

 

yeah,

 

Did you read the OP's question ?

He is trying to determine how much Niacin is in his Picamilon supplement. 

 

I was trying to tell him that Picamilon is basically its own Substance and it will act different to both Gaba & Niacin.

 

I think the OP (Ichigo), thought that Picamilon is a blend of Niacin & Gaba, not an actual synthetic chemical made from Niacin & Gaba bonded.

 

By the way he was asking the question, it seemed as if he thought he was taking niacin and gaba blended. Because he asked how does the dosage of niacin work out in picamilon?

 

I dont think you can determine how much Niacin is in your picamilon supplement is what i was trying to say.

[deeptrance]

Did you read the OP's question ?
He is trying to determine how much Niacin is in his Picamilon supplement. 

Right, and it's a valid question if picamilon metabolizes to GABA + niacin. It's my understanding that picamilon is GABA bonded to niacin, and this allows for the GABA to be delivered across the blood-brain barrier. So if the objective is to get GABA to the brain efficiently, and the delivery method is to bond it with niacin, then it stands to reason that if GABA is a metabolite of picamilon then another metabolite should be niacin because, after all, that's what was bonded to the GABA before it entered the brain. But maybe there's some other reaction that takes place, such that you get GABA + something like niacin that isn't exactly niacin.

I've had the same question as the OP about picamilon, wondering if picamilon serves as a means of obtaining niacin, not because I thought it was a mixture of GABA and niacin but because niacin is a potential [likely?] metabolite.

Edited by deeptrance, 16 May 2014 - 11:37 PM.

[Duchykins]

I thought picamilon broke down into both GABA and nicotinic acid, and then they go about their business as usual

[Ichigo]

Thanks a lot for the answers guys!

 

I have been using picamilon for about 3 weeks (5 times a week with 2 days cycle) dosages 50-100, it really helps my social anxiety! and helps me to feel relax and calm in a very effective way! I used to take l-theanine before, but I had to take at least 400-700 MG of that for my physical symptoms not to show up, and it's not as effective as picamilon, picamilon is on another level!!!!

 

aside of that I always wanted to give Phenibut a try (yeah I know it's not a drug to use everyday) but.. let's say, would it be ok to use picamilon 3 days a week and phenibut 2 days a week.. will the effects of phenibut build up tolerance to picamilon as well? meaning, let's say I build tolerance to PHENIBUT, will that mean that when I use picamilon the next day I will have some degree of tolerance to picamilon as well because of phenibut?

 

PS: some sites/people state that picamlon is odorless and some say it has a chemical and sweet taste to it.. in my case the later is correct.. how come some say it's odorless and tasteless?? is there a difference between the powders?

Edited by Ichigo, 17 May 2014 - 11:33 AM.

[Juan Manuel Garrido]

There seems to be some evidence that cycling picamilon may be a good idea. The reason for this is that you may develop a tolerance to it over time. Also, the longer it is taken, the more severe the withdrawal symptoms can be once its use is stopped. 

Since cognitive benefits occur with long term use, some personal experimentation would be needed to determine the ideal cycle length of “on time” and “off time” to get the most out of supplementing with picamilon.

One manufacturer (Serious Nutrition Solutions) that sells picamilon recommends taking it in a five-day on and two-day off pattern, and taking two weeks off after four weeks of usage.