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[mfoundation] ‘Groundbreaking’ Stem Cell Treatment Could Regrow Limbs, Repair Bones

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#1 ImmInst

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Posted 07 April 2016 - 07:46 PM

image: http://www.redorbit....16/04/cells.jpg

Human cells isolated

APRIL 5, 2016

‘Groundbreaking’ stem cell treatment could regrow limbs, repair bones

In the pages of comic books and on the silver screen, superheroes like Wolverine and Deadpool have a “healing factor” that allows their bodies to regenerate and recover from injuries or illness at an amazing rate – but certainly nothing like that is possible in real life, right?

Amazingly, a team of scientists led by John Pimanda, a hematologist and associate professor at the University of New South Wales in Australia, published a study in Monday’s edition of the journal PNAS reporting that they had successfully reprogrammed bone and fat cells into induced multipotent stem cells (iMS) – the first step to making such a repair system a reality.

As they explained in a statement, stem cell therapies using iMS cells could theoretically repair a fractured bone or fix injured spinal discs, using a technique similar to how salamanders are able to regenerate lost limbs. These treatments could radically alter the field of regenerative medicine, and perhaps most surprisingly, the authors believe they could be available in just a few years.  The technique, which has been successfully tested in mice, “is a significant advance on many of the current unproven stem cell therapies, which have shown little or no objective evidence they contribute directly to new tissue formation,” Pimanda said.

Human trials could begin by the end of 2017

Read more at http://www.redorbit....IPDBBg2QCgD3.99

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#2 Michael Farrington

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Posted 21 April 2016 - 12:31 AM

End of 2017. Not too far away!

#3 ceridwen

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Posted 21 April 2016 - 01:14 PM

For human trials

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#4 Antonio2014

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Posted 22 April 2016 - 01:46 PM

Why is this so groundbreaking?? :|?  Multipotent stem cells have less potency than pluripotent stem cells, and induced pluripotent stem cells exist since some years ago.

Potency specifies the differentiation potential (the potential to differentiate into different cell types) of the stem cell.[4]

  • Totipotent (a.k.a. omnipotent) stem cells can differentiate into embryonic and extraembryonic cell types. Such cells can construct a complete, viable organism.[4] These cells are produced from the fusion of an egg and sperm cell. Cells produced by the first few divisions of the fertilized egg are also totipotent.[5]
  • Pluripotent stem cells are the descendants of totipotent cells and can differentiate into nearly all cells,[4] i.e. cells derived from any of the three germ layers.[6]
  • Multipotent stem cells can differentiate into a number of cell types, but only those of a closely related family of cells.[4]
  • Oligopotent stem cells can differentiate into only a few cell types, such as lymphoid or myeloid stem cells.[4]
  • Unipotent cells can produce only one cell type, their own,[4] but have the property of self-renewal, which distinguishes them from non-stem cells (e.g. progenitor cells, muscle stem cells).




Edited by Antonio2014, 22 April 2016 - 01:48 PM.

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#5 Nate-2004

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Posted 14 May 2016 - 03:37 PM

I see news like this a lot over the years. Then it goes away never to be heard from again. 


Like this: http://news.rice.edu...ows-when-to-go/  I mean, wtf happened to that? You never find out. So many other technologies just gone, like artificial trees that soak up way more CO2, etc.. Where did those go?


We'll see if Human trials actually begin in 2017, though I'd love to know what the year and a half hold up is. I'm guessing the FDA, that slow moving, ultra-bureaucratic mega monopoly is always in the way of everything and anything that could be seen as life saving progress or relief of suffering.

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