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Staphylococcus aureus colonization and skin, sinus, and major chronic disease

allergies chronic disease nasal skin disease staphylococcus aureus colonization ear infection staph sinusitis

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#1 Healthy Almonds

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Posted 17 November 2015 - 12:50 AM


Staphylococcus aureus colonization in the nostrils or ears may be responsible for or associated with many skin, sinus, and major chronic diseases.

 

The role of nasal carriage in Staphylococcus aureus infections

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Skin diseases

 

Acne/folliculitis

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Prevalence of S. aureus in chronic ear infections

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High Prevalence of Superantigens Associated with Staphylococcus aureus Isolates from Patients with Atopic Eczema

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Erythromycin-resistant S. aureus strains commonly isolated from impetigo.

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High prevalence of nasal Staphylococcus aureus in patients with psoriasis

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Rosacea and S. aureus presence

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Sinus conditions

 

Correlation between nasal carriage rate of Staphylococcus aureus and the development of symptoms of persistent allergies

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A significant association between Staphylococcus aureus colonization and asthma

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Reduction of  post nasal drip intensity after mucotomy depended on Staphylococcus aureus colonization of the nose

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A review of recent literature shows a high incidence of positive cultures for  Staphylococcus aureus from the sinuses of patients with sinusitis

→ source (external link)

 

 

 

 

 

Chronic disease

 

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide


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Staphylococcus vaccine effectively reduces symptoms of chronic fatigue syndrome/fibromyalgia

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Epidermolysis bullosa patients suffering from chronic wounds were 100% colonized by Staphylococcus aureus

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Obesity is a possible determinant for S. aureus nasal colonization

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Staphylococcus aureus carriage is common in patients with rheumatoid arthritis

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Relapse of  systemic lupus erythematosus in patients having S. aureus in their nasal mucosa is higher than in patients without.

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Chronic exposure to a toxin made by Staphylococcus aureus (staph) bacteria produces the hallmark symptoms of Type 2 diabetes

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Chronic sinusitis may be associated with the following diseases

 

Risk of  myocardial infarction in patients with rhinosinusitis.


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Myopia is due to a localization of organisms or their toxins from a foreign focus. Evidence is offered that paranasal sinusitis may be a prominent cause

→ source (external link)

 

The incidence of sinus disease in  multiple sclerosis patients is higher than in some other studies of normal populations.

→ source (external link)

 

Rhinorrhea is increased in  Parkinson's disease.


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Link Between Sinus Problems and  Sleep Apnea

→ source (external link)

 

 

The Surprising Connection Between Your Sinuses and  Stroke


→ source (external link)

 


Edited by Healthy Almonds, 17 November 2015 - 01:32 AM.

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#2 panhedonic

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Posted 22 November 2015 - 08:38 AM

I'm pretty sure I have them in my nostril . How can I get rid of them?

#3 chemicalambrosia

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Posted 22 November 2015 - 01:01 PM

I've ran into an interesting website/blog that has a working theory that sinus problems are more likely due to lack of beneficial bacteria(specifically lactobacillus sakei) and less due to presence of bad bacteria. There are a number of studies that somewhat support this. These people are putting kimchi juice into their nostrils to colonize their sinuses with lactobacillus sakei and getting very good results(eradication of chronic sinusitis). 

 

Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis.

http://www.ncbi.nlm....pubmed/22972842

 

http://lactobacto.co...bacillus-sakei/

 

Probiotics and sinusitis treatment go hand in hand. In the last few years research found that the one probiotic (beneficial bacteria) that chronic sinusitis sufferers lack and that treats and cures sinusitis is Lactobacillus sakei. The researchers Abreu et al found in their 2012 study that not only do sinusitis sufferers lack L. sakei, they have too much of Corynebacterium tuberculostearicum (normally a harmless skin bacteria), and they also don't have the bacteria diversity in their sinuses that healthy people without sinusitis have. Of course those researchers are working on beneficial bacteria nasal sprays, but that will take a while.

 

http://lactobacto.co...onic-sinusitis/

 

 

Last year a small study by Abreu et al raised the exciting possibility that the sinus microbiome (the microbial community in our sinuses) being seriously out of whack could be behind chronic sinusitis. Which some day could result in sinusitis treatment being the restoration of beneficial microorganisms that should be there, perhaps with a nasal spray. From Science Daily, September 12, 2012:

Sinusitis Linked to Microbial Diversity

A common bacteria ever-present on the human skin and previously considered harmless, may, in fact, be the culprit behind chronic sinusitis, a painful, recurring swelling of the sinuses that strikes more than one in ten Americans each year, according to a study by scientists at the University of California, San Francisco.

The team reports this week in the journal Science Translational Medicine that sinusitis may be linked to the loss of normal microbial diversity within the sinuses following an infection and the subsequent colonization of the sinuses by the culprit bacterium, which is called Corynebacterium tuberculostearicum.

In their study, the researchers compared the microbial communities in samples from the sinuses of 10 patients with sinusitis and from 10 healthy people, and showed that the sinusitis patients lacked a slew of bacteria that were present in the healthy individuals. The patients also had large increases in the amount of Corynebacterium tuberculostearicum in their sinuses, which are located in the forehead, cheeks and eyes.

The team also identified a common bacterium found within the sinuses of healthy people called Lactobacillus sakei that seems to help the body naturally ward off sinusitis. In laboratory experiments, inoculating mice with this one bacterium defended them against the condition. 

"Presumably these are sinus-protective species," said Susan Lynch, PhD, an associate professor of medicine and director of the Colitis and Crohn's Disease Microbiome Research Core at UCSF. What it all suggests, she added, is that the sinuses are home to a diverse "microbiome" that includes protective bacteria. These "microbial shields" are lost during chronic sinusitis, she said, and restoring the natural microbial ecology may be a way of mitigating this common condition.

Though the sinuses' underlying purpose is still unclear, they are all too familiar to American doctors and their patients because of what happens when the thin tissues lining them become inflamed, as occurs in chronic sinusitis -- one of the most common reasons why people go to the doctor in the United States. There are about 30 million cases each year, and the cost to the healthcare system is an estimated $2.4 billion dollars annually.

The pain of sinusitis can last for months. Doctors typically prescribe bacteria-killing antibiotics and, in more severe and long-lasting cases, conduct sinus surgeries. However, said Andrew Goldberg, MSCE, MD, the director of rhinology and sinus surgery at UCSF and a co-author on the paper, "the premise for our understanding of chronic sinusitis and therapeutic treatment appears to be wrong, and a different therapeutic strategy seems appropriate."

 

http://lactobacto.co...-and-sinusitis/

http://lactobacto.com/our-story/

http://lactobacto.co...atment-summary/

 



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#4 Healthy Almonds

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Posted 22 November 2015 - 09:58 PM

I'm pretty sure I have them in my nostril . How can I get rid of them?

 

Your doctor can help you definitively determine whether you carry Staph in your nostrils. If positive, the doctor may prescribe the topical antibiotic Mupirocin http://www.mayoclini...on/drg-20064917 or other intra-nasal antibiotics.

 

If you live in the US you can run to a drugstore and pick up Triple Antibiotic Ointment (Neosporin) http://www.ncbi.nlm....pubmed/23377521. Neosporin helped get rid of my nasal Staph. 


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#5 Healthy Almonds

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Posted 22 November 2015 - 10:18 PM

I've ran into an interesting website/blog that has a working theory that sinus problems are more likely due to lack of beneficial bacteria(specifically lactobacillus sakei) and less due to presence of bad bacteria. There are a number of studies that somewhat support this. These people are putting kimchi juice into their nostrils to colonize their sinuses with lactobacillus sakei and getting very good results(eradication of chronic sinusitis). 

 

Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis.

http://www.ncbi.nlm....pubmed/22972842

 

http://lactobacto.co...bacillus-sakei/

 

 

 

Ah, that's an interesting idea. I can definitely see how microbial competition in the nasal passages discourages or encourages the growth of some bacteria.  Here's one about Staphylococcus epidermidis preventing S. aureus attachment to the nasal passages http://www.ncbi.nlm....pubmed/23316041. Here's another one about S. epidermidis and Corynebacterium preventing Staph growth  http://www.ncbi.nlm....cles/PMC152380/.



#6 panhedonic

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Posted 23 November 2015 - 08:05 AM

Almonds, tried both to no avail. How long should I stick with each? I did a couple of weeks of each at different points.

#7 Healthy Almonds

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Posted 23 November 2015 - 08:19 PM

Almonds, tried both to no avail. How long should I stick with each? I did a couple of weeks of each at different points.

 

Staph can attach to the hair follicles of the nose http://www.ncbi.nlm....pubmed/20864209. You may see benefit from trimming your nose hairs.

 

Also, you can try wiping your ears with rubbing alcohol http://www.webmd.com...-ear-prevention. I can speak for its ability to significantly reduce the amount of ear Staph that I had.

 

I also dunk a cotton swab in the alcohol and rub it around the front of my nostrils. I believe that has helped as well. If you try the nose method, be sure to focus only on the front of your nostrils, as it may feel uncomfortable if the alcohol gets too far back.



#8 vader

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Posted 18 February 2017 - 12:37 PM

95 million Americans carry S aureus in the nose. Seems like the research is flawed (might as well tell that sinusitis is caused by having a nose).







Also tagged with one or more of these keywords: allergies, chronic disease, nasal, skin disease, staphylococcus aureus colonization, ear infection, staph, sinusitis

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