This little chemical has recently been getting on my mind quite a bit... it almost seems like a dream come true, even! A stimulant which doesn't give the usual side-effects - since it has such a highly selective mode of effect - it only agonises ONE receptor - and it so happens to be, precisely the most common faulty receptor in the ADHD -brain!
No heart-palpitations, no suicidal tendencies, no sweating, no itching, no nothing! One bullet - one kill.
http://en.wikipedia.org/wiki/A-412,997
A-412,997 is a drug which acts as a dopamine agonist that is used in scientific research. It is the first drug developed that is a highly selective agonist for the D4 subtype, with significantly improved selectivity over older D4-preferring compounds such as PD-168,077 and CP-226,269.[1] In animal tests it improved cognitive performance in rats to a similar extent as methylphenidate, but without producing place preference or other signs of abuse liability.[2][3] Also unlike other dopamine agonists, selective D4 agonists do not cause side effects such as sedation and nausea, and so might have advantages over older dopamine agonist drugs.[4]
SO! Anybody here who has more info on this? Such as if it's going through any trials as a new ADHD -med? I mean, the application seems obvious.
Perhaps there's even someone here who has experience with this drug? That would be outstanding, I must say!