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              Advocacy & Research for Unlimited Lifespans

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Brown/Beige Adipose Tissue Activation (BAT) via Cold Exposure and Diet for Health and Longevity

bat cold exposure longevity blood glucose

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#31 Gordo

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Posted 24 May 2017 - 05:44 PM



Why can't there be BAT under head's skin tissue, like in others bodys skin areas? I would understand there will be less proportionally than in other areas, but not at all?


Substantial quantities of brown adipose tissue can be detected in adult humans using positron-emission tomography, especially when the individuals are exposed to cold temperatures. Most of this tissue in adults is located in the lower neck and supraclavicular region.

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Here are some pictures.


BAT anchors to bone like muscle does, but the skull/head is mostly skin and bone on the outside, not much fat. 



Edited by Gordo, 24 May 2017 - 05:46 PM.

#32 Brian

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Posted 24 May 2017 - 06:46 PM

True, however keep in mind besides BAT there is also "beige fat" found closer to the surface of the skin. And on top of that there are changes that occur in muscles after CE that allow them to generate heat without shivering (sarcolipin is one example).

#33 Gordo

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Posted 25 June 2017 - 12:03 PM

Siems WG, van Kuijk FJ, Maass R, Brenke R.
Ten healthy subjects who swim regularly in ice-cold water during the winter (winter swimming), were evaluated before and after this short-term whole body exposure. A drastic decrease in plasma uric acid concentration was observed during and following the exposure to the cold stimulus. We hypothesize that the uric acid decrease can be caused by its consumption after formation of oxygen radicals. In addition, the erythrocytic level of oxidized glutathione and the ratio of oxidized glutathione/total glutathione also increased following cold exposure, which supports this hypothesis. Furthermore, the baseline concentration of reduced glutathione was increased and the concentration of oxidized glutathione was decreased in the erythrocytes of winter swimmers as compared to those of non-winter swimmers. This can be viewed as an adaptation to repeated oxidative stress, and is postulated as mechanism for body hardening. Hardening is the exposure to a natural, e.g., thermal stimulus, resulting in an increased tolerance to stress, e.g., diseases. Exposure to repeated intensive short-term cold stimuli is often applied in hydrotherapy, which is used in physical medicine for hardening.
It looks like cold exposure acts as an exercise for the defense system against oxidative stress. You lose some of your endogenous antioxidants, but improve your overall capacity in the long run. 

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