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Vinpocetine vs. Hydergine


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15 replies to this topic

#1 virago

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Posted 21 August 2005 - 10:32 PM


As school is starting again shortly, I am trying to decide the best stack to help me combat my ADD, as well as aid in anti-aging, cognitive enhancement, etc. I am trying to decide between Hydergine and Vinpocetine. I have heard that Hydergine is stronger and more effective overall, but I have never heard it mentioned in any ADD-specific discussions. Any advice, or information on the differences between the two, especially in regards to combatting ADD?

#2 wannafulfill

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Posted 21 August 2005 - 11:21 PM

Neither of those nootropics have been use clinically to treat ADD, though they might help any healthy person with cognitive functioning. Pyritinol has, and would probably benefit you at 500mg IMO.

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#3 worldeater

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Posted 21 August 2005 - 11:28 PM

Neither of those nootropics have been use clinically to treat ADD, though they might help any healthy person with cognitive functioning. Pyritinol has, and would probably benefit you at 500mg IMO.


Were you taking 500mg Pyritinol all at once, or divided into two 250mg doses?

#4 wannafulfill

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Posted 22 August 2005 - 12:13 AM

at once in the morning, with food

#5 zoolander

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Posted 22 August 2005 - 10:48 AM

I read alot of threads here about people with ADD. I am not aware of the incident of ADD in todays society but it seems to me that alot of people think that they have it.

Have you clinically been diagnosed with ADD?

#6 losty

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Posted 22 August 2005 - 09:59 PM

Yeah there alot of people afflicted not with clinical ADD but something alot more sinister......super
attentional desires. Really its just SAD! lol Im a sufferer.

ADD is a pretty loose term really. "Attention deficit disorder" So any disorder that causes a deficit in attention. A disordered mind from lazy habits?? Maybe they are just plain not interested in somethings ? A gorgeous member of the opposite sex or threats of violence tend to grab the "uninterested" ADD "sufferers" attention.

ADD has become a cliche used to describe anything other than optimum performance.Thats OK, there is nothing wrong with being unsatisfied with mediocrity.

Should ADD be only used to describe attentional deficits of a certain origin? Such as actual neurological disorders.

#7 johnmk

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Posted 22 August 2005 - 11:41 PM

The term "ADHD" is applied with such generosity these days, it really should be thought of more as a continuum, i.e. we all have it, as we all have intelligence, memory, and skin pigment. It should perhaps more correctly be thought of as frontal cortex sub-optimal function. Of course, what's sub-optimal to one may not be to another. I take dextro-amphetamine at a low dose and it seems to give me everything that I need. I have even grown a "reverse" tolerance to the medication, which theory and anecdote support as being possible as well. I need less and less to achieve the desired effect. Nobody here would recommend dextro-amphetamine however because there are some studies showing it as neurotoxic. The flipside is that the human brain will atrophy like any muscle if not used and flexed, so to speak. The medication helps me use my full brain in a more efficient manner, allows me to think more intelligently, coherently, and make the kinds of connections that I normally wouldn't make. Almost needless to say I am also far less distractable, hyperactive, and more patient with activities and people I wouldn't normally be patient with.

#8 mitkat

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Posted 22 August 2005 - 11:41 PM

ADD has become one of those generic socially constructed problems that too many people think they have.

Like wannafulfill said, I think pyritinol is a good start. I've been enjoying it's focusing effects as well.

#9 johnmk

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Posted 23 August 2005 - 12:17 AM

ADHD is in my opinion as much genetic as it is environmental. Inasmuch as ADHD exists in a given individual in the year 1900, let's say, it's tremendously amplified in this day and age where the learning experience of patience, slowing down, etc., exists less so than it should. Whereas 3% of those in centuries prior might have fit the DSM-IV criteria, it is multiples of that today.

#10 mitkat

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Posted 23 August 2005 - 12:19 AM

johnmk, would you agree with that idea that watching sesame street has totally jived an entire generation with ADHD?

#11 johnmk

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Posted 23 August 2005 - 12:40 AM

Perhaps. Sesame Street is better than a few alternative TV series however -- while being educational.

#12 mitkat

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Posted 23 August 2005 - 12:45 AM

That's true. I always think of my generation (23 years old) and our shows. But now...with the advent of the Teletubbies, etc, who knows what the hyper-stimulated future will hold?

now i'm officially off-topic.

#13 power.bulls.x

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Posted 23 August 2005 - 05:16 PM

DMAE is quite toxic in large amount but have shown grete results for ADD

#14 dopamine

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Posted 24 August 2005 - 12:18 AM

For ADD I would say the best drug (besides the obvious amphetamines) would be Deprenyl with DL-Phenylalanine. It's been shown to be similar to Ritalin (methylphenidate) in treating ADD symptoms.

J Child Adolesc Psychopharmacol. 2004 Fall;14(3):418-25.

Selegiline in comparison with methylphenidate in attention deficit hyperactivity disorder children and adolescents in a double-blind, randomized clinical trial.

Department of Psychiatry, Tehran University of Medical Sciences, Psychiatry and Clinical Psychology Research Center, Roozbeh Hospital, Tehran, Iran.

OBJECTIVES: The aim of this study was to examine the selegiline treatment compared to methylphenidate (MPH) in children and adolescents with attention deficit hyperactivity disorder (ADHD). METHOD: Forty subjects, aged 6-15 years, boys and girls, who were diagnosed as having ADHD, using the criteria of the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV), were randomly assigned to receive either selegiline or MPH for 60 days. Treatment outcomes were assessed using the Attention Deficit Hyperactivity Scale (ADHS) administered at baseline and on days 14, 28, 42, and 60 following the commencement of treatment. Side effects were also rated. RESULTS: There were no significant differences between sex, age, weight, and ethnicity of participants in the 2 groups. Both groups showed a significant improvement over the 60 days of treatment resulting from the teachers' and parents' ADHS scores across the treatment. CONCLUSION: Following the trial, MPH did not effect greater mean improvement as a result of the parents' or teachers' ADHS scores than selegiline. Thus, selegiline appears to be effective and well tolerated for ADHD in children and adolescents.


Strattera is good if you have medical insurance to cover most of the bill, otherwise it is prohibitively expensive.

#15 liorrh

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Posted 24 August 2005 - 12:43 AM

wouldnt your purposal cause habituation dopamine?
I fealt habitauted to DLPA by itself :-(

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#16 dopamine

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Posted 24 August 2005 - 09:01 PM

I think that Deprenyl + DLPA would result in much less habituation than any of the amphetamines used in treating ADD, in particular Dexedrine (pure d-amphetamine).




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